| Full name: family with sequence similarity 193 member B | Alias Symbol: KIAA1931|FLJ10404|IRIZIO | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 54540 | HGNC ID: HGNC:25524 | Ensembl Gene: ENSG00000146067 | OMIM ID: 615813 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM193B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM193B | 54540 | 218920_at | -0.0532 | 0.9305 | |
| GSE20347 | FAM193B | 54540 | 218920_at | -0.4033 | 0.0028 | |
| GSE23400 | FAM193B | 54540 | 218920_at | -0.1763 | 0.0017 | |
| GSE26886 | FAM193B | 54540 | 218920_at | -0.3474 | 0.0796 | |
| GSE29001 | FAM193B | 54540 | 218920_at | -0.2557 | 0.2448 | |
| GSE38129 | FAM193B | 54540 | 218920_at | -0.3591 | 0.0069 | |
| GSE45670 | FAM193B | 54540 | 218920_at | -0.1106 | 0.6344 | |
| GSE53622 | FAM193B | 54540 | 626 | -0.1140 | 0.2893 | |
| GSE53624 | FAM193B | 54540 | 626 | -0.2271 | 0.0030 | |
| GSE63941 | FAM193B | 54540 | 218920_at | 0.4291 | 0.1399 | |
| GSE77861 | FAM193B | 54540 | 218920_at | -0.0845 | 0.7524 | |
| GSE97050 | FAM193B | 54540 | A_23_P213863 | -0.1501 | 0.6645 | |
| SRP007169 | FAM193B | 54540 | RNAseq | -1.4862 | 0.0004 | |
| SRP008496 | FAM193B | 54540 | RNAseq | -1.7021 | 0.0000 | |
| SRP064894 | FAM193B | 54540 | RNAseq | 0.1248 | 0.4387 | |
| SRP133303 | FAM193B | 54540 | RNAseq | -0.3989 | 0.0173 | |
| SRP159526 | FAM193B | 54540 | RNAseq | -0.2861 | 0.3897 | |
| SRP193095 | FAM193B | 54540 | RNAseq | 0.0517 | 0.7412 | |
| SRP219564 | FAM193B | 54540 | RNAseq | 0.2157 | 0.6312 | |
| TCGA | FAM193B | 54540 | RNAseq | -0.0814 | 0.2047 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FAM193B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM193B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM193B | 54540 | 2 | 13 | 15 | |
| GSE20123 | FAM193B | 54540 | 2 | 13 | 15 | |
| GSE43470 | FAM193B | 54540 | 1 | 11 | 31 | |
| GSE46452 | FAM193B | 54540 | 0 | 27 | 32 | |
| GSE47630 | FAM193B | 54540 | 1 | 20 | 19 | |
| GSE54993 | FAM193B | 54540 | 10 | 2 | 58 | |
| GSE54994 | FAM193B | 54540 | 2 | 17 | 34 | |
| GSE60625 | FAM193B | 54540 | 1 | 0 | 10 | |
| GSE74703 | FAM193B | 54540 | 1 | 7 | 28 | |
| GSE74704 | FAM193B | 54540 | 1 | 6 | 13 | |
| TCGA | FAM193B | 54540 | 8 | 34 | 54 |
Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.
Somatic mutations of FAM193B:
Generating mutation plots.
Highly correlated genes for FAM193B:
Showing top 20/361 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM193B | LUC7L3 | 0.783442 | 3 | 0 | 3 |
| FAM193B | INPP5E | 0.767781 | 3 | 0 | 3 |
| FAM193B | CPLX1 | 0.727948 | 3 | 0 | 3 |
| FAM193B | PTPN23 | 0.725089 | 3 | 0 | 3 |
| FAM193B | DEPDC5 | 0.723622 | 3 | 0 | 3 |
| FAM193B | DPP7 | 0.723024 | 3 | 0 | 3 |
| FAM193B | AKAP17A | 0.709915 | 5 | 0 | 5 |
| FAM193B | CECR7 | 0.709381 | 3 | 0 | 3 |
| FAM193B | DVL1 | 0.705879 | 4 | 0 | 3 |
| FAM193B | ANKRD18A | 0.697361 | 3 | 0 | 3 |
| FAM193B | SHB | 0.693782 | 3 | 0 | 3 |
| FAM193B | ZFYVE16 | 0.692416 | 3 | 0 | 3 |
| FAM193B | UPF3A | 0.690445 | 4 | 0 | 3 |
| FAM193B | TMEM214 | 0.688119 | 4 | 0 | 4 |
| FAM193B | UBR4 | 0.68654 | 4 | 0 | 4 |
| FAM193B | ZNF787 | 0.686188 | 3 | 0 | 3 |
| FAM193B | CAPNS1 | 0.685432 | 3 | 0 | 3 |
| FAM193B | AK1 | 0.684027 | 3 | 0 | 3 |
| FAM193B | ZFP36L2 | 0.682763 | 5 | 0 | 5 |
| FAM193B | INO80E | 0.681259 | 3 | 0 | 3 |
For details and further investigation, click here
