| Full name: DEAH-box helicase 40 | Alias Symbol: ARG147|PAD|FLJ22060 | ||
| Type: protein-coding gene | Cytoband: 17q23.1 | ||
| Entrez ID: 79665 | HGNC ID: HGNC:18018 | Ensembl Gene: ENSG00000108406 | OMIM ID: 607570 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX40 | 79665 | 218277_s_at | 0.0562 | 0.8749 | |
| GSE20347 | DHX40 | 79665 | 218277_s_at | -0.0410 | 0.8498 | |
| GSE23400 | DHX40 | 79665 | 218277_s_at | 0.3947 | 0.0000 | |
| GSE26886 | DHX40 | 79665 | 218277_s_at | 0.8808 | 0.0001 | |
| GSE29001 | DHX40 | 79665 | 218277_s_at | -0.0692 | 0.8436 | |
| GSE38129 | DHX40 | 79665 | 218277_s_at | 0.0707 | 0.6325 | |
| GSE45670 | DHX40 | 79665 | 218277_s_at | -0.3618 | 0.0286 | |
| GSE63941 | DHX40 | 79665 | 222574_s_at | 0.4937 | 0.6794 | |
| GSE77861 | DHX40 | 79665 | 218277_s_at | 0.5243 | 0.0715 | |
| GSE97050 | DHX40 | 79665 | A_33_P3424112 | 0.0615 | 0.8269 | |
| SRP007169 | DHX40 | 79665 | RNAseq | 0.3209 | 0.5090 | |
| SRP008496 | DHX40 | 79665 | RNAseq | 0.3724 | 0.1871 | |
| SRP064894 | DHX40 | 79665 | RNAseq | 0.0498 | 0.8201 | |
| SRP133303 | DHX40 | 79665 | RNAseq | 0.3427 | 0.0710 | |
| SRP159526 | DHX40 | 79665 | RNAseq | 0.4079 | 0.0656 | |
| SRP193095 | DHX40 | 79665 | RNAseq | -0.0581 | 0.4865 | |
| SRP219564 | DHX40 | 79665 | RNAseq | -0.2866 | 0.2039 | |
| TCGA | DHX40 | 79665 | RNAseq | -0.0058 | 0.9077 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DHX40 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DHX40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX40 | 79665 | 6 | 1 | 23 | |
| GSE20123 | DHX40 | 79665 | 6 | 1 | 23 | |
| GSE43470 | DHX40 | 79665 | 4 | 0 | 39 | |
| GSE46452 | DHX40 | 79665 | 32 | 0 | 27 | |
| GSE47630 | DHX40 | 79665 | 7 | 1 | 32 | |
| GSE54993 | DHX40 | 79665 | 2 | 5 | 63 | |
| GSE54994 | DHX40 | 79665 | 9 | 5 | 39 | |
| GSE60625 | DHX40 | 79665 | 4 | 0 | 7 | |
| GSE74703 | DHX40 | 79665 | 4 | 0 | 32 | |
| GSE74704 | DHX40 | 79665 | 5 | 1 | 14 | |
| TCGA | DHX40 | 79665 | 26 | 8 | 62 |
Total number of gains: 105; Total number of losses: 22; Total Number of normals: 361.
Somatic mutations of DHX40:
Generating mutation plots.
Highly correlated genes for DHX40:
Showing top 20/725 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX40 | BOD1 | 0.852299 | 3 | 0 | 3 |
| DHX40 | MCPH1 | 0.843733 | 3 | 0 | 3 |
| DHX40 | SPRED1 | 0.826454 | 3 | 0 | 3 |
| DHX40 | LMBRD2 | 0.809923 | 3 | 0 | 3 |
| DHX40 | RICTOR | 0.789205 | 3 | 0 | 3 |
| DHX40 | EXOSC8 | 0.782651 | 3 | 0 | 3 |
| DHX40 | ECSIT | 0.779347 | 3 | 0 | 3 |
| DHX40 | RPS19BP1 | 0.779073 | 3 | 0 | 3 |
| DHX40 | TMEM205 | 0.778999 | 3 | 0 | 3 |
| DHX40 | LSM10 | 0.777771 | 3 | 0 | 3 |
| DHX40 | U2SURP | 0.77528 | 4 | 0 | 4 |
| DHX40 | ZNF689 | 0.769801 | 3 | 0 | 3 |
| DHX40 | TMTC3 | 0.766579 | 3 | 0 | 3 |
| DHX40 | STARD3NL | 0.764712 | 3 | 0 | 3 |
| DHX40 | SLC38A6 | 0.76434 | 3 | 0 | 3 |
| DHX40 | UBR1 | 0.763749 | 3 | 0 | 3 |
| DHX40 | RBM18 | 0.762935 | 3 | 0 | 3 |
| DHX40 | CEP97 | 0.762725 | 3 | 0 | 3 |
| DHX40 | ZNF764 | 0.762536 | 3 | 0 | 3 |
| DHX40 | GOLIM4 | 0.762507 | 3 | 0 | 3 |
For details and further investigation, click here
