| Full name: TNF receptor superfamily member 14 | Alias Symbol: HVEM|ATAR|TR2|LIGHTR|HVEA|CD270 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 8764 | HGNC ID: HGNC:11912 | Ensembl Gene: ENSG00000157873 | OMIM ID: 602746 |
| Drug and gene relationship at DGIdb | |||
TNFRSF14 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05168 | Herpes simplex infection |
Expression of TNFRSF14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFRSF14 | 8764 | 209354_at | -0.0115 | 0.9827 | |
| GSE20347 | TNFRSF14 | 8764 | 209354_at | -0.1961 | 0.2658 | |
| GSE23400 | TNFRSF14 | 8764 | 209354_at | -0.1143 | 0.0647 | |
| GSE26886 | TNFRSF14 | 8764 | 209354_at | 0.1171 | 0.6395 | |
| GSE29001 | TNFRSF14 | 8764 | 209354_at | -0.0988 | 0.7301 | |
| GSE38129 | TNFRSF14 | 8764 | 209354_at | -0.3532 | 0.0300 | |
| GSE45670 | TNFRSF14 | 8764 | 209354_at | -0.1062 | 0.5826 | |
| GSE53622 | TNFRSF14 | 8764 | 99634 | 0.2726 | 0.0026 | |
| GSE53624 | TNFRSF14 | 8764 | 20846 | -0.3094 | 0.0001 | |
| GSE63941 | TNFRSF14 | 8764 | 209354_at | -0.9332 | 0.0133 | |
| GSE77861 | TNFRSF14 | 8764 | 209354_at | -0.2587 | 0.0439 | |
| GSE97050 | TNFRSF14 | 8764 | A_33_P3286302 | -0.0333 | 0.8853 | |
| SRP007169 | TNFRSF14 | 8764 | RNAseq | -0.5854 | 0.3720 | |
| SRP008496 | TNFRSF14 | 8764 | RNAseq | -0.8191 | 0.0552 | |
| SRP064894 | TNFRSF14 | 8764 | RNAseq | 0.1799 | 0.5269 | |
| SRP133303 | TNFRSF14 | 8764 | RNAseq | -0.3498 | 0.0904 | |
| SRP159526 | TNFRSF14 | 8764 | RNAseq | -0.3234 | 0.3776 | |
| SRP193095 | TNFRSF14 | 8764 | RNAseq | -0.0394 | 0.8943 | |
| SRP219564 | TNFRSF14 | 8764 | RNAseq | 0.0145 | 0.9652 | |
| TCGA | TNFRSF14 | 8764 | RNAseq | -0.3256 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNFRSF14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFRSF14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFRSF14 | 8764 | 3 | 6 | 21 | |
| GSE20123 | TNFRSF14 | 8764 | 3 | 5 | 22 | |
| GSE43470 | TNFRSF14 | 8764 | 2 | 5 | 36 | |
| GSE46452 | TNFRSF14 | 8764 | 7 | 1 | 51 | |
| GSE47630 | TNFRSF14 | 8764 | 8 | 4 | 28 | |
| GSE54993 | TNFRSF14 | 8764 | 3 | 2 | 65 | |
| GSE54994 | TNFRSF14 | 8764 | 15 | 2 | 36 | |
| GSE60625 | TNFRSF14 | 8764 | 0 | 0 | 11 | |
| GSE74703 | TNFRSF14 | 8764 | 2 | 3 | 31 | |
| GSE74704 | TNFRSF14 | 8764 | 3 | 0 | 17 | |
| TCGA | TNFRSF14 | 8764 | 14 | 20 | 62 |
Total number of gains: 60; Total number of losses: 48; Total Number of normals: 380.
Somatic mutations of TNFRSF14:
Generating mutation plots.
Highly correlated genes for TNFRSF14:
Showing top 20/189 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFRSF14 | SLC22A31 | 0.815922 | 4 | 0 | 4 |
| TNFRSF14 | SLC26A1 | 0.810322 | 3 | 0 | 3 |
| TNFRSF14 | C7orf61 | 0.767173 | 3 | 0 | 3 |
| TNFRSF14 | PNMA6A | 0.765002 | 3 | 0 | 3 |
| TNFRSF14 | KLF17 | 0.757555 | 3 | 0 | 3 |
| TNFRSF14 | SYT3 | 0.755982 | 3 | 0 | 3 |
| TNFRSF14 | VHL | 0.755854 | 3 | 0 | 3 |
| TNFRSF14 | MFSD6L | 0.755834 | 3 | 0 | 3 |
| TNFRSF14 | C19orf44 | 0.728322 | 4 | 0 | 3 |
| TNFRSF14 | KCTD19 | 0.726247 | 3 | 0 | 3 |
| TNFRSF14 | KRT35 | 0.726194 | 4 | 0 | 4 |
| TNFRSF14 | KRTAP2-1 | 0.714578 | 4 | 0 | 3 |
| TNFRSF14 | SNAI1 | 0.711611 | 3 | 0 | 3 |
| TNFRSF14 | CIB3 | 0.708997 | 4 | 0 | 3 |
| TNFRSF14 | ANKDD1A | 0.708977 | 4 | 0 | 3 |
| TNFRSF14 | CDH4 | 0.707548 | 3 | 0 | 3 |
| TNFRSF14 | GJD4 | 0.706324 | 4 | 0 | 3 |
| TNFRSF14 | PNPLA7 | 0.704513 | 5 | 0 | 4 |
| TNFRSF14 | GNL1 | 0.702863 | 3 | 0 | 3 |
| TNFRSF14 | LACRT | 0.702678 | 3 | 0 | 3 |
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