| Full name: LRP2 binding protein | Alias Symbol: DKFZp761O0113 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 55805 | HGNC ID: HGNC:25434 | Ensembl Gene: ENSG00000109771 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRP2BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRP2BP | 55805 | 207797_s_at | -0.3945 | 0.3757 | |
| GSE20347 | LRP2BP | 55805 | 207797_s_at | -0.0043 | 0.9619 | |
| GSE23400 | LRP2BP | 55805 | 207797_s_at | -0.2148 | 0.0000 | |
| GSE26886 | LRP2BP | 55805 | 207797_s_at | -0.2691 | 0.0817 | |
| GSE29001 | LRP2BP | 55805 | 207797_s_at | -0.1949 | 0.2477 | |
| GSE38129 | LRP2BP | 55805 | 207797_s_at | -0.2141 | 0.0055 | |
| GSE45670 | LRP2BP | 55805 | 207797_s_at | -0.1113 | 0.5705 | |
| GSE53622 | LRP2BP | 55805 | 46475 | -0.6290 | 0.0000 | |
| GSE53624 | LRP2BP | 55805 | 46475 | -0.7617 | 0.0000 | |
| GSE63941 | LRP2BP | 55805 | 207797_s_at | -0.0466 | 0.8734 | |
| GSE77861 | LRP2BP | 55805 | 207797_s_at | -0.0419 | 0.7760 | |
| SRP007169 | LRP2BP | 55805 | RNAseq | 0.6887 | 0.3874 | |
| SRP064894 | LRP2BP | 55805 | RNAseq | 0.2054 | 0.3625 | |
| SRP133303 | LRP2BP | 55805 | RNAseq | 0.0107 | 0.9604 | |
| SRP159526 | LRP2BP | 55805 | RNAseq | 0.1105 | 0.8190 | |
| SRP193095 | LRP2BP | 55805 | RNAseq | 0.0077 | 0.9572 | |
| SRP219564 | LRP2BP | 55805 | RNAseq | -0.5694 | 0.2498 | |
| TCGA | LRP2BP | 55805 | RNAseq | -0.6169 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRP2BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRP2BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRP2BP | 55805 | 3 | 11 | 16 | |
| GSE20123 | LRP2BP | 55805 | 3 | 11 | 16 | |
| GSE43470 | LRP2BP | 55805 | 1 | 13 | 29 | |
| GSE46452 | LRP2BP | 55805 | 1 | 36 | 22 | |
| GSE47630 | LRP2BP | 55805 | 0 | 22 | 18 | |
| GSE54993 | LRP2BP | 55805 | 10 | 0 | 60 | |
| GSE54994 | LRP2BP | 55805 | 2 | 12 | 39 | |
| GSE60625 | LRP2BP | 55805 | 0 | 0 | 11 | |
| GSE74703 | LRP2BP | 55805 | 1 | 10 | 25 | |
| GSE74704 | LRP2BP | 55805 | 1 | 5 | 14 | |
| TCGA | LRP2BP | 55805 | 11 | 32 | 53 |
Total number of gains: 33; Total number of losses: 152; Total Number of normals: 303.
Somatic mutations of LRP2BP:
Generating mutation plots.
Highly correlated genes for LRP2BP:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRP2BP | MBNL1-AS1 | 0.70132 | 3 | 0 | 3 |
| LRP2BP | IGSF1 | 0.675069 | 3 | 0 | 3 |
| LRP2BP | MTFR1L | 0.667285 | 4 | 0 | 4 |
| LRP2BP | TMOD1 | 0.663461 | 4 | 0 | 4 |
| LRP2BP | GALR1 | 0.658891 | 4 | 0 | 3 |
| LRP2BP | NEGR1 | 0.655349 | 3 | 0 | 3 |
| LRP2BP | CNGA3 | 0.654298 | 5 | 0 | 4 |
| LRP2BP | HOXA4 | 0.650636 | 3 | 0 | 3 |
| LRP2BP | STMN2 | 0.649746 | 4 | 0 | 3 |
| LRP2BP | FABP3 | 0.645158 | 5 | 0 | 4 |
| LRP2BP | SLC9B2 | 0.644704 | 3 | 0 | 3 |
| LRP2BP | C1QTNF2 | 0.633913 | 3 | 0 | 3 |
| LRP2BP | GDF10 | 0.63311 | 4 | 0 | 3 |
| LRP2BP | ZNF25 | 0.630866 | 4 | 0 | 3 |
| LRP2BP | MYOT | 0.630758 | 5 | 0 | 4 |
| LRP2BP | PPP1R1A | 0.625612 | 6 | 0 | 5 |
| LRP2BP | WSCD2 | 0.625572 | 5 | 0 | 3 |
| LRP2BP | ZMYND11 | 0.624604 | 4 | 0 | 3 |
| LRP2BP | FAM124A | 0.619883 | 4 | 0 | 3 |
| LRP2BP | PABPC5 | 0.618321 | 3 | 0 | 3 |
For details and further investigation, click here
