| Full name: coiled-coil domain containing 3 | Alias Symbol: DKFZp761F241 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 83643 | HGNC ID: HGNC:23813 | Ensembl Gene: ENSG00000151468 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC3 | 83643 | 223316_at | -0.8705 | 0.2740 | |
| GSE26886 | CCDC3 | 83643 | 223316_at | -0.8827 | 0.0017 | |
| GSE45670 | CCDC3 | 83643 | 223316_at | -1.5947 | 0.0000 | |
| GSE53622 | CCDC3 | 83643 | 49415 | -1.2074 | 0.0000 | |
| GSE53624 | CCDC3 | 83643 | 49415 | -1.1090 | 0.0000 | |
| GSE63941 | CCDC3 | 83643 | 223316_at | -0.9108 | 0.1658 | |
| GSE77861 | CCDC3 | 83643 | 223316_at | -0.0237 | 0.9534 | |
| GSE97050 | CCDC3 | 83643 | A_24_P369232 | -0.3834 | 0.2609 | |
| SRP007169 | CCDC3 | 83643 | RNAseq | 3.0861 | 0.0001 | |
| SRP008496 | CCDC3 | 83643 | RNAseq | 2.8312 | 0.0000 | |
| SRP064894 | CCDC3 | 83643 | RNAseq | -0.9108 | 0.0220 | |
| SRP133303 | CCDC3 | 83643 | RNAseq | -1.5054 | 0.0000 | |
| SRP159526 | CCDC3 | 83643 | RNAseq | -1.2587 | 0.0148 | |
| SRP193095 | CCDC3 | 83643 | RNAseq | 0.3833 | 0.1394 | |
| SRP219564 | CCDC3 | 83643 | RNAseq | -1.7065 | 0.0128 | |
| TCGA | CCDC3 | 83643 | RNAseq | -0.2333 | 0.0483 |
Upregulated datasets: 2; Downregulated datasets: 6.
Survival by CCDC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC3 | 83643 | 6 | 7 | 17 | |
| GSE20123 | CCDC3 | 83643 | 6 | 6 | 18 | |
| GSE43470 | CCDC3 | 83643 | 3 | 5 | 35 | |
| GSE46452 | CCDC3 | 83643 | 2 | 14 | 43 | |
| GSE47630 | CCDC3 | 83643 | 6 | 14 | 20 | |
| GSE54993 | CCDC3 | 83643 | 11 | 1 | 58 | |
| GSE54994 | CCDC3 | 83643 | 4 | 9 | 40 | |
| GSE60625 | CCDC3 | 83643 | 0 | 0 | 11 | |
| GSE74703 | CCDC3 | 83643 | 2 | 3 | 31 | |
| GSE74704 | CCDC3 | 83643 | 1 | 5 | 14 | |
| TCGA | CCDC3 | 83643 | 21 | 24 | 51 |
Total number of gains: 62; Total number of losses: 88; Total Number of normals: 338.
Somatic mutations of CCDC3:
Generating mutation plots.
Highly correlated genes for CCDC3:
Showing top 20/832 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC3 | FBLN1 | 0.787175 | 5 | 0 | 5 |
| CCDC3 | RNASE4 | 0.779077 | 3 | 0 | 3 |
| CCDC3 | CLEC3B | 0.769263 | 3 | 0 | 3 |
| CCDC3 | EBF1 | 0.765757 | 5 | 0 | 5 |
| CCDC3 | FHL5 | 0.763241 | 5 | 0 | 5 |
| CCDC3 | MRVI1 | 0.75047 | 6 | 0 | 6 |
| CCDC3 | CYP21A2 | 0.747203 | 3 | 0 | 3 |
| CCDC3 | PCP4 | 0.741093 | 5 | 0 | 5 |
| CCDC3 | SPON1 | 0.740858 | 4 | 0 | 4 |
| CCDC3 | RERGL | 0.73933 | 5 | 0 | 5 |
| CCDC3 | GFRA1 | 0.736929 | 5 | 0 | 5 |
| CCDC3 | SEC31B | 0.734269 | 3 | 0 | 3 |
| CCDC3 | ERLEC1 | 0.734261 | 3 | 0 | 3 |
| CCDC3 | SLITRK3 | 0.733905 | 5 | 0 | 5 |
| CCDC3 | TLE2 | 0.733475 | 3 | 0 | 3 |
| CCDC3 | UBE4B | 0.733069 | 3 | 0 | 3 |
| CCDC3 | NR2F1 | 0.728666 | 3 | 0 | 3 |
| CCDC3 | LINC01082 | 0.726762 | 4 | 0 | 4 |
| CCDC3 | ANO10 | 0.725805 | 3 | 0 | 3 |
| CCDC3 | CLIP3 | 0.724455 | 5 | 0 | 5 |
For details and further investigation, click here
