| Full name: mucosal vascular addressin cell adhesion molecule 1 | Alias Symbol: MACAM1 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 8174 | HGNC ID: HGNC:6765 | Ensembl Gene: ENSG00000099866 | OMIM ID: 102670 |
| Drug and gene relationship at DGIdb | |||
Expression of MADCAM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MADCAM1 | 8174 | 208037_s_at | -0.1877 | 0.6833 | |
| GSE20347 | MADCAM1 | 8174 | 208037_s_at | -0.1328 | 0.2701 | |
| GSE23400 | MADCAM1 | 8174 | 208037_s_at | -0.1742 | 0.0000 | |
| GSE26886 | MADCAM1 | 8174 | 208037_s_at | -0.2227 | 0.1200 | |
| GSE29001 | MADCAM1 | 8174 | 208037_s_at | -0.3094 | 0.0088 | |
| GSE38129 | MADCAM1 | 8174 | 208037_s_at | -0.3498 | 0.0047 | |
| GSE45670 | MADCAM1 | 8174 | 208037_s_at | 0.0019 | 0.9938 | |
| GSE53622 | MADCAM1 | 8174 | 68097 | -1.4350 | 0.0000 | |
| GSE53624 | MADCAM1 | 8174 | 68097 | -1.4381 | 0.0000 | |
| GSE63941 | MADCAM1 | 8174 | 208037_s_at | 0.1491 | 0.3494 | |
| GSE77861 | MADCAM1 | 8174 | 208037_s_at | -0.0849 | 0.4745 | |
| SRP133303 | MADCAM1 | 8174 | RNAseq | -2.4025 | 0.0000 | |
| SRP219564 | MADCAM1 | 8174 | RNAseq | 0.1846 | 0.8317 | |
| TCGA | MADCAM1 | 8174 | RNAseq | -2.3891 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MADCAM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MADCAM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MADCAM1 | 8174 | 6 | 6 | 18 | |
| GSE20123 | MADCAM1 | 8174 | 6 | 5 | 19 | |
| GSE43470 | MADCAM1 | 8174 | 1 | 10 | 32 | |
| GSE46452 | MADCAM1 | 8174 | 47 | 1 | 11 | |
| GSE47630 | MADCAM1 | 8174 | 5 | 7 | 28 | |
| GSE54993 | MADCAM1 | 8174 | 13 | 4 | 53 | |
| GSE54994 | MADCAM1 | 8174 | 8 | 15 | 30 | |
| GSE60625 | MADCAM1 | 8174 | 9 | 0 | 2 | |
| GSE74703 | MADCAM1 | 8174 | 1 | 7 | 28 | |
| GSE74704 | MADCAM1 | 8174 | 5 | 3 | 12 | |
| TCGA | MADCAM1 | 8174 | 8 | 25 | 63 |
Total number of gains: 109; Total number of losses: 83; Total Number of normals: 296.
Somatic mutations of MADCAM1:
Generating mutation plots.
Highly correlated genes for MADCAM1:
Showing top 20/466 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MADCAM1 | ANGPTL6 | 0.753393 | 3 | 0 | 3 |
| MADCAM1 | DEFB118 | 0.673964 | 4 | 0 | 4 |
| MADCAM1 | ADM2 | 0.6473 | 4 | 0 | 4 |
| MADCAM1 | EXOC3L2 | 0.639537 | 3 | 0 | 3 |
| MADCAM1 | MS4A7 | 0.632415 | 3 | 0 | 3 |
| MADCAM1 | LINC01312 | 0.630697 | 4 | 0 | 3 |
| MADCAM1 | EDA2R | 0.629038 | 6 | 0 | 6 |
| MADCAM1 | LINC00924 | 0.628922 | 3 | 0 | 3 |
| MADCAM1 | IFNA10 | 0.627997 | 5 | 0 | 4 |
| MADCAM1 | SHBG | 0.626927 | 4 | 0 | 4 |
| MADCAM1 | LINC01215 | 0.625205 | 5 | 0 | 4 |
| MADCAM1 | BTN1A1 | 0.622953 | 4 | 0 | 4 |
| MADCAM1 | MVK | 0.620488 | 7 | 0 | 6 |
| MADCAM1 | CD1B | 0.619436 | 8 | 0 | 7 |
| MADCAM1 | TPSG1 | 0.618429 | 5 | 0 | 4 |
| MADCAM1 | ADAM30 | 0.617256 | 4 | 0 | 4 |
| MADCAM1 | PHF7 | 0.611683 | 5 | 0 | 5 |
| MADCAM1 | IL17RC | 0.610589 | 6 | 0 | 5 |
| MADCAM1 | SLAMF6 | 0.610491 | 6 | 0 | 5 |
| MADCAM1 | SLC10A2 | 0.609934 | 4 | 0 | 4 |
For details and further investigation, click here
