DCAF16

 

Full name: DDB1 and CUL4 associated factor 16 Alias Symbol: FLJ20280
Type: protein-coding gene Cytoband: 4p15.31
Entrez ID: 54876 HGNC ID: HGNC:25987 Ensembl Gene: ENSG00000163257 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of DCAF16:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DCAF16 54876 228106_at 0.4231 0.4326
GSE20347 DCAF16 54876 219717_at -0.2949 0.0085
GSE23400 DCAF16 54876 219717_at -0.0730 0.4072
GSE26886 DCAF16 54876 228106_at 0.2253 0.5434
GSE29001 DCAF16 54876 219717_at 0.0062 0.9857
GSE38129 DCAF16 54876 219717_at -0.1666 0.5409
GSE45670 DCAF16 54876 228106_at -0.1600 0.4321
GSE53622 DCAF16 54876 35509 0.2114 0.0055
GSE53624 DCAF16 54876 35509 0.1519 0.0544
GSE63941 DCAF16 54876 228106_at -0.2396 0.6812
GSE77861 DCAF16 54876 228106_at 0.5951 0.0540
GSE97050 DCAF16 54876 A_33_P3296308 -0.5687 0.0887
SRP007169 DCAF16 54876 RNAseq 0.9843 0.0404
SRP008496 DCAF16 54876 RNAseq 1.1308 0.0000
SRP064894 DCAF16 54876 RNAseq -0.0551 0.7945
SRP133303 DCAF16 54876 RNAseq 0.0900 0.4041
SRP159526 DCAF16 54876 RNAseq 0.2709 0.3863
SRP193095 DCAF16 54876 RNAseq 0.0366 0.6357
SRP219564 DCAF16 54876 RNAseq 0.0750 0.7686
TCGA DCAF16 54876 RNAseq -0.0607 0.2958

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DCAF16 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DCAF16:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DCAF16 54876 0 18 12
GSE20123 DCAF16 54876 0 18 12
GSE43470 DCAF16 54876 1 15 27
GSE46452 DCAF16 54876 1 36 22
GSE47630 DCAF16 54876 1 19 20
GSE54993 DCAF16 54876 9 0 61
GSE54994 DCAF16 54876 4 12 37
GSE60625 DCAF16 54876 0 0 11
GSE74703 DCAF16 54876 1 13 22
GSE74704 DCAF16 54876 0 11 9
TCGA DCAF16 54876 9 48 39

Total number of gains: 26; Total number of losses: 190; Total Number of normals: 272.  

 

Somatic mutations of DCAF16:

 

Generating mutation plots.

 

Highly correlated genes for DCAF16:

 

Showing top 20/354 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DCAF16MLEC0.82851303
DCAF16MRPS90.811966303
DCAF16NOM10.802507303
DCAF16ALKBH60.769534303
DCAF16CBFA2T20.762107303
DCAF16LMLN0.756751303
DCAF16TAF150.749948303
DCAF16NIPAL30.747121303
DCAF16PTPN110.746638303
DCAF16DDX60.746205303
DCAF16AZIN10.74426303
DCAF16FANCL0.743219504
DCAF16GNA110.742199303
DCAF16GOLGA30.741624303
DCAF16CPNE80.733529303
DCAF16PHF20.730286404
DCAF16METAP1D0.725061404
DCAF16SPAST0.725036303
DCAF16RNF40.722277303
DCAF16PLCG10.716302303

For details and further investigation, click here