| Full name: HLA complex group 22 (gene/pseudogene) | Alias Symbol: FLJ37114|PBMUCL2 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 285834 | HGNC ID: HGNC:27780 | Ensembl Gene: ENSG00000228789 | OMIM ID: 613918 |
| Drug and gene relationship at DGIdb | |||
Expression of HCG22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HCG22 | 285834 | 1560767_at | -1.8743 | 0.0331 | |
| GSE26886 | HCG22 | 285834 | 1560767_at | -1.9119 | 0.0000 | |
| GSE45670 | HCG22 | 285834 | 1560767_at | -2.3961 | 0.0002 | |
| GSE53622 | HCG22 | 285834 | 63523 | -3.8050 | 0.0000 | |
| GSE53624 | HCG22 | 285834 | 149201 | -4.5703 | 0.0000 | |
| GSE63941 | HCG22 | 285834 | 1560767_at | 0.2833 | 0.0739 | |
| GSE77861 | HCG22 | 285834 | 1560767_at | -1.1430 | 0.0017 | |
| SRP007169 | HCG22 | 285834 | RNAseq | -12.3131 | 0.0000 | |
| SRP008496 | HCG22 | 285834 | RNAseq | -6.9780 | 0.0000 | |
| SRP064894 | HCG22 | 285834 | RNAseq | -6.4783 | 0.0000 | |
| SRP133303 | HCG22 | 285834 | RNAseq | -6.8610 | 0.0000 | |
| SRP159526 | HCG22 | 285834 | RNAseq | -7.0467 | 0.0000 | |
| TCGA | HCG22 | 285834 | RNAseq | 0.0412 | 0.9573 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by HCG22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HCG22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HCG22 | 285834 | 5 | 1 | 24 | |
| GSE20123 | HCG22 | 285834 | 5 | 1 | 24 | |
| GSE43470 | HCG22 | 285834 | 5 | 1 | 37 | |
| GSE46452 | HCG22 | 285834 | 1 | 10 | 48 | |
| GSE47630 | HCG22 | 285834 | 7 | 3 | 30 | |
| GSE54993 | HCG22 | 285834 | 2 | 1 | 67 | |
| GSE54994 | HCG22 | 285834 | 11 | 4 | 38 | |
| GSE60625 | HCG22 | 285834 | 0 | 1 | 10 | |
| GSE74703 | HCG22 | 285834 | 5 | 0 | 31 | |
| GSE74704 | HCG22 | 285834 | 2 | 0 | 18 | |
| TCGA | HCG22 | 285834 | 17 | 16 | 63 |
Total number of gains: 60; Total number of losses: 38; Total Number of normals: 390.
Somatic mutations of HCG22:
Generating mutation plots.
Highly correlated genes for HCG22:
Showing top 20/1377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HCG22 | ENDOU | 0.884286 | 6 | 0 | 6 |
| HCG22 | CRISP3 | 0.880624 | 6 | 0 | 6 |
| HCG22 | UPK1A | 0.877617 | 6 | 0 | 6 |
| HCG22 | UBL3 | 0.868401 | 6 | 0 | 6 |
| HCG22 | PSCA | 0.861957 | 4 | 0 | 4 |
| HCG22 | APOA1 | 0.860409 | 3 | 0 | 3 |
| HCG22 | RANBP9 | 0.85931 | 6 | 0 | 6 |
| HCG22 | SH3BGRL2 | 0.858815 | 6 | 0 | 6 |
| HCG22 | MUC21 | 0.856941 | 3 | 0 | 3 |
| HCG22 | VSIG10L | 0.853647 | 6 | 0 | 6 |
| HCG22 | SLC16A6 | 0.852387 | 6 | 0 | 6 |
| HCG22 | KRT78 | 0.850434 | 7 | 0 | 7 |
| HCG22 | ANXA9 | 0.849869 | 6 | 0 | 6 |
| HCG22 | RAET1E | 0.849541 | 6 | 0 | 6 |
| HCG22 | SLC46A2 | 0.84677 | 6 | 0 | 6 |
| HCG22 | MAPK3 | 0.845621 | 6 | 0 | 6 |
| HCG22 | EPB41L3 | 0.844409 | 6 | 0 | 6 |
| HCG22 | DEGS2 | 0.839388 | 6 | 0 | 6 |
| HCG22 | FLG | 0.838737 | 6 | 0 | 6 |
| HCG22 | CCNG2 | 0.838647 | 6 | 0 | 6 |
For details and further investigation, click here
