| Full name: musashi RNA binding protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 124540 | HGNC ID: HGNC:18585 | Ensembl Gene: ENSG00000153944 | OMIM ID: 607897 |
| Drug and gene relationship at DGIdb | |||
Expression of MSI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSI2 | 124540 | 226134_s_at | -0.2709 | 0.7605 | |
| GSE26886 | MSI2 | 124540 | 226134_s_at | 0.7635 | 0.0443 | |
| GSE45670 | MSI2 | 124540 | 226134_s_at | -0.1701 | 0.5953 | |
| GSE53622 | MSI2 | 124540 | 83222 | -0.7668 | 0.0000 | |
| GSE53624 | MSI2 | 124540 | 83222 | -0.8468 | 0.0000 | |
| GSE63941 | MSI2 | 124540 | 225240_s_at | 0.4640 | 0.4794 | |
| GSE77861 | MSI2 | 124540 | 225240_s_at | 0.8286 | 0.0164 | |
| GSE97050 | MSI2 | 124540 | A_23_P44195 | -0.0908 | 0.6951 | |
| SRP007169 | MSI2 | 124540 | RNAseq | 2.2708 | 0.0001 | |
| SRP008496 | MSI2 | 124540 | RNAseq | 2.4367 | 0.0000 | |
| SRP064894 | MSI2 | 124540 | RNAseq | 0.3030 | 0.0837 | |
| SRP133303 | MSI2 | 124540 | RNAseq | 0.6137 | 0.0047 | |
| SRP159526 | MSI2 | 124540 | RNAseq | 1.1157 | 0.0018 | |
| SRP193095 | MSI2 | 124540 | RNAseq | 0.3855 | 0.0024 | |
| SRP219564 | MSI2 | 124540 | RNAseq | 0.1268 | 0.6015 | |
| TCGA | MSI2 | 124540 | RNAseq | 0.0194 | 0.8428 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MSI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MSI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MSI2 | 124540 | 5 | 1 | 24 | |
| GSE20123 | MSI2 | 124540 | 5 | 1 | 24 | |
| GSE43470 | MSI2 | 124540 | 4 | 1 | 38 | |
| GSE46452 | MSI2 | 124540 | 32 | 0 | 27 | |
| GSE47630 | MSI2 | 124540 | 7 | 1 | 32 | |
| GSE54993 | MSI2 | 124540 | 2 | 5 | 63 | |
| GSE54994 | MSI2 | 124540 | 8 | 6 | 39 | |
| GSE60625 | MSI2 | 124540 | 4 | 0 | 7 | |
| GSE74703 | MSI2 | 124540 | 4 | 1 | 31 | |
| GSE74704 | MSI2 | 124540 | 4 | 1 | 15 | |
| TCGA | MSI2 | 124540 | 27 | 7 | 62 |
Total number of gains: 102; Total number of losses: 24; Total Number of normals: 362.
Somatic mutations of MSI2:
Generating mutation plots.
Highly correlated genes for MSI2:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSI2 | ANKRD40 | 0.850909 | 3 | 0 | 3 |
| MSI2 | GOSR1 | 0.836326 | 3 | 0 | 3 |
| MSI2 | HDAC9 | 0.788975 | 3 | 0 | 3 |
| MSI2 | F8 | 0.784266 | 3 | 0 | 3 |
| MSI2 | SLC25A33 | 0.771676 | 3 | 0 | 3 |
| MSI2 | MAPRE2 | 0.769934 | 3 | 0 | 3 |
| MSI2 | ICE2 | 0.767875 | 3 | 0 | 3 |
| MSI2 | PMP22 | 0.765422 | 3 | 0 | 3 |
| MSI2 | SHPRH | 0.764882 | 3 | 0 | 3 |
| MSI2 | DYNC2LI1 | 0.761499 | 3 | 0 | 3 |
| MSI2 | RIMKLB | 0.758667 | 3 | 0 | 3 |
| MSI2 | FBXO21 | 0.755623 | 4 | 0 | 4 |
| MSI2 | C12orf57 | 0.752568 | 3 | 0 | 3 |
| MSI2 | ADAM23 | 0.752532 | 3 | 0 | 3 |
| MSI2 | THAP5 | 0.749136 | 3 | 0 | 3 |
| MSI2 | IRS2 | 0.744484 | 4 | 0 | 4 |
| MSI2 | STAT5B | 0.742159 | 4 | 0 | 4 |
| MSI2 | RFX7 | 0.740436 | 3 | 0 | 3 |
| MSI2 | RICTOR | 0.736178 | 3 | 0 | 3 |
| MSI2 | CORO2B | 0.729884 | 3 | 0 | 3 |
For details and further investigation, click here
