| Full name: family with sequence similarity 120B | Alias Symbol: PGCC1|CCPG|SAN1 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 84498 | HGNC ID: HGNC:21109 | Ensembl Gene: ENSG00000112584 | OMIM ID: 612266 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM120B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM120B | 84498 | 227895_at | 0.0367 | 0.9262 | |
| GSE26886 | FAM120B | 84498 | 227895_at | -0.3945 | 0.0264 | |
| GSE45670 | FAM120B | 84498 | 227895_at | 0.0510 | 0.6415 | |
| GSE53622 | FAM120B | 84498 | 55806 | -0.4185 | 0.0000 | |
| GSE53624 | FAM120B | 84498 | 55806 | -0.2384 | 0.0001 | |
| GSE63941 | FAM120B | 84498 | 226774_at | -0.5290 | 0.1641 | |
| GSE77861 | FAM120B | 84498 | 226774_at | 0.4646 | 0.1406 | |
| GSE97050 | FAM120B | 84498 | A_23_P313476 | -0.4966 | 0.1200 | |
| SRP007169 | FAM120B | 84498 | RNAseq | 0.4168 | 0.2149 | |
| SRP008496 | FAM120B | 84498 | RNAseq | 0.4495 | 0.0426 | |
| SRP064894 | FAM120B | 84498 | RNAseq | -0.0645 | 0.5782 | |
| SRP133303 | FAM120B | 84498 | RNAseq | -0.1064 | 0.3482 | |
| SRP159526 | FAM120B | 84498 | RNAseq | -0.1884 | 0.3543 | |
| SRP193095 | FAM120B | 84498 | RNAseq | -0.0275 | 0.8074 | |
| SRP219564 | FAM120B | 84498 | RNAseq | -0.0129 | 0.9580 | |
| TCGA | FAM120B | 84498 | RNAseq | -0.1188 | 0.0167 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM120B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM120B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM120B | 84498 | 4 | 6 | 20 | |
| GSE20123 | FAM120B | 84498 | 4 | 6 | 20 | |
| GSE43470 | FAM120B | 84498 | 2 | 0 | 41 | |
| GSE46452 | FAM120B | 84498 | 3 | 10 | 46 | |
| GSE47630 | FAM120B | 84498 | 7 | 7 | 26 | |
| GSE54993 | FAM120B | 84498 | 4 | 3 | 63 | |
| GSE54994 | FAM120B | 84498 | 10 | 8 | 35 | |
| GSE60625 | FAM120B | 84498 | 1 | 1 | 9 | |
| GSE74703 | FAM120B | 84498 | 2 | 0 | 34 | |
| GSE74704 | FAM120B | 84498 | 2 | 3 | 15 | |
| TCGA | FAM120B | 84498 | 14 | 20 | 62 |
Total number of gains: 53; Total number of losses: 64; Total Number of normals: 371.
Somatic mutations of FAM120B:
Generating mutation plots.
Highly correlated genes for FAM120B:
Showing top 20/204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM120B | EIF4ENIF1 | 0.817061 | 3 | 0 | 3 |
| FAM120B | TTC17 | 0.816388 | 3 | 0 | 3 |
| FAM120B | PTAR1 | 0.799841 | 3 | 0 | 3 |
| FAM120B | ASNSD1 | 0.784871 | 3 | 0 | 3 |
| FAM120B | ZSCAN29 | 0.764196 | 3 | 0 | 3 |
| FAM120B | M6PR | 0.74776 | 3 | 0 | 3 |
| FAM120B | IQCE | 0.742979 | 3 | 0 | 3 |
| FAM120B | CDK5RAP3 | 0.741375 | 3 | 0 | 3 |
| FAM120B | SLMAP | 0.741283 | 3 | 0 | 3 |
| FAM120B | NDUFS2 | 0.739764 | 3 | 0 | 3 |
| FAM120B | ETV6 | 0.735648 | 3 | 0 | 3 |
| FAM120B | ZNF260 | 0.735641 | 3 | 0 | 3 |
| FAM120B | JMJD1C | 0.730967 | 3 | 0 | 3 |
| FAM120B | MEF2D | 0.727832 | 3 | 0 | 3 |
| FAM120B | LUC7L3 | 0.723823 | 3 | 0 | 3 |
| FAM120B | GCLC | 0.720188 | 3 | 0 | 3 |
| FAM120B | UPF1 | 0.717642 | 3 | 0 | 3 |
| FAM120B | PPP1R12A | 0.717052 | 3 | 0 | 3 |
| FAM120B | LARP4 | 0.715028 | 5 | 0 | 4 |
| FAM120B | ZFAND3 | 0.714475 | 3 | 0 | 3 |
For details and further investigation, click here
