| Full name: ribosomal protein L39 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q27.3 | ||
| Entrez ID: 116832 | HGNC ID: HGNC:17094 | Ensembl Gene: ENSG00000163923 | OMIM ID: 607547 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPL39L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL39L | 116832 | 210115_at | 1.4850 | 0.0696 | |
| GSE20347 | RPL39L | 116832 | 210115_at | 1.7429 | 0.0000 | |
| GSE23400 | RPL39L | 116832 | 210115_at | 0.9230 | 0.0000 | |
| GSE26886 | RPL39L | 116832 | 210115_at | 1.5942 | 0.0000 | |
| GSE29001 | RPL39L | 116832 | 210115_at | 1.3838 | 0.0012 | |
| GSE38129 | RPL39L | 116832 | 210115_at | 1.9809 | 0.0000 | |
| GSE45670 | RPL39L | 116832 | 210115_at | 1.5943 | 0.0002 | |
| GSE53622 | RPL39L | 116832 | 52179 | 1.7215 | 0.0000 | |
| GSE53624 | RPL39L | 116832 | 43869 | 1.5383 | 0.0000 | |
| GSE63941 | RPL39L | 116832 | 210115_at | 2.2508 | 0.0290 | |
| GSE77861 | RPL39L | 116832 | 210115_at | 1.4467 | 0.0009 | |
| GSE97050 | RPL39L | 116832 | A_23_P29594 | 1.0273 | 0.1883 | |
| SRP007169 | RPL39L | 116832 | RNAseq | 2.5215 | 0.0000 | |
| SRP008496 | RPL39L | 116832 | RNAseq | 2.9274 | 0.0000 | |
| SRP064894 | RPL39L | 116832 | RNAseq | 1.7307 | 0.0000 | |
| SRP133303 | RPL39L | 116832 | RNAseq | 2.3585 | 0.0000 | |
| SRP159526 | RPL39L | 116832 | RNAseq | 2.6469 | 0.0000 | |
| SRP193095 | RPL39L | 116832 | RNAseq | 1.9753 | 0.0000 | |
| SRP219564 | RPL39L | 116832 | RNAseq | 2.1264 | 0.0084 | |
| TCGA | RPL39L | 116832 | RNAseq | 1.2807 | 0.0000 |
Upregulated datasets: 17; Downregulated datasets: 0.
Survival by RPL39L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL39L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL39L | 116832 | 24 | 0 | 6 | |
| GSE20123 | RPL39L | 116832 | 24 | 0 | 6 | |
| GSE43470 | RPL39L | 116832 | 23 | 1 | 19 | |
| GSE46452 | RPL39L | 116832 | 19 | 1 | 39 | |
| GSE47630 | RPL39L | 116832 | 27 | 2 | 11 | |
| GSE54993 | RPL39L | 116832 | 1 | 19 | 50 | |
| GSE54994 | RPL39L | 116832 | 39 | 0 | 14 | |
| GSE60625 | RPL39L | 116832 | 0 | 6 | 5 | |
| GSE74703 | RPL39L | 116832 | 20 | 1 | 15 | |
| GSE74704 | RPL39L | 116832 | 16 | 0 | 4 | |
| TCGA | RPL39L | 116832 | 77 | 0 | 19 |
Total number of gains: 270; Total number of losses: 30; Total Number of normals: 188.
Somatic mutations of RPL39L:
Generating mutation plots.
Highly correlated genes for RPL39L:
Showing top 20/2122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL39L | GOLM1 | 0.808535 | 5 | 0 | 5 |
| RPL39L | CD276 | 0.807847 | 4 | 0 | 4 |
| RPL39L | RFC4 | 0.794802 | 13 | 0 | 12 |
| RPL39L | BRCA1 | 0.772565 | 11 | 0 | 11 |
| RPL39L | MYBL2 | 0.769876 | 12 | 0 | 12 |
| RPL39L | CKS1B | 0.766593 | 13 | 0 | 13 |
| RPL39L | KNSTRN | 0.765074 | 7 | 0 | 7 |
| RPL39L | MCM2 | 0.763701 | 12 | 0 | 11 |
| RPL39L | TTL | 0.761686 | 7 | 0 | 7 |
| RPL39L | NCAPH | 0.761473 | 9 | 0 | 9 |
| RPL39L | EME1 | 0.760476 | 6 | 0 | 6 |
| RPL39L | UBE2T | 0.754066 | 9 | 0 | 8 |
| RPL39L | CENPF | 0.753027 | 11 | 0 | 11 |
| RPL39L | CMSS1 | 0.752965 | 6 | 0 | 6 |
| RPL39L | PLEKHA3 | 0.751452 | 3 | 0 | 3 |
| RPL39L | HOXB7 | 0.749397 | 12 | 0 | 12 |
| RPL39L | NOP58 | 0.74682 | 6 | 0 | 6 |
| RPL39L | ZCCHC7 | 0.746 | 3 | 0 | 3 |
| RPL39L | SNAP47 | 0.745552 | 3 | 0 | 3 |
| RPL39L | MRPL47 | 0.744984 | 8 | 0 | 7 |
For details and further investigation, click here
