| Full name: nebulette | Alias Symbol: LASP2|LNEBL | ||
| Type: protein-coding gene | Cytoband: 10p12.31 | ||
| Entrez ID: 10529 | HGNC ID: HGNC:16932 | Ensembl Gene: ENSG00000078114 | OMIM ID: 605491 |
| Drug and gene relationship at DGIdb | |||
Expression of NEBL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEBL | 10529 | 203961_at | -1.6658 | 0.1276 | |
| GSE20347 | NEBL | 10529 | 203961_at | -2.7423 | 0.0000 | |
| GSE23400 | NEBL | 10529 | 203961_at | -1.3975 | 0.0000 | |
| GSE26886 | NEBL | 10529 | 203961_at | -2.1192 | 0.0000 | |
| GSE29001 | NEBL | 10529 | 203961_at | -2.1957 | 0.0006 | |
| GSE38129 | NEBL | 10529 | 203961_at | -1.8036 | 0.0003 | |
| GSE45670 | NEBL | 10529 | 203961_at | -1.1020 | 0.0106 | |
| GSE53622 | NEBL | 10529 | 27675 | -1.8538 | 0.0000 | |
| GSE53624 | NEBL | 10529 | 27675 | -2.3224 | 0.0000 | |
| GSE63941 | NEBL | 10529 | 203961_at | 3.9130 | 0.0056 | |
| GSE77861 | NEBL | 10529 | 203961_at | -2.0894 | 0.0008 | |
| GSE97050 | NEBL | 10529 | A_33_P3244013 | 0.1260 | 0.6569 | |
| SRP007169 | NEBL | 10529 | RNAseq | -2.0513 | 0.0011 | |
| SRP008496 | NEBL | 10529 | RNAseq | -2.3558 | 0.0000 | |
| SRP064894 | NEBL | 10529 | RNAseq | -2.3225 | 0.0000 | |
| SRP133303 | NEBL | 10529 | RNAseq | -1.7938 | 0.0000 | |
| SRP159526 | NEBL | 10529 | RNAseq | -1.8265 | 0.0005 | |
| SRP193095 | NEBL | 10529 | RNAseq | -2.1768 | 0.0000 | |
| SRP219564 | NEBL | 10529 | RNAseq | -2.3812 | 0.0076 | |
| TCGA | NEBL | 10529 | RNAseq | -0.0268 | 0.8489 |
Upregulated datasets: 1; Downregulated datasets: 16.
Survival by NEBL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEBL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEBL | 10529 | 5 | 8 | 17 | |
| GSE20123 | NEBL | 10529 | 5 | 7 | 18 | |
| GSE43470 | NEBL | 10529 | 3 | 4 | 36 | |
| GSE46452 | NEBL | 10529 | 1 | 14 | 44 | |
| GSE47630 | NEBL | 10529 | 5 | 15 | 20 | |
| GSE54993 | NEBL | 10529 | 10 | 0 | 60 | |
| GSE54994 | NEBL | 10529 | 3 | 9 | 41 | |
| GSE60625 | NEBL | 10529 | 0 | 0 | 11 | |
| GSE74703 | NEBL | 10529 | 2 | 2 | 32 | |
| GSE74704 | NEBL | 10529 | 0 | 6 | 14 | |
| TCGA | NEBL | 10529 | 18 | 27 | 51 |
Total number of gains: 52; Total number of losses: 92; Total Number of normals: 344.
Somatic mutations of NEBL:
Generating mutation plots.
Highly correlated genes for NEBL:
Showing top 20/1020 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEBL | SCNN1B | 0.811999 | 11 | 0 | 11 |
| NEBL | NCCRP1 | 0.810193 | 3 | 0 | 3 |
| NEBL | EPS8L2 | 0.809994 | 11 | 0 | 11 |
| NEBL | SFTA2 | 0.809144 | 4 | 0 | 4 |
| NEBL | MGST2 | 0.806477 | 10 | 0 | 10 |
| NEBL | PLD1 | 0.806345 | 10 | 0 | 10 |
| NEBL | CHP1 | 0.802733 | 10 | 0 | 10 |
| NEBL | SNORA68 | 0.80251 | 4 | 0 | 4 |
| NEBL | EPHA1 | 0.800182 | 12 | 0 | 12 |
| NEBL | CLIC3 | 0.799513 | 9 | 0 | 9 |
| NEBL | SPNS2 | 0.794605 | 4 | 0 | 4 |
| NEBL | ACPP | 0.791702 | 13 | 0 | 11 |
| NEBL | TTC9 | 0.790563 | 11 | 0 | 10 |
| NEBL | EVPL | 0.789673 | 12 | 0 | 12 |
| NEBL | GDPD3 | 0.788907 | 11 | 0 | 11 |
| NEBL | ENDOU | 0.788057 | 11 | 0 | 11 |
| NEBL | ZNF823 | 0.787881 | 6 | 0 | 6 |
| NEBL | ANXA9 | 0.784519 | 10 | 0 | 10 |
| NEBL | TECR | 0.782037 | 11 | 0 | 11 |
| NEBL | SPAG17 | 0.780399 | 5 | 0 | 5 |
For details and further investigation, click here
