| Full name: DEAD-box helicase 51 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 317781 | HGNC ID: HGNC:20082 | Ensembl Gene: ENSG00000185163 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX51:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX51 | 317781 | 1554085_at | 0.6212 | 0.2824 | |
| GSE20347 | DDX51 | 317781 | 214968_at | -0.0512 | 0.5652 | |
| GSE23400 | DDX51 | 317781 | 214968_at | -0.0768 | 0.0395 | |
| GSE26886 | DDX51 | 317781 | 1554085_at | 0.5754 | 0.0048 | |
| GSE29001 | DDX51 | 317781 | 214968_at | -0.3044 | 0.0661 | |
| GSE38129 | DDX51 | 317781 | 214968_at | -0.1405 | 0.1682 | |
| GSE45670 | DDX51 | 317781 | 1554085_at | 0.3112 | 0.0068 | |
| GSE53622 | DDX51 | 317781 | 93157 | 0.0736 | 0.1542 | |
| GSE53624 | DDX51 | 317781 | 93157 | 0.0731 | 0.1885 | |
| GSE63941 | DDX51 | 317781 | 1554085_at | 0.2112 | 0.4546 | |
| GSE77861 | DDX51 | 317781 | 214968_at | -0.1353 | 0.1063 | |
| GSE97050 | DDX51 | 317781 | A_33_P3372886 | 0.0873 | 0.7743 | |
| SRP007169 | DDX51 | 317781 | RNAseq | 0.6270 | 0.2285 | |
| SRP008496 | DDX51 | 317781 | RNAseq | 0.9114 | 0.0238 | |
| SRP064894 | DDX51 | 317781 | RNAseq | 0.2106 | 0.1494 | |
| SRP133303 | DDX51 | 317781 | RNAseq | 0.0581 | 0.6984 | |
| SRP159526 | DDX51 | 317781 | RNAseq | 0.5229 | 0.2026 | |
| SRP193095 | DDX51 | 317781 | RNAseq | 0.3771 | 0.0001 | |
| SRP219564 | DDX51 | 317781 | RNAseq | 0.2798 | 0.4615 | |
| TCGA | DDX51 | 317781 | RNAseq | -0.0220 | 0.6925 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX51 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX51:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX51 | 317781 | 4 | 5 | 21 | |
| GSE20123 | DDX51 | 317781 | 4 | 5 | 21 | |
| GSE43470 | DDX51 | 317781 | 3 | 3 | 37 | |
| GSE46452 | DDX51 | 317781 | 8 | 3 | 48 | |
| GSE47630 | DDX51 | 317781 | 9 | 3 | 28 | |
| GSE54993 | DDX51 | 317781 | 0 | 6 | 64 | |
| GSE54994 | DDX51 | 317781 | 4 | 8 | 41 | |
| GSE60625 | DDX51 | 317781 | 0 | 0 | 11 | |
| GSE74703 | DDX51 | 317781 | 2 | 3 | 31 | |
| GSE74704 | DDX51 | 317781 | 2 | 3 | 15 | |
| TCGA | DDX51 | 317781 | 22 | 15 | 59 |
Total number of gains: 58; Total number of losses: 54; Total Number of normals: 376.
Somatic mutations of DDX51:
Generating mutation plots.
Highly correlated genes for DDX51:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX51 | SLC4A5 | 0.747352 | 3 | 0 | 3 |
| DDX51 | POLR1B | 0.705467 | 4 | 0 | 4 |
| DDX51 | GATA1 | 0.695813 | 3 | 0 | 3 |
| DDX51 | TRMT10C | 0.6896 | 3 | 0 | 3 |
| DDX51 | LMX1B | 0.688671 | 3 | 0 | 3 |
| DDX51 | MZT2B | 0.686306 | 3 | 0 | 3 |
| DDX51 | ARFGAP1 | 0.685198 | 3 | 0 | 3 |
| DDX51 | SLC6A9 | 0.680125 | 3 | 0 | 3 |
| DDX51 | HAUS2 | 0.677967 | 3 | 0 | 3 |
| DDX51 | RBM17 | 0.673595 | 5 | 0 | 5 |
| DDX51 | NPPB | 0.663708 | 4 | 0 | 3 |
| DDX51 | SLC35E1 | 0.659029 | 5 | 0 | 4 |
| DDX51 | PINX1 | 0.656056 | 3 | 0 | 3 |
| DDX51 | ZNF160 | 0.650314 | 5 | 0 | 5 |
| DDX51 | XPNPEP3 | 0.648041 | 4 | 0 | 3 |
| DDX51 | MCHR1 | 0.645077 | 4 | 0 | 3 |
| DDX51 | ZNF786 | 0.640028 | 4 | 0 | 3 |
| DDX51 | CHD8 | 0.632092 | 3 | 0 | 3 |
| DDX51 | ATG2A | 0.628975 | 3 | 0 | 3 |
| DDX51 | TBX4 | 0.62856 | 4 | 0 | 3 |
For details and further investigation, click here
