| Full name: adenylate kinase 9 | Alias Symbol: FLJ42177|FLJ25791|dJ70A9.1|MGC26954 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 221264 | HGNC ID: HGNC:33814 | Ensembl Gene: ENSG00000155085 | OMIM ID: 615358 |
| Drug and gene relationship at DGIdb | |||
Expression of AK9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AK9 | 221264 | 1564002_a_at | -0.8579 | 0.0152 | |
| GSE26886 | AK9 | 221264 | 1552299_at | -1.1454 | 0.0000 | |
| GSE45670 | AK9 | 221264 | 1564002_a_at | -0.7013 | 0.0004 | |
| GSE53622 | AK9 | 221264 | 98983 | -1.0341 | 0.0000 | |
| GSE53624 | AK9 | 221264 | 98983 | -1.1613 | 0.0000 | |
| GSE63941 | AK9 | 221264 | 1564002_a_at | 1.3067 | 0.0618 | |
| GSE77861 | AK9 | 221264 | 1552299_at | -0.2928 | 0.0020 | |
| SRP007169 | AK9 | 221264 | RNAseq | -2.4758 | 0.0000 | |
| SRP064894 | AK9 | 221264 | RNAseq | -0.9361 | 0.0000 | |
| SRP133303 | AK9 | 221264 | RNAseq | -0.4612 | 0.0342 | |
| SRP159526 | AK9 | 221264 | RNAseq | -0.7213 | 0.0062 | |
| SRP193095 | AK9 | 221264 | RNAseq | -0.4675 | 0.0020 | |
| SRP219564 | AK9 | 221264 | RNAseq | -1.0908 | 0.0280 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by AK9 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AK9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AK9 | 221264 | 3 | 3 | 24 | |
| GSE20123 | AK9 | 221264 | 3 | 2 | 25 | |
| GSE43470 | AK9 | 221264 | 3 | 1 | 39 | |
| GSE46452 | AK9 | 221264 | 2 | 11 | 46 | |
| GSE47630 | AK9 | 221264 | 9 | 4 | 27 | |
| GSE54993 | AK9 | 221264 | 3 | 2 | 65 | |
| GSE54994 | AK9 | 221264 | 8 | 8 | 37 | |
| GSE60625 | AK9 | 221264 | 0 | 2 | 9 | |
| GSE74703 | AK9 | 221264 | 2 | 1 | 33 | |
| GSE74704 | AK9 | 221264 | 1 | 0 | 19 | |
| TCGA | AK9 | 221264 | 6 | 24 | 66 |
Total number of gains: 40; Total number of losses: 58; Total Number of normals: 390.
Somatic mutations of AK9:
Generating mutation plots.
Highly correlated genes for AK9:
Showing top 20/1171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AK9 | EIF4E3 | 0.779812 | 6 | 0 | 6 |
| AK9 | SH3BGRL2 | 0.779765 | 6 | 0 | 6 |
| AK9 | SNORA68 | 0.771499 | 4 | 0 | 4 |
| AK9 | CAB39L | 0.769123 | 6 | 0 | 6 |
| AK9 | LMBRD1 | 0.765416 | 6 | 0 | 6 |
| AK9 | GPD1L | 0.761294 | 6 | 0 | 6 |
| AK9 | CALCOCO2 | 0.759615 | 6 | 0 | 6 |
| AK9 | GBP6 | 0.758144 | 4 | 0 | 4 |
| AK9 | EPB41L4A | 0.755201 | 4 | 0 | 4 |
| AK9 | RBM20 | 0.755105 | 3 | 0 | 3 |
| AK9 | KCNAB1 | 0.754726 | 5 | 0 | 5 |
| AK9 | KAT2B | 0.748738 | 6 | 0 | 6 |
| AK9 | DLG2 | 0.748471 | 6 | 0 | 6 |
| AK9 | FCHO2 | 0.743181 | 6 | 0 | 6 |
| AK9 | HBP1 | 0.741902 | 4 | 0 | 4 |
| AK9 | EPHX2 | 0.740761 | 6 | 0 | 6 |
| AK9 | SORT1 | 0.738088 | 6 | 0 | 6 |
| AK9 | ZDHHC13 | 0.735018 | 4 | 0 | 4 |
| AK9 | MPC1 | 0.733573 | 6 | 0 | 6 |
| AK9 | PAQR8 | 0.731887 | 6 | 0 | 6 |
For details and further investigation, click here
