| Full name: leucine rich repeat, Ig-like and transmembrane domains 1 | Alias Symbol: PAL|DKFZP434K091|FIGLER9 | ||
| Type: protein-coding gene | Cytoband: 10q23.1 | ||
| Entrez ID: 26103 | HGNC ID: HGNC:23404 | Ensembl Gene: ENSG00000148602 | OMIM ID: 616103 |
| Drug and gene relationship at DGIdb | |||
Expression of LRIT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRIT1 | 26103 | 211353_at | 0.0326 | 0.9121 | |
| GSE20347 | LRIT1 | 26103 | 211353_at | -0.0246 | 0.6849 | |
| GSE23400 | LRIT1 | 26103 | 211353_at | -0.0696 | 0.0517 | |
| GSE26886 | LRIT1 | 26103 | 211353_at | 0.0413 | 0.7153 | |
| GSE29001 | LRIT1 | 26103 | 211353_at | -0.0322 | 0.8565 | |
| GSE38129 | LRIT1 | 26103 | 211353_at | -0.0145 | 0.8107 | |
| GSE45670 | LRIT1 | 26103 | 211353_at | 0.0374 | 0.6931 | |
| GSE53622 | LRIT1 | 26103 | 106023 | 0.0802 | 0.4154 | |
| GSE53624 | LRIT1 | 26103 | 106023 | 0.0470 | 0.7309 | |
| GSE63941 | LRIT1 | 26103 | 211353_at | 0.1026 | 0.4026 | |
| GSE77861 | LRIT1 | 26103 | 211353_at | 0.0095 | 0.9252 | |
| GSE97050 | LRIT1 | 26103 | A_23_P115780 | -0.0654 | 0.7978 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRIT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRIT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRIT1 | 26103 | 1 | 6 | 23 | |
| GSE20123 | LRIT1 | 26103 | 1 | 5 | 24 | |
| GSE43470 | LRIT1 | 26103 | 1 | 6 | 36 | |
| GSE46452 | LRIT1 | 26103 | 0 | 11 | 48 | |
| GSE47630 | LRIT1 | 26103 | 2 | 14 | 24 | |
| GSE54993 | LRIT1 | 26103 | 7 | 0 | 63 | |
| GSE54994 | LRIT1 | 26103 | 1 | 12 | 40 | |
| GSE60625 | LRIT1 | 26103 | 0 | 0 | 11 | |
| GSE74703 | LRIT1 | 26103 | 1 | 4 | 31 | |
| GSE74704 | LRIT1 | 26103 | 0 | 3 | 17 | |
| TCGA | LRIT1 | 26103 | 9 | 25 | 62 |
Total number of gains: 23; Total number of losses: 86; Total Number of normals: 379.
Somatic mutations of LRIT1:
Generating mutation plots.
Highly correlated genes for LRIT1:
Showing top 20/656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRIT1 | OR2T27 | 0.875624 | 3 | 0 | 3 |
| LRIT1 | FOXA3 | 0.874979 | 3 | 0 | 3 |
| LRIT1 | SPACA3 | 0.854941 | 3 | 0 | 3 |
| LRIT1 | FBRSL1 | 0.854549 | 3 | 0 | 3 |
| LRIT1 | INSC | 0.830703 | 3 | 0 | 3 |
| LRIT1 | PAX6 | 0.828446 | 3 | 0 | 3 |
| LRIT1 | DCDC1 | 0.819416 | 3 | 0 | 3 |
| LRIT1 | MUC3A | 0.813606 | 3 | 0 | 3 |
| LRIT1 | RASL10B | 0.810313 | 3 | 0 | 3 |
| LRIT1 | TNNI2 | 0.808168 | 3 | 0 | 3 |
| LRIT1 | GJD4 | 0.807931 | 3 | 0 | 3 |
| LRIT1 | TNFAIP8L1 | 0.803739 | 3 | 0 | 3 |
| LRIT1 | TMEM229A | 0.799379 | 3 | 0 | 3 |
| LRIT1 | YY2 | 0.794225 | 3 | 0 | 3 |
| LRIT1 | PLA2G2C | 0.787433 | 3 | 0 | 3 |
| LRIT1 | RNF180 | 0.786985 | 3 | 0 | 3 |
| LRIT1 | BBC3 | 0.786702 | 3 | 0 | 3 |
| LRIT1 | GDF7 | 0.781107 | 3 | 0 | 3 |
| LRIT1 | BEST4 | 0.779176 | 3 | 0 | 3 |
| LRIT1 | C1QL2 | 0.771426 | 3 | 0 | 3 |
For details and further investigation, click here
