| Full name: fatty acid binding protein 3 | Alias Symbol: H-FABP|O-FABP | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 2170 | HGNC ID: HGNC:3557 | Ensembl Gene: ENSG00000121769 | OMIM ID: 134651 |
| Drug and gene relationship at DGIdb | |||
FABP3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of FABP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FABP3 | 2170 | 205738_s_at | -0.3815 | 0.4519 | |
| GSE20347 | FABP3 | 2170 | 205738_s_at | -0.0751 | 0.4280 | |
| GSE23400 | FABP3 | 2170 | 205738_s_at | -0.1934 | 0.0001 | |
| GSE26886 | FABP3 | 2170 | 205738_s_at | 0.2869 | 0.0227 | |
| GSE29001 | FABP3 | 2170 | 205738_s_at | -0.1580 | 0.3191 | |
| GSE38129 | FABP3 | 2170 | 205738_s_at | -0.5985 | 0.0400 | |
| GSE45670 | FABP3 | 2170 | 205738_s_at | -0.4004 | 0.0022 | |
| GSE53622 | FABP3 | 2170 | 91420 | -0.5061 | 0.0071 | |
| GSE53624 | FABP3 | 2170 | 91420 | -0.1874 | 0.1855 | |
| GSE63941 | FABP3 | 2170 | 205738_s_at | -1.2890 | 0.0003 | |
| GSE77861 | FABP3 | 2170 | 205738_s_at | 0.0515 | 0.8128 | |
| GSE97050 | FABP3 | 2170 | A_24_P62783 | -1.5627 | 0.1482 | |
| SRP007169 | FABP3 | 2170 | RNAseq | 3.5307 | 0.0025 | |
| SRP064894 | FABP3 | 2170 | RNAseq | 0.6361 | 0.1042 | |
| SRP133303 | FABP3 | 2170 | RNAseq | 0.1455 | 0.6931 | |
| SRP159526 | FABP3 | 2170 | RNAseq | -0.5182 | 0.2827 | |
| SRP219564 | FABP3 | 2170 | RNAseq | -1.3819 | 0.2083 | |
| TCGA | FABP3 | 2170 | RNAseq | -1.1788 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by FABP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FABP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FABP3 | 2170 | 0 | 6 | 24 | |
| GSE20123 | FABP3 | 2170 | 0 | 5 | 25 | |
| GSE43470 | FABP3 | 2170 | 4 | 6 | 33 | |
| GSE46452 | FABP3 | 2170 | 5 | 1 | 53 | |
| GSE47630 | FABP3 | 2170 | 8 | 3 | 29 | |
| GSE54993 | FABP3 | 2170 | 1 | 1 | 68 | |
| GSE54994 | FABP3 | 2170 | 10 | 3 | 40 | |
| GSE60625 | FABP3 | 2170 | 0 | 0 | 11 | |
| GSE74703 | FABP3 | 2170 | 3 | 4 | 29 | |
| GSE74704 | FABP3 | 2170 | 0 | 0 | 20 | |
| TCGA | FABP3 | 2170 | 12 | 18 | 66 |
Total number of gains: 43; Total number of losses: 47; Total Number of normals: 398.
Somatic mutations of FABP3:
Generating mutation plots.
Highly correlated genes for FABP3:
Showing top 20/623 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FABP3 | ABCA9 | 0.811193 | 3 | 0 | 3 |
| FABP3 | CORO6 | 0.78654 | 3 | 0 | 3 |
| FABP3 | GIPC3 | 0.752637 | 4 | 0 | 4 |
| FABP3 | TAF1 | 0.741779 | 3 | 0 | 3 |
| FABP3 | TMOD1 | 0.735579 | 7 | 0 | 7 |
| FABP3 | GABARAPL1 | 0.731563 | 5 | 0 | 5 |
| FABP3 | MYEF2 | 0.703095 | 3 | 0 | 3 |
| FABP3 | DDX42 | 0.702164 | 3 | 0 | 3 |
| FABP3 | ARHGEF25 | 0.690329 | 5 | 0 | 3 |
| FABP3 | CCDC136 | 0.686435 | 4 | 0 | 3 |
| FABP3 | APOB | 0.686107 | 4 | 0 | 4 |
| FABP3 | DACT3 | 0.685974 | 7 | 0 | 6 |
| FABP3 | MYOT | 0.680365 | 8 | 0 | 7 |
| FABP3 | CLIP3 | 0.680114 | 10 | 0 | 10 |
| FABP3 | PDE4DIP | 0.678984 | 8 | 0 | 7 |
| FABP3 | PLA2G5 | 0.677535 | 8 | 0 | 7 |
| FABP3 | CACNA1C | 0.675767 | 8 | 0 | 7 |
| FABP3 | GPR88 | 0.672988 | 5 | 0 | 3 |
| FABP3 | FXYD1 | 0.671113 | 8 | 0 | 8 |
| FABP3 | PYGM | 0.670511 | 9 | 0 | 8 |
For details and further investigation, click here
