| Full name: leucine zipper transcription factor like 1 | Alias Symbol: BBS17 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 54585 | HGNC ID: HGNC:6741 | Ensembl Gene: ENSG00000163818 | OMIM ID: 606568 |
| Drug and gene relationship at DGIdb | |||
Expression of LZTFL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LZTFL1 | 54585 | 218437_s_at | -0.4778 | 0.5955 | |
| GSE20347 | LZTFL1 | 54585 | 218437_s_at | -0.4163 | 0.0616 | |
| GSE23400 | LZTFL1 | 54585 | 218437_s_at | 0.0472 | 0.5955 | |
| GSE26886 | LZTFL1 | 54585 | 218437_s_at | 0.1167 | 0.6711 | |
| GSE29001 | LZTFL1 | 54585 | 218437_s_at | -0.2692 | 0.5658 | |
| GSE38129 | LZTFL1 | 54585 | 218437_s_at | -0.4226 | 0.0443 | |
| GSE45670 | LZTFL1 | 54585 | 218437_s_at | -0.8825 | 0.0000 | |
| GSE53622 | LZTFL1 | 54585 | 123579 | -0.3426 | 0.0000 | |
| GSE53624 | LZTFL1 | 54585 | 123579 | -0.3251 | 0.0000 | |
| GSE63941 | LZTFL1 | 54585 | 222632_s_at | 0.2057 | 0.6704 | |
| GSE77861 | LZTFL1 | 54585 | 222632_s_at | -0.3525 | 0.0254 | |
| GSE97050 | LZTFL1 | 54585 | A_24_P37519 | -0.2362 | 0.3390 | |
| SRP007169 | LZTFL1 | 54585 | RNAseq | -0.2744 | 0.5393 | |
| SRP008496 | LZTFL1 | 54585 | RNAseq | 0.3155 | 0.3327 | |
| SRP064894 | LZTFL1 | 54585 | RNAseq | -0.1451 | 0.3424 | |
| SRP133303 | LZTFL1 | 54585 | RNAseq | -0.1541 | 0.3314 | |
| SRP159526 | LZTFL1 | 54585 | RNAseq | -0.2108 | 0.2819 | |
| SRP193095 | LZTFL1 | 54585 | RNAseq | -0.3338 | 0.0070 | |
| SRP219564 | LZTFL1 | 54585 | RNAseq | -0.5286 | 0.0932 | |
| TCGA | LZTFL1 | 54585 | RNAseq | -0.1243 | 0.0474 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LZTFL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LZTFL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LZTFL1 | 54585 | 0 | 17 | 13 | |
| GSE20123 | LZTFL1 | 54585 | 0 | 18 | 12 | |
| GSE43470 | LZTFL1 | 54585 | 0 | 20 | 23 | |
| GSE46452 | LZTFL1 | 54585 | 2 | 17 | 40 | |
| GSE47630 | LZTFL1 | 54585 | 2 | 23 | 15 | |
| GSE54993 | LZTFL1 | 54585 | 7 | 2 | 61 | |
| GSE54994 | LZTFL1 | 54585 | 0 | 36 | 17 | |
| GSE60625 | LZTFL1 | 54585 | 5 | 0 | 6 | |
| GSE74703 | LZTFL1 | 54585 | 0 | 15 | 21 | |
| GSE74704 | LZTFL1 | 54585 | 0 | 12 | 8 | |
| TCGA | LZTFL1 | 54585 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of LZTFL1:
Generating mutation plots.
Highly correlated genes for LZTFL1:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LZTFL1 | RNF125 | 0.699162 | 4 | 0 | 3 |
| LZTFL1 | TRAPPC8 | 0.685817 | 3 | 0 | 3 |
| LZTFL1 | ZNF44 | 0.683679 | 3 | 0 | 3 |
| LZTFL1 | C6orf89 | 0.679645 | 4 | 0 | 4 |
| LZTFL1 | MTFR1L | 0.669246 | 4 | 0 | 3 |
| LZTFL1 | KIF9 | 0.663183 | 4 | 0 | 3 |
| LZTFL1 | ISCU | 0.658959 | 5 | 0 | 5 |
| LZTFL1 | CELF6 | 0.6587 | 3 | 0 | 3 |
| LZTFL1 | SLAIN1 | 0.651562 | 5 | 0 | 5 |
| LZTFL1 | ECHS1 | 0.650133 | 4 | 0 | 3 |
| LZTFL1 | ZNF615 | 0.64926 | 6 | 0 | 5 |
| LZTFL1 | ARL16 | 0.647116 | 3 | 0 | 3 |
| LZTFL1 | ZFYVE1 | 0.64658 | 3 | 0 | 3 |
| LZTFL1 | RABL3 | 0.646344 | 5 | 0 | 5 |
| LZTFL1 | CASQ2 | 0.645283 | 5 | 0 | 5 |
| LZTFL1 | FIBIN | 0.643606 | 3 | 0 | 3 |
| LZTFL1 | KCNT2 | 0.637341 | 6 | 0 | 5 |
| LZTFL1 | ADCY6 | 0.636805 | 4 | 0 | 3 |
| LZTFL1 | RAB28 | 0.636435 | 4 | 0 | 3 |
| LZTFL1 | IGIP | 0.636394 | 4 | 0 | 4 |
For details and further investigation, click here
