| Full name: LIM homeobox transcription factor 1 beta | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 4010 | HGNC ID: HGNC:6654 | Ensembl Gene: ENSG00000136944 | OMIM ID: 602575 |
| Drug and gene relationship at DGIdb | |||
Expression of LMX1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMX1B | 4010 | 208487_at | -0.0645 | 0.8271 | |
| GSE20347 | LMX1B | 4010 | 208487_at | 0.0939 | 0.3984 | |
| GSE23400 | LMX1B | 4010 | 208487_at | -0.1185 | 0.0060 | |
| GSE26886 | LMX1B | 4010 | 208487_at | 0.1715 | 0.1860 | |
| GSE29001 | LMX1B | 4010 | 208487_at | -0.1795 | 0.3126 | |
| GSE38129 | LMX1B | 4010 | 208487_at | -0.0162 | 0.9024 | |
| GSE45670 | LMX1B | 4010 | 208487_at | -0.0533 | 0.5878 | |
| GSE53622 | LMX1B | 4010 | 129633 | 0.5009 | 0.0000 | |
| GSE53624 | LMX1B | 4010 | 129633 | 0.5973 | 0.0000 | |
| GSE63941 | LMX1B | 4010 | 208487_at | 0.4343 | 0.0405 | |
| GSE77861 | LMX1B | 4010 | 208487_at | -0.0214 | 0.8473 | |
| GSE97050 | LMX1B | 4010 | A_33_P3350643 | -0.4608 | 0.1678 | |
| SRP133303 | LMX1B | 4010 | RNAseq | 1.3207 | 0.0000 | |
| SRP159526 | LMX1B | 4010 | RNAseq | 4.4775 | 0.0000 | |
| SRP193095 | LMX1B | 4010 | RNAseq | 1.4693 | 0.0000 | |
| SRP219564 | LMX1B | 4010 | RNAseq | 2.3371 | 0.0000 | |
| TCGA | LMX1B | 4010 | RNAseq | 1.8020 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by LMX1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMX1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMX1B | 4010 | 5 | 9 | 16 | |
| GSE20123 | LMX1B | 4010 | 5 | 9 | 16 | |
| GSE43470 | LMX1B | 4010 | 7 | 5 | 31 | |
| GSE46452 | LMX1B | 4010 | 6 | 13 | 40 | |
| GSE47630 | LMX1B | 4010 | 3 | 16 | 21 | |
| GSE54993 | LMX1B | 4010 | 3 | 3 | 64 | |
| GSE54994 | LMX1B | 4010 | 12 | 8 | 33 | |
| GSE60625 | LMX1B | 4010 | 0 | 0 | 11 | |
| GSE74703 | LMX1B | 4010 | 6 | 3 | 27 | |
| GSE74704 | LMX1B | 4010 | 2 | 7 | 11 | |
| TCGA | LMX1B | 4010 | 27 | 25 | 44 |
Total number of gains: 76; Total number of losses: 98; Total Number of normals: 314.
Somatic mutations of LMX1B:
Generating mutation plots.
Highly correlated genes for LMX1B:
Showing top 20/791 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMX1B | TRAPPC9 | 0.770261 | 3 | 0 | 3 |
| LMX1B | ESPNL | 0.721786 | 3 | 0 | 3 |
| LMX1B | BLACE | 0.720423 | 3 | 0 | 3 |
| LMX1B | C2CD4D | 0.709625 | 3 | 0 | 3 |
| LMX1B | CER1 | 0.705296 | 4 | 0 | 4 |
| LMX1B | ABCC6 | 0.703099 | 3 | 0 | 3 |
| LMX1B | LHB | 0.701723 | 3 | 0 | 3 |
| LMX1B | MS4A18 | 0.692434 | 3 | 0 | 3 |
| LMX1B | IFNA4 | 0.692321 | 5 | 0 | 5 |
| LMX1B | TMEM151B | 0.691465 | 5 | 0 | 5 |
| LMX1B | MRGPRG | 0.6895 | 3 | 0 | 3 |
| LMX1B | DDX51 | 0.688671 | 3 | 0 | 3 |
| LMX1B | HSF4 | 0.680268 | 5 | 0 | 4 |
| LMX1B | ACSM2A | 0.672581 | 3 | 0 | 3 |
| LMX1B | TNFRSF14 | 0.672417 | 3 | 0 | 3 |
| LMX1B | NKAIN4 | 0.671003 | 3 | 0 | 3 |
| LMX1B | FBRSL1 | 0.670982 | 3 | 0 | 3 |
| LMX1B | CLCN1 | 0.669708 | 4 | 0 | 3 |
| LMX1B | CARTPT | 0.667425 | 3 | 0 | 3 |
| LMX1B | SFN | 0.665886 | 3 | 0 | 3 |
For details and further investigation, click here
