| Full name: MLLT6, PHD finger containing | Alias Symbol: AF17|FLJ23480 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 4302 | HGNC ID: HGNC:7138 | Ensembl Gene: ENSG00000275023 | OMIM ID: 600328 |
| Drug and gene relationship at DGIdb | |||
Expression of MLLT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MLLT6 | 4302 | 224784_at | 0.1537 | 0.7449 | |
| GSE26886 | MLLT6 | 4302 | 224784_at | -0.5003 | 0.0316 | |
| GSE45670 | MLLT6 | 4302 | 224784_at | -0.4179 | 0.0775 | |
| GSE53622 | MLLT6 | 4302 | 62516 | -0.4285 | 0.0000 | |
| GSE53624 | MLLT6 | 4302 | 62516 | -0.5897 | 0.0000 | |
| GSE63941 | MLLT6 | 4302 | 224784_at | 0.9648 | 0.0796 | |
| GSE77861 | MLLT6 | 4302 | 224784_at | 0.0669 | 0.8510 | |
| GSE97050 | MLLT6 | 4302 | A_33_P3376622 | -0.4106 | 0.1927 | |
| SRP007169 | MLLT6 | 4302 | RNAseq | 0.8437 | 0.0353 | |
| SRP008496 | MLLT6 | 4302 | RNAseq | 0.7066 | 0.0045 | |
| SRP064894 | MLLT6 | 4302 | RNAseq | -0.0486 | 0.7576 | |
| SRP133303 | MLLT6 | 4302 | RNAseq | -0.6664 | 0.0001 | |
| SRP159526 | MLLT6 | 4302 | RNAseq | -0.5512 | 0.0622 | |
| SRP193095 | MLLT6 | 4302 | RNAseq | 0.0449 | 0.7096 | |
| SRP219564 | MLLT6 | 4302 | RNAseq | -0.4313 | 0.2283 | |
| TCGA | MLLT6 | 4302 | RNAseq | -0.2217 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MLLT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MLLT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MLLT6 | 4302 | 7 | 1 | 22 | |
| GSE20123 | MLLT6 | 4302 | 7 | 1 | 22 | |
| GSE43470 | MLLT6 | 4302 | 0 | 1 | 42 | |
| GSE46452 | MLLT6 | 4302 | 34 | 0 | 25 | |
| GSE47630 | MLLT6 | 4302 | 8 | 1 | 31 | |
| GSE54993 | MLLT6 | 4302 | 3 | 4 | 63 | |
| GSE54994 | MLLT6 | 4302 | 8 | 5 | 40 | |
| GSE60625 | MLLT6 | 4302 | 4 | 0 | 7 | |
| GSE74703 | MLLT6 | 4302 | 0 | 0 | 36 | |
| GSE74704 | MLLT6 | 4302 | 4 | 1 | 15 | |
| TCGA | MLLT6 | 4302 | 19 | 9 | 68 |
Total number of gains: 94; Total number of losses: 23; Total Number of normals: 371.
Somatic mutations of MLLT6:
Generating mutation plots.
Highly correlated genes for MLLT6:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MLLT6 | ZNF397 | 0.801061 | 3 | 0 | 3 |
| MLLT6 | ZNF76 | 0.795599 | 3 | 0 | 3 |
| MLLT6 | MIA3 | 0.793336 | 4 | 0 | 4 |
| MLLT6 | LUC7L3 | 0.787536 | 3 | 0 | 3 |
| MLLT6 | PIP4K2B | 0.772635 | 3 | 0 | 3 |
| MLLT6 | KCTD15 | 0.768761 | 3 | 0 | 3 |
| MLLT6 | EHMT2 | 0.762201 | 3 | 0 | 3 |
| MLLT6 | KIAA0513 | 0.752034 | 3 | 0 | 3 |
| MLLT6 | POLDIP3 | 0.738876 | 3 | 0 | 3 |
| MLLT6 | AKAP17A | 0.738021 | 3 | 0 | 3 |
| MLLT6 | CDK10 | 0.727849 | 4 | 0 | 4 |
| MLLT6 | ZNF791 | 0.723476 | 3 | 0 | 3 |
| MLLT6 | ANAPC16 | 0.717689 | 3 | 0 | 3 |
| MLLT6 | ZFYVE27 | 0.717285 | 3 | 0 | 3 |
| MLLT6 | DMAP1 | 0.715961 | 3 | 0 | 3 |
| MLLT6 | DHX30 | 0.713613 | 3 | 0 | 3 |
| MLLT6 | FHL5 | 0.706921 | 3 | 0 | 3 |
| MLLT6 | CDK5RAP3 | 0.705422 | 4 | 0 | 4 |
| MLLT6 | FAM149B1 | 0.705171 | 3 | 0 | 3 |
| MLLT6 | WDR37 | 0.703696 | 3 | 0 | 3 |
For details and further investigation, click here
