| Full name: TPD52 like 1 | Alias Symbol: D53|hD53 | ||
| Type: protein-coding gene | Cytoband: 6q22-q23 | ||
| Entrez ID: 7164 | HGNC ID: HGNC:12006 | Ensembl Gene: ENSG00000111907 | OMIM ID: 604069 |
| Drug and gene relationship at DGIdb | |||
Expression of TPD52L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPD52L1 | 7164 | 203786_s_at | -0.7908 | 0.1149 | |
| GSE20347 | TPD52L1 | 7164 | 203786_s_at | -1.0563 | 0.0000 | |
| GSE23400 | TPD52L1 | 7164 | 203786_s_at | -0.6595 | 0.0000 | |
| GSE26886 | TPD52L1 | 7164 | 203786_s_at | -0.6149 | 0.0071 | |
| GSE29001 | TPD52L1 | 7164 | 203786_s_at | -0.9047 | 0.0042 | |
| GSE38129 | TPD52L1 | 7164 | 203786_s_at | -0.4956 | 0.1505 | |
| GSE45670 | TPD52L1 | 7164 | 203786_s_at | -0.4290 | 0.0286 | |
| GSE53622 | TPD52L1 | 7164 | 73092 | -1.0949 | 0.0000 | |
| GSE53624 | TPD52L1 | 7164 | 73092 | -1.3271 | 0.0000 | |
| GSE63941 | TPD52L1 | 7164 | 203786_s_at | 1.7689 | 0.0174 | |
| GSE77861 | TPD52L1 | 7164 | 203786_s_at | -0.6153 | 0.0071 | |
| GSE97050 | TPD52L1 | 7164 | A_33_P3398065 | 0.3562 | 0.5375 | |
| SRP007169 | TPD52L1 | 7164 | RNAseq | -1.4941 | 0.0036 | |
| SRP008496 | TPD52L1 | 7164 | RNAseq | -1.4338 | 0.0000 | |
| SRP064894 | TPD52L1 | 7164 | RNAseq | -1.4318 | 0.0000 | |
| SRP133303 | TPD52L1 | 7164 | RNAseq | -1.2569 | 0.0000 | |
| SRP159526 | TPD52L1 | 7164 | RNAseq | -0.7871 | 0.0632 | |
| SRP193095 | TPD52L1 | 7164 | RNAseq | -1.3220 | 0.0000 | |
| SRP219564 | TPD52L1 | 7164 | RNAseq | -1.6330 | 0.0191 | |
| TCGA | TPD52L1 | 7164 | RNAseq | 0.0647 | 0.5167 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by TPD52L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TPD52L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPD52L1 | 7164 | 2 | 4 | 24 | |
| GSE20123 | TPD52L1 | 7164 | 3 | 3 | 24 | |
| GSE43470 | TPD52L1 | 7164 | 5 | 0 | 38 | |
| GSE46452 | TPD52L1 | 7164 | 2 | 11 | 46 | |
| GSE47630 | TPD52L1 | 7164 | 9 | 4 | 27 | |
| GSE54993 | TPD52L1 | 7164 | 3 | 3 | 64 | |
| GSE54994 | TPD52L1 | 7164 | 8 | 8 | 37 | |
| GSE60625 | TPD52L1 | 7164 | 0 | 1 | 10 | |
| GSE74703 | TPD52L1 | 7164 | 4 | 0 | 32 | |
| GSE74704 | TPD52L1 | 7164 | 0 | 1 | 19 | |
| TCGA | TPD52L1 | 7164 | 14 | 18 | 64 |
Total number of gains: 50; Total number of losses: 53; Total Number of normals: 385.
Somatic mutations of TPD52L1:
Generating mutation plots.
Highly correlated genes for TPD52L1:
Showing top 20/1218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPD52L1 | NIPAL1 | 0.766475 | 3 | 0 | 3 |
| TPD52L1 | ARAP2 | 0.765942 | 3 | 0 | 3 |
| TPD52L1 | LTA4H | 0.759621 | 3 | 0 | 3 |
| TPD52L1 | DSG3 | 0.748728 | 10 | 0 | 10 |
| TPD52L1 | MIR205HG | 0.747978 | 3 | 0 | 3 |
| TPD52L1 | SYTL1 | 0.746977 | 8 | 0 | 7 |
| TPD52L1 | SFTA2 | 0.743827 | 4 | 0 | 4 |
| TPD52L1 | PITX1 | 0.742763 | 11 | 0 | 11 |
| TPD52L1 | S100A16 | 0.740151 | 7 | 0 | 7 |
| TPD52L1 | RAB25 | 0.736745 | 13 | 0 | 11 |
| TPD52L1 | CYSRT1 | 0.735329 | 6 | 0 | 6 |
| TPD52L1 | C19orf33 | 0.734147 | 6 | 0 | 6 |
| TPD52L1 | UPK3B | 0.730163 | 3 | 0 | 3 |
| TPD52L1 | LCN6 | 0.728956 | 3 | 0 | 3 |
| TPD52L1 | SMAGP | 0.727684 | 12 | 0 | 10 |
| TPD52L1 | GRHL1 | 0.725898 | 8 | 0 | 8 |
| TPD52L1 | TMEM154 | 0.725859 | 7 | 0 | 6 |
| TPD52L1 | EVPL | 0.725808 | 12 | 0 | 12 |
| TPD52L1 | CKMT1A | 0.72555 | 3 | 0 | 3 |
| TPD52L1 | ARHGAP27 | 0.724706 | 8 | 0 | 8 |
For details and further investigation, click here
