| Full name: inositol polyphosphate-4-phosphatase type I A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 3631 | HGNC ID: HGNC:6074 | Ensembl Gene: ENSG00000040933 | OMIM ID: 600916 |
| Drug and gene relationship at DGIdb | |||
Expression of INPP4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INPP4A | 3631 | 227087_at | 0.1208 | 0.8646 | |
| GSE20347 | INPP4A | 3631 | 204553_x_at | 0.1989 | 0.0186 | |
| GSE23400 | INPP4A | 3631 | 204553_x_at | -0.0100 | 0.7958 | |
| GSE26886 | INPP4A | 3631 | 227087_at | 1.2945 | 0.0001 | |
| GSE29001 | INPP4A | 3631 | 204552_at | 0.2316 | 0.2256 | |
| GSE38129 | INPP4A | 3631 | 204553_x_at | 0.2040 | 0.0106 | |
| GSE45670 | INPP4A | 3631 | 227087_at | -0.2257 | 0.3991 | |
| GSE53622 | INPP4A | 3631 | 8445 | 0.2782 | 0.0072 | |
| GSE53624 | INPP4A | 3631 | 8445 | 0.7833 | 0.0000 | |
| GSE63941 | INPP4A | 3631 | 227087_at | -0.2400 | 0.6029 | |
| GSE77861 | INPP4A | 3631 | 227087_at | 0.9845 | 0.0360 | |
| GSE97050 | INPP4A | 3631 | A_23_P393531 | -0.0784 | 0.7814 | |
| SRP007169 | INPP4A | 3631 | RNAseq | 0.8403 | 0.0206 | |
| SRP008496 | INPP4A | 3631 | RNAseq | 0.9825 | 0.0000 | |
| SRP064894 | INPP4A | 3631 | RNAseq | 0.4388 | 0.0419 | |
| SRP133303 | INPP4A | 3631 | RNAseq | 0.3145 | 0.0369 | |
| SRP159526 | INPP4A | 3631 | RNAseq | 1.0287 | 0.0019 | |
| SRP193095 | INPP4A | 3631 | RNAseq | 0.6925 | 0.0000 | |
| SRP219564 | INPP4A | 3631 | RNAseq | -0.0923 | 0.8753 | |
| TCGA | INPP4A | 3631 | RNAseq | 0.0109 | 0.8757 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by INPP4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INPP4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INPP4A | 3631 | 6 | 2 | 22 | |
| GSE20123 | INPP4A | 3631 | 6 | 2 | 22 | |
| GSE43470 | INPP4A | 3631 | 3 | 2 | 38 | |
| GSE46452 | INPP4A | 3631 | 2 | 3 | 54 | |
| GSE47630 | INPP4A | 3631 | 7 | 0 | 33 | |
| GSE54993 | INPP4A | 3631 | 0 | 6 | 64 | |
| GSE54994 | INPP4A | 3631 | 10 | 0 | 43 | |
| GSE60625 | INPP4A | 3631 | 0 | 3 | 8 | |
| GSE74703 | INPP4A | 3631 | 3 | 2 | 31 | |
| GSE74704 | INPP4A | 3631 | 4 | 1 | 15 | |
| TCGA | INPP4A | 3631 | 34 | 5 | 57 |
Total number of gains: 75; Total number of losses: 26; Total Number of normals: 387.
Somatic mutations of INPP4A:
Generating mutation plots.
Highly correlated genes for INPP4A:
Showing top 20/1106 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INPP4A | RPGR | 0.786644 | 3 | 0 | 3 |
| INPP4A | THAP5 | 0.7794 | 3 | 0 | 3 |
| INPP4A | CTBP2 | 0.748856 | 3 | 0 | 3 |
| INPP4A | ECSIT | 0.743138 | 3 | 0 | 3 |
| INPP4A | SORL1 | 0.73602 | 3 | 0 | 3 |
| INPP4A | BRD9 | 0.732959 | 3 | 0 | 3 |
| INPP4A | POPDC2 | 0.728581 | 3 | 0 | 3 |
| INPP4A | SPPL2A | 0.727045 | 3 | 0 | 3 |
| INPP4A | WDR81 | 0.726765 | 4 | 0 | 3 |
| INPP4A | PTPN4 | 0.726236 | 4 | 0 | 3 |
| INPP4A | LUC7L3 | 0.725746 | 3 | 0 | 3 |
| INPP4A | MEF2A | 0.724767 | 4 | 0 | 4 |
| INPP4A | FGF12 | 0.720808 | 3 | 0 | 3 |
| INPP4A | C1orf115 | 0.719304 | 4 | 0 | 4 |
| INPP4A | EMILIN2 | 0.719263 | 5 | 0 | 5 |
| INPP4A | FANCL | 0.717689 | 4 | 0 | 3 |
| INPP4A | THOC1 | 0.714757 | 4 | 0 | 4 |
| INPP4A | SRRT | 0.714547 | 3 | 0 | 3 |
| INPP4A | PIGX | 0.712991 | 3 | 0 | 3 |
| INPP4A | ZNF280C | 0.711538 | 3 | 0 | 3 |
For details and further investigation, click here
