| Full name: RAB28, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p15.33 | ||
| Entrez ID: 9364 | HGNC ID: HGNC:9768 | Ensembl Gene: ENSG00000157869 | OMIM ID: 612994 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RAB28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB28 | 9364 | 227003_at | 0.1700 | 0.5249 | |
| GSE20347 | RAB28 | 9364 | 207495_at | 0.0554 | 0.4629 | |
| GSE23400 | RAB28 | 9364 | 207495_at | -0.0236 | 0.2832 | |
| GSE26886 | RAB28 | 9364 | 227003_at | 0.1456 | 0.5298 | |
| GSE29001 | RAB28 | 9364 | 207495_at | 0.0837 | 0.4023 | |
| GSE38129 | RAB28 | 9364 | 207495_at | 0.1123 | 0.1443 | |
| GSE45670 | RAB28 | 9364 | 227003_at | -0.3232 | 0.0095 | |
| GSE53622 | RAB28 | 9364 | 77875 | 0.2237 | 0.0022 | |
| GSE53624 | RAB28 | 9364 | 77875 | -0.0539 | 0.4052 | |
| GSE63941 | RAB28 | 9364 | 227003_at | -0.2715 | 0.5542 | |
| GSE77861 | RAB28 | 9364 | 227003_at | -0.1351 | 0.6893 | |
| GSE97050 | RAB28 | 9364 | A_33_P3349325 | 0.0132 | 0.9569 | |
| SRP007169 | RAB28 | 9364 | RNAseq | 0.1402 | 0.7601 | |
| SRP008496 | RAB28 | 9364 | RNAseq | 0.3541 | 0.2379 | |
| SRP064894 | RAB28 | 9364 | RNAseq | 0.0201 | 0.9048 | |
| SRP133303 | RAB28 | 9364 | RNAseq | -0.0297 | 0.8547 | |
| SRP159526 | RAB28 | 9364 | RNAseq | 0.0485 | 0.8611 | |
| SRP193095 | RAB28 | 9364 | RNAseq | -0.3307 | 0.0012 | |
| SRP219564 | RAB28 | 9364 | RNAseq | 0.0256 | 0.9364 | |
| TCGA | RAB28 | 9364 | RNAseq | -0.0782 | 0.2350 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAB28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB28 | 9364 | 0 | 18 | 12 | |
| GSE20123 | RAB28 | 9364 | 0 | 18 | 12 | |
| GSE43470 | RAB28 | 9364 | 1 | 15 | 27 | |
| GSE46452 | RAB28 | 9364 | 1 | 36 | 22 | |
| GSE47630 | RAB28 | 9364 | 0 | 20 | 20 | |
| GSE54993 | RAB28 | 9364 | 10 | 0 | 60 | |
| GSE54994 | RAB28 | 9364 | 4 | 12 | 37 | |
| GSE60625 | RAB28 | 9364 | 0 | 0 | 11 | |
| GSE74703 | RAB28 | 9364 | 1 | 13 | 22 | |
| GSE74704 | RAB28 | 9364 | 0 | 11 | 9 | |
| TCGA | RAB28 | 9364 | 9 | 48 | 39 |
Total number of gains: 26; Total number of losses: 191; Total Number of normals: 271.
Somatic mutations of RAB28:
Generating mutation plots.
Highly correlated genes for RAB28:
Showing top 20/221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB28 | CCDC59 | 0.737816 | 3 | 0 | 3 |
| RAB28 | PCID2 | 0.728053 | 3 | 0 | 3 |
| RAB28 | ZNF140 | 0.724636 | 3 | 0 | 3 |
| RAB28 | MUS81 | 0.714724 | 3 | 0 | 3 |
| RAB28 | ZBTB2 | 0.710769 | 3 | 0 | 3 |
| RAB28 | DTX3 | 0.710543 | 3 | 0 | 3 |
| RAB28 | NBN | 0.710171 | 3 | 0 | 3 |
| RAB28 | ZNF136 | 0.70129 | 3 | 0 | 3 |
| RAB28 | WDR1 | 0.7008 | 5 | 0 | 5 |
| RAB28 | CLN5 | 0.695662 | 3 | 0 | 3 |
| RAB28 | RFX5 | 0.689516 | 3 | 0 | 3 |
| RAB28 | ZNF496 | 0.686675 | 3 | 0 | 3 |
| RAB28 | TMSB15B | 0.680958 | 3 | 0 | 3 |
| RAB28 | ZNF791 | 0.678179 | 3 | 0 | 3 |
| RAB28 | MRFAP1 | 0.67599 | 6 | 0 | 5 |
| RAB28 | IPO11 | 0.668111 | 3 | 0 | 3 |
| RAB28 | NTN4 | 0.666255 | 4 | 0 | 3 |
| RAB28 | PARVB | 0.666159 | 3 | 0 | 3 |
| RAB28 | CRTAP | 0.66594 | 3 | 0 | 3 |
| RAB28 | PKNOX1 | 0.665629 | 4 | 0 | 3 |
For details and further investigation, click here
