IGSF1

 

Full name: immunoglobulin superfamily member 1 Alias Symbol: KIAA0364|IGDC1|IGCD1|INHBP|MGC75490|PGSF2
Type: protein-coding gene Cytoband: Xq25
Entrez ID: 3547 HGNC ID: HGNC:5948 Ensembl Gene: ENSG00000147255 OMIM ID: 300137
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of IGSF1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IGSF1 3547 207695_s_at -0.2471 0.4935
GSE20347 IGSF1 3547 207695_s_at 0.0043 0.9585
GSE23400 IGSF1 3547 207695_s_at -0.0941 0.0038
GSE26886 IGSF1 3547 223807_at 0.0156 0.9000
GSE29001 IGSF1 3547 207695_s_at 0.0298 0.8568
GSE38129 IGSF1 3547 207695_s_at -0.2289 0.0188
GSE45670 IGSF1 3547 207695_s_at -0.1649 0.1777
GSE53622 IGSF1 3547 164745 -0.3809 0.0000
GSE53624 IGSF1 3547 164745 -0.3873 0.0002
GSE63941 IGSF1 3547 207695_s_at 0.3090 0.2087
GSE77861 IGSF1 3547 207695_s_at -0.0385 0.7017
GSE97050 IGSF1 3547 A_33_P3371984 -0.1747 0.3924
SRP064894 IGSF1 3547 RNAseq -0.1514 0.6312
SRP133303 IGSF1 3547 RNAseq 1.2681 0.0098
SRP159526 IGSF1 3547 RNAseq -0.2917 0.6101
SRP219564 IGSF1 3547 RNAseq -0.4115 0.6255
TCGA IGSF1 3547 RNAseq -0.2972 0.2408

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by IGSF1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of IGSF1:

 

No record found for this gene.


 

Somatic mutations of IGSF1:

 

Generating mutation plots.

 

Highly correlated genes for IGSF1:

 

Showing top 20/192 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IGSF1FAM180B0.807695303
IGSF1CRHR10.693092403
IGSF1CLDN240.690097303
IGSF1BET1L0.685841303
IGSF1ZNF385D0.681651403
IGSF1ITSN10.680699303
IGSF1LRP2BP0.675069303
IGSF1KLHL410.672983403
IGSF1LINC012820.658344303
IGSF1NDNF0.657394303
IGSF1SEMA3D0.65667404
IGSF1OR2Z10.653789303
IGSF1HTR3A0.643067404
IGSF1CCDC780.642753303
IGSF1PAQR90.634143303
IGSF1OOSP20.628528404
IGSF1MMP240.628384303
IGSF1KRTAP20-10.62725303
IGSF1GREB1L0.612341303
IGSF1OR5AS10.610993303

For details and further investigation, click here