| Full name: adrenomedullin 2 | Alias Symbol: AM2|FLJ21135 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 79924 | HGNC ID: HGNC:28898 | Ensembl Gene: ENSG00000128165 | OMIM ID: 608682 |
| Drug and gene relationship at DGIdb | |||
Expression of ADM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADM2 | 79924 | 220538_at | 0.0156 | 0.9548 | |
| GSE20347 | ADM2 | 79924 | 220538_at | -0.0767 | 0.4562 | |
| GSE23400 | ADM2 | 79924 | 220538_at | -0.2423 | 0.0000 | |
| GSE26886 | ADM2 | 79924 | 220538_at | 0.0452 | 0.6333 | |
| GSE29001 | ADM2 | 79924 | 220538_at | -0.3448 | 0.0537 | |
| GSE38129 | ADM2 | 79924 | 220538_at | -0.1642 | 0.0382 | |
| GSE45670 | ADM2 | 79924 | 220538_at | -0.1364 | 0.1758 | |
| GSE53622 | ADM2 | 79924 | 9154 | 0.0047 | 0.9509 | |
| GSE53624 | ADM2 | 79924 | 9154 | -0.5275 | 0.0000 | |
| GSE63941 | ADM2 | 79924 | 220538_at | -0.0795 | 0.6016 | |
| GSE77861 | ADM2 | 79924 | 220538_at | -0.0805 | 0.4827 | |
| GSE97050 | ADM2 | 79924 | A_33_P3413910 | 0.0097 | 0.9694 | |
| SRP007169 | ADM2 | 79924 | RNAseq | 0.2959 | 0.6716 | |
| SRP064894 | ADM2 | 79924 | RNAseq | 0.5818 | 0.1934 | |
| SRP133303 | ADM2 | 79924 | RNAseq | 0.1153 | 0.7594 | |
| SRP193095 | ADM2 | 79924 | RNAseq | 0.2374 | 0.2994 | |
| SRP219564 | ADM2 | 79924 | RNAseq | 0.3188 | 0.7302 | |
| TCGA | ADM2 | 79924 | RNAseq | -0.1478 | 0.4134 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADM2 | 79924 | 3 | 8 | 19 | |
| GSE20123 | ADM2 | 79924 | 3 | 8 | 19 | |
| GSE43470 | ADM2 | 79924 | 2 | 8 | 33 | |
| GSE46452 | ADM2 | 79924 | 31 | 2 | 26 | |
| GSE47630 | ADM2 | 79924 | 9 | 4 | 27 | |
| GSE54993 | ADM2 | 79924 | 4 | 6 | 60 | |
| GSE54994 | ADM2 | 79924 | 11 | 8 | 34 | |
| GSE60625 | ADM2 | 79924 | 5 | 0 | 6 | |
| GSE74703 | ADM2 | 79924 | 2 | 6 | 28 | |
| GSE74704 | ADM2 | 79924 | 1 | 4 | 15 | |
| TCGA | ADM2 | 79924 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of ADM2:
Generating mutation plots.
Highly correlated genes for ADM2:
Showing top 20/1393 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADM2 | RAD52 | 0.859089 | 3 | 0 | 3 |
| ADM2 | RCOR2 | 0.798019 | 3 | 0 | 3 |
| ADM2 | SALL3 | 0.792844 | 3 | 0 | 3 |
| ADM2 | CELF5 | 0.7797 | 3 | 0 | 3 |
| ADM2 | ZNF329 | 0.77722 | 3 | 0 | 3 |
| ADM2 | MGAT5B | 0.776579 | 3 | 0 | 3 |
| ADM2 | SCARA5 | 0.765791 | 3 | 0 | 3 |
| ADM2 | STRC | 0.763611 | 3 | 0 | 3 |
| ADM2 | GDF7 | 0.750634 | 3 | 0 | 3 |
| ADM2 | NKX2-8 | 0.750268 | 4 | 0 | 4 |
| ADM2 | YY2 | 0.745909 | 3 | 0 | 3 |
| ADM2 | EPX | 0.744769 | 6 | 0 | 6 |
| ADM2 | KRTAP5-9 | 0.741027 | 4 | 0 | 4 |
| ADM2 | POLM | 0.737389 | 4 | 0 | 3 |
| ADM2 | BEST4 | 0.73339 | 3 | 0 | 3 |
| ADM2 | LMAN1L | 0.733216 | 8 | 0 | 8 |
| ADM2 | DCDC1 | 0.730408 | 3 | 0 | 3 |
| ADM2 | MYBPH | 0.727918 | 5 | 0 | 5 |
| ADM2 | CDH23 | 0.72617 | 4 | 0 | 3 |
| ADM2 | PLA2G2C | 0.724218 | 3 | 0 | 3 |
For details and further investigation, click here
