| Full name: phospholipase A2 group XIIB | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 84647 | HGNC ID: HGNC:18555 | Ensembl Gene: ENSG00000138308 | OMIM ID: 611653 |
| Drug and gene relationship at DGIdb | |||
PLA2G12B involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway | |
| hsa04270 | Vascular smooth muscle contraction |
Expression of PLA2G12B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLA2G12B | 84647 | 224411_at | -0.1319 | 0.4740 | |
| GSE26886 | PLA2G12B | 84647 | 224411_at | -0.0378 | 0.7480 | |
| GSE45670 | PLA2G12B | 84647 | 224411_at | -0.0128 | 0.8962 | |
| GSE53622 | PLA2G12B | 84647 | 6201 | 0.1545 | 0.0636 | |
| GSE53624 | PLA2G12B | 84647 | 6201 | 0.1016 | 0.2968 | |
| GSE63941 | PLA2G12B | 84647 | 224411_at | 0.2016 | 0.1161 | |
| GSE77861 | PLA2G12B | 84647 | 224411_at | -0.0038 | 0.9647 | |
| GSE97050 | PLA2G12B | 84647 | A_23_P388150 | -0.1348 | 0.5246 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PLA2G12B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLA2G12B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLA2G12B | 84647 | 3 | 4 | 23 | |
| GSE20123 | PLA2G12B | 84647 | 3 | 3 | 24 | |
| GSE43470 | PLA2G12B | 84647 | 1 | 8 | 34 | |
| GSE46452 | PLA2G12B | 84647 | 0 | 11 | 48 | |
| GSE47630 | PLA2G12B | 84647 | 2 | 14 | 24 | |
| GSE54993 | PLA2G12B | 84647 | 7 | 0 | 63 | |
| GSE54994 | PLA2G12B | 84647 | 2 | 11 | 40 | |
| GSE60625 | PLA2G12B | 84647 | 0 | 0 | 11 | |
| GSE74703 | PLA2G12B | 84647 | 1 | 5 | 30 | |
| GSE74704 | PLA2G12B | 84647 | 1 | 1 | 18 | |
| TCGA | PLA2G12B | 84647 | 11 | 23 | 62 |
Total number of gains: 31; Total number of losses: 80; Total Number of normals: 377.
Somatic mutations of PLA2G12B:
Generating mutation plots.
Highly correlated genes for PLA2G12B:
Showing top 20/437 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLA2G12B | OR2T1 | 0.80957 | 3 | 0 | 3 |
| PLA2G12B | CECR9 | 0.79678 | 3 | 0 | 3 |
| PLA2G12B | DCDC1 | 0.786992 | 3 | 0 | 3 |
| PLA2G12B | OR2T27 | 0.77515 | 3 | 0 | 3 |
| PLA2G12B | ACTL6B | 0.774029 | 4 | 0 | 4 |
| PLA2G12B | CPLX2 | 0.770884 | 5 | 0 | 5 |
| PLA2G12B | BBC3 | 0.761741 | 3 | 0 | 3 |
| PLA2G12B | KCNH3 | 0.761733 | 4 | 0 | 4 |
| PLA2G12B | GRXCR2 | 0.755278 | 3 | 0 | 3 |
| PLA2G12B | PRSS38 | 0.755199 | 3 | 0 | 3 |
| PLA2G12B | FAM71F1 | 0.754286 | 4 | 0 | 4 |
| PLA2G12B | GPR182 | 0.753662 | 5 | 0 | 5 |
| PLA2G12B | OR2A5 | 0.753244 | 3 | 0 | 3 |
| PLA2G12B | ABTB1 | 0.75203 | 3 | 0 | 3 |
| PLA2G12B | ANO7 | 0.745231 | 4 | 0 | 4 |
| PLA2G12B | CHST10 | 0.745061 | 3 | 0 | 3 |
| PLA2G12B | FAM131A | 0.744798 | 3 | 0 | 3 |
| PLA2G12B | PLA2G2C | 0.744076 | 3 | 0 | 3 |
| PLA2G12B | YY2 | 0.740191 | 3 | 0 | 3 |
| PLA2G12B | KCNC3 | 0.736732 | 3 | 0 | 3 |
For details and further investigation, click here
