| Full name: zinc finger protein 521 | Alias Symbol: EHZF|Evi3 | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 25925 | HGNC ID: HGNC:24605 | Ensembl Gene: ENSG00000198795 | OMIM ID: 610974 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF521:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF521 | 25925 | 226677_at | -0.6549 | 0.4145 | |
| GSE26886 | ZNF521 | 25925 | 226677_at | -0.0972 | 0.7664 | |
| GSE45670 | ZNF521 | 25925 | 226676_at | -1.4439 | 0.0050 | |
| GSE53622 | ZNF521 | 25925 | 34624 | 0.0872 | 0.5918 | |
| GSE53624 | ZNF521 | 25925 | 34624 | 0.0540 | 0.6465 | |
| GSE63941 | ZNF521 | 25925 | 226676_at | -5.5224 | 0.0000 | |
| GSE77861 | ZNF521 | 25925 | 226676_at | 0.0267 | 0.8480 | |
| GSE97050 | ZNF521 | 25925 | A_33_P3219398 | 0.2127 | 0.5996 | |
| SRP007169 | ZNF521 | 25925 | RNAseq | 1.3874 | 0.0104 | |
| SRP008496 | ZNF521 | 25925 | RNAseq | 1.8209 | 0.0001 | |
| SRP064894 | ZNF521 | 25925 | RNAseq | 0.5876 | 0.1042 | |
| SRP133303 | ZNF521 | 25925 | RNAseq | -0.2091 | 0.5422 | |
| SRP193095 | ZNF521 | 25925 | RNAseq | 0.7336 | 0.0074 | |
| SRP219564 | ZNF521 | 25925 | RNAseq | 0.4857 | 0.4653 | |
| TCGA | ZNF521 | 25925 | RNAseq | -0.1026 | 0.5497 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by ZNF521 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF521:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF521 | 25925 | 1 | 6 | 23 | |
| GSE20123 | ZNF521 | 25925 | 1 | 6 | 23 | |
| GSE43470 | ZNF521 | 25925 | 1 | 2 | 40 | |
| GSE46452 | ZNF521 | 25925 | 3 | 24 | 32 | |
| GSE47630 | ZNF521 | 25925 | 6 | 19 | 15 | |
| GSE54993 | ZNF521 | 25925 | 7 | 1 | 62 | |
| GSE54994 | ZNF521 | 25925 | 3 | 14 | 36 | |
| GSE60625 | ZNF521 | 25925 | 0 | 4 | 7 | |
| GSE74703 | ZNF521 | 25925 | 1 | 2 | 33 | |
| GSE74704 | ZNF521 | 25925 | 1 | 5 | 14 | |
| TCGA | ZNF521 | 25925 | 16 | 31 | 49 |
Total number of gains: 40; Total number of losses: 114; Total Number of normals: 334.
Somatic mutations of ZNF521:
Generating mutation plots.
Highly correlated genes for ZNF521:
Showing top 20/727 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF521 | SMPD1 | 0.87242 | 3 | 0 | 3 |
| ZNF521 | CNRIP1 | 0.82808 | 7 | 0 | 7 |
| ZNF521 | ARF4 | 0.80857 | 3 | 0 | 3 |
| ZNF521 | DZIP1L | 0.786309 | 3 | 0 | 3 |
| ZNF521 | NFIC | 0.758713 | 3 | 0 | 3 |
| ZNF521 | FIBIN | 0.757545 | 5 | 0 | 5 |
| ZNF521 | ACO1 | 0.757388 | 3 | 0 | 3 |
| ZNF521 | UNC5C | 0.747836 | 5 | 0 | 5 |
| ZNF521 | ZEB2 | 0.746643 | 7 | 0 | 7 |
| ZNF521 | AK3 | 0.745279 | 3 | 0 | 3 |
| ZNF521 | LYSMD3 | 0.738894 | 3 | 0 | 3 |
| ZNF521 | SNX12 | 0.73323 | 3 | 0 | 3 |
| ZNF521 | ITFG1 | 0.732625 | 3 | 0 | 3 |
| ZNF521 | A1BG | 0.725763 | 3 | 0 | 3 |
| ZNF521 | AIDA | 0.720817 | 3 | 0 | 3 |
| ZNF521 | MOSPD1 | 0.718864 | 3 | 0 | 3 |
| ZNF521 | RARRES2 | 0.717987 | 7 | 0 | 7 |
| ZNF521 | S1PR1 | 0.716686 | 6 | 0 | 5 |
| ZNF521 | C11orf96 | 0.71271 | 4 | 0 | 4 |
| ZNF521 | TPSB2 | 0.711752 | 3 | 0 | 3 |
For details and further investigation, click here
