| Full name: chromosome 6 open reading frame 89 | Alias Symbol: FLJ25357|BRAP | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 221477 | HGNC ID: HGNC:21114 | Ensembl Gene: ENSG00000198663 | OMIM ID: 616642 |
| Drug and gene relationship at DGIdb | |||
Expression of C6orf89:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C6orf89 | 221477 | 224977_at | -0.1410 | 0.8303 | |
| GSE26886 | C6orf89 | 221477 | 224988_at | -0.8299 | 0.0003 | |
| GSE45670 | C6orf89 | 221477 | 224977_at | -0.2679 | 0.0586 | |
| GSE53622 | C6orf89 | 221477 | 18823 | -0.1551 | 0.0403 | |
| GSE53624 | C6orf89 | 221477 | 18823 | -0.0132 | 0.8929 | |
| GSE63941 | C6orf89 | 221477 | 224988_at | -0.3086 | 0.4021 | |
| GSE77861 | C6orf89 | 221477 | 225729_at | -0.0674 | 0.5963 | |
| GSE97050 | C6orf89 | 221477 | A_33_P3215028 | -0.4186 | 0.1464 | |
| SRP007169 | C6orf89 | 221477 | RNAseq | -0.2407 | 0.5185 | |
| SRP008496 | C6orf89 | 221477 | RNAseq | -0.1684 | 0.3977 | |
| SRP064894 | C6orf89 | 221477 | RNAseq | 0.0118 | 0.9222 | |
| SRP133303 | C6orf89 | 221477 | RNAseq | -0.1201 | 0.3383 | |
| SRP159526 | C6orf89 | 221477 | RNAseq | -0.2957 | 0.1587 | |
| SRP193095 | C6orf89 | 221477 | RNAseq | -0.1744 | 0.0524 | |
| SRP219564 | C6orf89 | 221477 | RNAseq | 0.0119 | 0.9637 | |
| TCGA | C6orf89 | 221477 | RNAseq | -0.2284 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C6orf89 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C6orf89:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C6orf89 | 221477 | 6 | 0 | 24 | |
| GSE20123 | C6orf89 | 221477 | 6 | 0 | 24 | |
| GSE43470 | C6orf89 | 221477 | 5 | 1 | 37 | |
| GSE46452 | C6orf89 | 221477 | 2 | 9 | 48 | |
| GSE47630 | C6orf89 | 221477 | 8 | 4 | 28 | |
| GSE54993 | C6orf89 | 221477 | 3 | 1 | 66 | |
| GSE54994 | C6orf89 | 221477 | 10 | 5 | 38 | |
| GSE60625 | C6orf89 | 221477 | 1 | 0 | 10 | |
| GSE74703 | C6orf89 | 221477 | 5 | 0 | 31 | |
| GSE74704 | C6orf89 | 221477 | 3 | 0 | 17 | |
| TCGA | C6orf89 | 221477 | 15 | 15 | 66 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of C6orf89:
Generating mutation plots.
Highly correlated genes for C6orf89:
Showing top 20/323 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C6orf89 | TACC2 | 0.783157 | 3 | 0 | 3 |
| C6orf89 | TSHZ1 | 0.755932 | 3 | 0 | 3 |
| C6orf89 | TCEA3 | 0.754457 | 3 | 0 | 3 |
| C6orf89 | LYRM1 | 0.754392 | 3 | 0 | 3 |
| C6orf89 | STK40 | 0.746783 | 3 | 0 | 3 |
| C6orf89 | MKRN1 | 0.742591 | 3 | 0 | 3 |
| C6orf89 | CUL1 | 0.736933 | 3 | 0 | 3 |
| C6orf89 | TMEM159 | 0.724308 | 3 | 0 | 3 |
| C6orf89 | GLUD1 | 0.723111 | 3 | 0 | 3 |
| C6orf89 | ASB8 | 0.720489 | 3 | 0 | 3 |
| C6orf89 | LSS | 0.718717 | 3 | 0 | 3 |
| C6orf89 | KLHDC8B | 0.711751 | 3 | 0 | 3 |
| C6orf89 | CAMK2G | 0.709085 | 3 | 0 | 3 |
| C6orf89 | XK | 0.702986 | 3 | 0 | 3 |
| C6orf89 | SLC9A9 | 0.702565 | 3 | 0 | 3 |
| C6orf89 | MAGI1 | 0.699865 | 3 | 0 | 3 |
| C6orf89 | ZNF564 | 0.69706 | 3 | 0 | 3 |
| C6orf89 | MFSD6 | 0.696991 | 3 | 0 | 3 |
| C6orf89 | COBL | 0.691975 | 3 | 0 | 3 |
| C6orf89 | VPS26B | 0.690672 | 4 | 0 | 3 |
For details and further investigation, click here
