| Full name: zinc finger FYVE-type containing 1 | Alias Symbol: DFCP1|KIAA1589|TAFF1|PPP1R172 | ||
| Type: protein-coding gene | Cytoband: 14q24.2 | ||
| Entrez ID: 53349 | HGNC ID: HGNC:13180 | Ensembl Gene: ENSG00000165861 | OMIM ID: 605471 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFYVE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFYVE1 | 53349 | 223387_at | -0.2570 | 0.6120 | |
| GSE26886 | ZFYVE1 | 53349 | 223387_at | -1.1967 | 0.0000 | |
| GSE45670 | ZFYVE1 | 53349 | 223387_at | -0.3075 | 0.0103 | |
| GSE53622 | ZFYVE1 | 53349 | 95469 | -0.4126 | 0.0000 | |
| GSE53624 | ZFYVE1 | 53349 | 95469 | -0.5656 | 0.0000 | |
| GSE63941 | ZFYVE1 | 53349 | 223387_at | -0.9893 | 0.0188 | |
| GSE77861 | ZFYVE1 | 53349 | 223387_at | -0.4133 | 0.2068 | |
| GSE97050 | ZFYVE1 | 53349 | A_23_P128956 | -0.6616 | 0.1805 | |
| SRP007169 | ZFYVE1 | 53349 | RNAseq | -2.3114 | 0.0000 | |
| SRP008496 | ZFYVE1 | 53349 | RNAseq | -1.8982 | 0.0000 | |
| SRP064894 | ZFYVE1 | 53349 | RNAseq | -0.5902 | 0.0005 | |
| SRP133303 | ZFYVE1 | 53349 | RNAseq | -0.3854 | 0.1146 | |
| SRP159526 | ZFYVE1 | 53349 | RNAseq | -0.6542 | 0.0177 | |
| SRP193095 | ZFYVE1 | 53349 | RNAseq | -1.0177 | 0.0000 | |
| SRP219564 | ZFYVE1 | 53349 | RNAseq | -0.4900 | 0.1642 | |
| TCGA | ZFYVE1 | 53349 | RNAseq | -0.0708 | 0.2151 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZFYVE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFYVE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFYVE1 | 53349 | 8 | 2 | 20 | |
| GSE20123 | ZFYVE1 | 53349 | 8 | 2 | 20 | |
| GSE43470 | ZFYVE1 | 53349 | 8 | 3 | 32 | |
| GSE46452 | ZFYVE1 | 53349 | 16 | 3 | 40 | |
| GSE47630 | ZFYVE1 | 53349 | 11 | 8 | 21 | |
| GSE54993 | ZFYVE1 | 53349 | 3 | 8 | 59 | |
| GSE54994 | ZFYVE1 | 53349 | 19 | 4 | 30 | |
| GSE60625 | ZFYVE1 | 53349 | 0 | 2 | 9 | |
| GSE74703 | ZFYVE1 | 53349 | 7 | 3 | 26 | |
| GSE74704 | ZFYVE1 | 53349 | 3 | 2 | 15 | |
| TCGA | ZFYVE1 | 53349 | 31 | 16 | 49 |
Total number of gains: 114; Total number of losses: 53; Total Number of normals: 321.
Somatic mutations of ZFYVE1:
Generating mutation plots.
Highly correlated genes for ZFYVE1:
Showing top 20/932 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFYVE1 | ZNF565 | 0.789222 | 3 | 0 | 3 |
| ZFYVE1 | ZNF383 | 0.782468 | 3 | 0 | 3 |
| ZFYVE1 | CCNYL1 | 0.780299 | 3 | 0 | 3 |
| ZFYVE1 | SLC12A6 | 0.757884 | 3 | 0 | 3 |
| ZFYVE1 | RYBP | 0.752831 | 3 | 0 | 3 |
| ZFYVE1 | C15orf41 | 0.751776 | 3 | 0 | 3 |
| ZFYVE1 | TRAPPC2 | 0.735911 | 3 | 0 | 3 |
| ZFYVE1 | ADCK1 | 0.730668 | 3 | 0 | 3 |
| ZFYVE1 | ANO8 | 0.726373 | 3 | 0 | 3 |
| ZFYVE1 | AKAP17A | 0.724924 | 3 | 0 | 3 |
| ZFYVE1 | TRIP11 | 0.724909 | 4 | 0 | 4 |
| ZFYVE1 | FAM122C | 0.72487 | 4 | 0 | 4 |
| ZFYVE1 | KIAA1143 | 0.720309 | 3 | 0 | 3 |
| ZFYVE1 | PRDM2 | 0.719585 | 4 | 0 | 3 |
| ZFYVE1 | IPO8 | 0.716018 | 3 | 0 | 3 |
| ZFYVE1 | ZFYVE21 | 0.714792 | 7 | 0 | 7 |
| ZFYVE1 | GTF3C1 | 0.714293 | 5 | 0 | 5 |
| ZFYVE1 | TMEM50A | 0.713828 | 3 | 0 | 3 |
| ZFYVE1 | ZMAT3 | 0.710666 | 3 | 0 | 3 |
| ZFYVE1 | EIF4G3 | 0.710087 | 3 | 0 | 3 |
For details and further investigation, click here
