| Full name: galanin receptor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 18q23 | ||
| Entrez ID: 2587 | HGNC ID: HGNC:4132 | Ensembl Gene: ENSG00000166573 | OMIM ID: 600377 |
| Drug and gene relationship at DGIdb | |||
Expression of GALR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALR1 | 2587 | 220821_at | -0.1047 | 0.6110 | |
| GSE20347 | GALR1 | 2587 | 220821_at | -0.0596 | 0.4230 | |
| GSE23400 | GALR1 | 2587 | 220821_at | -0.0598 | 0.0156 | |
| GSE26886 | GALR1 | 2587 | 220821_at | -0.0669 | 0.4608 | |
| GSE29001 | GALR1 | 2587 | 220821_at | -0.0219 | 0.8737 | |
| GSE38129 | GALR1 | 2587 | 220821_at | -0.0891 | 0.1175 | |
| GSE45670 | GALR1 | 2587 | 220821_at | -0.0074 | 0.9282 | |
| GSE53622 | GALR1 | 2587 | 156616 | -0.5514 | 0.0030 | |
| GSE53624 | GALR1 | 2587 | 156616 | -0.3748 | 0.0015 | |
| GSE63941 | GALR1 | 2587 | 220821_at | 0.1069 | 0.4631 | |
| GSE77861 | GALR1 | 2587 | 220821_at | -0.0701 | 0.3995 | |
| SRP064894 | GALR1 | 2587 | RNAseq | 0.2285 | 0.4279 | |
| SRP133303 | GALR1 | 2587 | RNAseq | -0.1122 | 0.3376 | |
| SRP159526 | GALR1 | 2587 | RNAseq | 0.7619 | 0.1256 | |
| SRP193095 | GALR1 | 2587 | RNAseq | 0.0980 | 0.4971 | |
| SRP219564 | GALR1 | 2587 | RNAseq | 0.2121 | 0.6767 | |
| TCGA | GALR1 | 2587 | RNAseq | -3.0175 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GALR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALR1 | 2587 | 0 | 11 | 19 | |
| GSE20123 | GALR1 | 2587 | 0 | 11 | 19 | |
| GSE43470 | GALR1 | 2587 | 0 | 10 | 33 | |
| GSE46452 | GALR1 | 2587 | 1 | 26 | 32 | |
| GSE47630 | GALR1 | 2587 | 5 | 22 | 13 | |
| GSE54993 | GALR1 | 2587 | 9 | 0 | 61 | |
| GSE54994 | GALR1 | 2587 | 1 | 18 | 34 | |
| GSE60625 | GALR1 | 2587 | 0 | 4 | 7 | |
| GSE74703 | GALR1 | 2587 | 0 | 8 | 28 | |
| GSE74704 | GALR1 | 2587 | 0 | 9 | 11 | |
| TCGA | GALR1 | 2587 | 7 | 47 | 42 |
Total number of gains: 23; Total number of losses: 166; Total Number of normals: 299.
Somatic mutations of GALR1:
Generating mutation plots.
Highly correlated genes for GALR1:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALR1 | APOBEC1 | 0.755424 | 3 | 0 | 3 |
| GALR1 | USP2 | 0.754974 | 3 | 0 | 3 |
| GALR1 | EBF2 | 0.713229 | 3 | 0 | 3 |
| GALR1 | GRIA1 | 0.712152 | 3 | 0 | 3 |
| GALR1 | APOBEC2 | 0.709888 | 3 | 0 | 3 |
| GALR1 | CEACAM21 | 0.709803 | 3 | 0 | 3 |
| GALR1 | MPP2 | 0.705388 | 4 | 0 | 4 |
| GALR1 | PDZD3 | 0.701492 | 3 | 0 | 3 |
| GALR1 | AGTR2 | 0.68795 | 4 | 0 | 3 |
| GALR1 | ADAM22 | 0.68708 | 3 | 0 | 3 |
| GALR1 | SLC26A3 | 0.679023 | 3 | 0 | 3 |
| GALR1 | SLC6A7 | 0.662167 | 3 | 0 | 3 |
| GALR1 | OR10H3 | 0.66125 | 4 | 0 | 3 |
| GALR1 | SCTR | 0.659247 | 3 | 0 | 3 |
| GALR1 | LRP2BP | 0.658891 | 4 | 0 | 3 |
| GALR1 | TNFRSF8 | 0.657444 | 4 | 0 | 4 |
| GALR1 | CYP19A1 | 0.654613 | 3 | 0 | 3 |
| GALR1 | TOB1-AS1 | 0.652722 | 3 | 0 | 3 |
| GALR1 | KCND3 | 0.65148 | 4 | 0 | 3 |
| GALR1 | C6 | 0.651297 | 5 | 0 | 3 |
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