STEAP4

 

Full name: STEAP4 metalloreductase Alias Symbol: FLJ23153|TIARP|STAMP2|SchLAH
Type: protein-coding gene Cytoband: 7q21.12
Entrez ID: 79689 HGNC ID: HGNC:21923 Ensembl Gene: ENSG00000127954 OMIM ID: 611098
Drug and gene relationship at DGIdb

 

Expression of STEAP4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STEAP4 79689 225987_at -0.8247 0.1501
GSE20347 STEAP4 79689 220187_at -0.4534 0.0588
GSE23400 STEAP4 79689 220187_at -0.2304 0.0000
GSE26886 STEAP4 79689 225987_at -2.7052 0.0011
GSE29001 STEAP4 79689 220187_at -0.0445 0.9157
GSE38129 STEAP4 79689 220187_at -0.5820 0.0028
GSE45670 STEAP4 79689 225987_at -0.4872 0.2624
GSE53622 STEAP4 79689 108183 -1.9625 0.0000
GSE53624 STEAP4 79689 108183 -2.0964 0.0000
GSE63941 STEAP4 79689 225987_at 1.9654 0.3383
GSE77861 STEAP4 79689 225987_at -0.9174 0.2083
GSE97050 STEAP4 79689 A_33_P3318322 0.3509 0.3775
SRP007169 STEAP4 79689 RNAseq -2.1294 0.0033
SRP064894 STEAP4 79689 RNAseq -0.0826 0.8629
SRP133303 STEAP4 79689 RNAseq -0.7509 0.0155
SRP159526 STEAP4 79689 RNAseq -1.6825 0.0145
SRP193095 STEAP4 79689 RNAseq -0.1166 0.7524
SRP219564 STEAP4 79689 RNAseq 0.5372 0.5494
TCGA STEAP4 79689 RNAseq -0.3482 0.2003

Upregulated datasets: 0; Downregulated datasets: 5.  

 

Survival by STEAP4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of STEAP4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STEAP4 79689 12 1 17
GSE20123 STEAP4 79689 12 1 17
GSE43470 STEAP4 79689 5 1 37
GSE46452 STEAP4 79689 12 0 47
GSE47630 STEAP4 79689 8 2 30
GSE54993 STEAP4 79689 3 6 61
GSE54994 STEAP4 79689 17 2 34
GSE60625 STEAP4 79689 0 0 11
GSE74703 STEAP4 79689 4 1 31
GSE74704 STEAP4 79689 8 1 11
TCGA STEAP4 79689 53 4 39

Total number of gains: 134; Total number of losses: 19; Total Number of normals: 335.  

 

Somatic mutations of STEAP4:

 

Generating mutation plots.

 

Highly correlated genes for STEAP4:

 

Showing top 20/574 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STEAP4KCTD180.751082303
STEAP4TXNDC110.72132303
STEAP4TMEM1860.716376303
STEAP4BIRC30.713684303
STEAP4BNIP30.711021303
STEAP4LXN0.704146303
STEAP4C22orf310.700052303
STEAP4PXK0.680055303
STEAP4SETD20.676413303
STEAP4LYVE10.672061403
STEAP4CD470.660178403
STEAP4NAALADL10.655749303
STEAP4LYRM70.65254404
STEAP4PHYHD10.650563403
STEAP4ESYT20.648276403
STEAP4ARRDC30.646162706
STEAP4CLEC3B0.642082303
STEAP4CLU0.640924403
STEAP4ZMYM60.640257403
STEAP4KLHDC8B0.636823606

For details and further investigation, click here