| Full name: latexin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q25.32 | ||
| Entrez ID: 56925 | HGNC ID: HGNC:13347 | Ensembl Gene: ENSG00000079257 | OMIM ID: 609305 |
| Drug and gene relationship at DGIdb | |||
Expression of LXN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LXN | 56925 | 218729_at | -0.9218 | 0.4406 | |
| GSE20347 | LXN | 56925 | 218729_at | -0.2826 | 0.3434 | |
| GSE23400 | LXN | 56925 | 218729_at | 0.3740 | 0.0017 | |
| GSE26886 | LXN | 56925 | 218729_at | -0.2920 | 0.5395 | |
| GSE29001 | LXN | 56925 | 218729_at | -0.4621 | 0.5268 | |
| GSE38129 | LXN | 56925 | 218729_at | -0.0011 | 0.9974 | |
| GSE45670 | LXN | 56925 | 218729_at | -1.0732 | 0.0031 | |
| GSE53622 | LXN | 56925 | 60222 | 0.1630 | 0.2841 | |
| GSE53624 | LXN | 56925 | 60222 | -0.1663 | 0.2165 | |
| GSE63941 | LXN | 56925 | 218729_at | -6.7231 | 0.0000 | |
| GSE77861 | LXN | 56925 | 218729_at | -0.5115 | 0.3457 | |
| GSE97050 | LXN | 56925 | A_33_P3234697 | 0.8018 | 0.1939 | |
| SRP007169 | LXN | 56925 | RNAseq | 0.4060 | 0.4417 | |
| SRP064894 | LXN | 56925 | RNAseq | 0.8445 | 0.0125 | |
| SRP133303 | LXN | 56925 | RNAseq | 0.4207 | 0.0146 | |
| SRP159526 | LXN | 56925 | RNAseq | 0.6202 | 0.2924 | |
| SRP193095 | LXN | 56925 | RNAseq | -0.2421 | 0.2090 | |
| SRP219564 | LXN | 56925 | RNAseq | 0.7326 | 0.2640 | |
| TCGA | LXN | 56925 | RNAseq | 0.0499 | 0.7602 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LXN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LXN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LXN | 56925 | 22 | 0 | 8 | |
| GSE20123 | LXN | 56925 | 22 | 0 | 8 | |
| GSE43470 | LXN | 56925 | 23 | 0 | 20 | |
| GSE46452 | LXN | 56925 | 18 | 2 | 39 | |
| GSE47630 | LXN | 56925 | 18 | 4 | 18 | |
| GSE54993 | LXN | 56925 | 1 | 11 | 58 | |
| GSE54994 | LXN | 56925 | 38 | 1 | 14 | |
| GSE60625 | LXN | 56925 | 0 | 6 | 5 | |
| GSE74703 | LXN | 56925 | 20 | 0 | 16 | |
| GSE74704 | LXN | 56925 | 14 | 0 | 6 | |
| TCGA | LXN | 56925 | 75 | 1 | 20 |
Total number of gains: 251; Total number of losses: 25; Total Number of normals: 212.
Somatic mutations of LXN:
Generating mutation plots.
Highly correlated genes for LXN:
Showing top 20/555 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LXN | ANKRD44 | 0.710894 | 5 | 0 | 4 |
| LXN | STEAP4 | 0.704146 | 3 | 0 | 3 |
| LXN | FAM160B1 | 0.703658 | 3 | 0 | 3 |
| LXN | SMPD1 | 0.696885 | 6 | 0 | 5 |
| LXN | SH3BP5 | 0.693865 | 4 | 0 | 3 |
| LXN | MSI2 | 0.691233 | 3 | 0 | 3 |
| LXN | FBXL7 | 0.686816 | 4 | 0 | 3 |
| LXN | CYP4V2 | 0.685271 | 4 | 0 | 4 |
| LXN | MAGI2-AS3 | 0.684085 | 4 | 0 | 4 |
| LXN | LINC01279 | 0.683168 | 3 | 0 | 3 |
| LXN | CCDC3 | 0.681191 | 3 | 0 | 3 |
| LXN | TNFRSF19 | 0.681115 | 4 | 0 | 3 |
| LXN | CNOT4 | 0.681067 | 3 | 0 | 3 |
| LXN | NDUFS1 | 0.678685 | 3 | 0 | 3 |
| LXN | ZNF521 | 0.676383 | 5 | 0 | 4 |
| LXN | PEG3 | 0.675199 | 4 | 0 | 4 |
| LXN | APOOL | 0.674788 | 3 | 0 | 3 |
| LXN | ZNF382 | 0.672233 | 3 | 0 | 3 |
| LXN | FIBIN | 0.672031 | 5 | 0 | 5 |
| LXN | EIF3L | 0.665627 | 4 | 0 | 4 |
For details and further investigation, click here
