| Full name: angiopoietin like 6 | Alias Symbol: ARP5|AGF | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 83854 | HGNC ID: HGNC:23140 | Ensembl Gene: ENSG00000130812 | OMIM ID: 609336 |
| Drug and gene relationship at DGIdb | |||
Expression of ANGPTL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANGPTL6 | 83854 | 223967_at | -0.1550 | 0.5893 | |
| GSE26886 | ANGPTL6 | 83854 | 223967_at | 0.1487 | 0.1578 | |
| GSE45670 | ANGPTL6 | 83854 | 223967_at | 0.1340 | 0.1126 | |
| GSE63941 | ANGPTL6 | 83854 | 223967_at | 0.1092 | 0.4812 | |
| GSE77861 | ANGPTL6 | 83854 | 223967_at | -0.1194 | 0.2819 | |
| GSE97050 | ANGPTL6 | 83854 | A_23_P50276 | 0.0818 | 0.7166 | |
| SRP133303 | ANGPTL6 | 83854 | RNAseq | -0.4052 | 0.2822 | |
| SRP219564 | ANGPTL6 | 83854 | RNAseq | 1.7507 | 0.0093 | |
| TCGA | ANGPTL6 | 83854 | RNAseq | -1.7627 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ANGPTL6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ANGPTL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANGPTL6 | 83854 | 4 | 2 | 24 | |
| GSE20123 | ANGPTL6 | 83854 | 3 | 1 | 26 | |
| GSE43470 | ANGPTL6 | 83854 | 3 | 6 | 34 | |
| GSE46452 | ANGPTL6 | 83854 | 47 | 1 | 11 | |
| GSE47630 | ANGPTL6 | 83854 | 4 | 7 | 29 | |
| GSE54993 | ANGPTL6 | 83854 | 16 | 3 | 51 | |
| GSE54994 | ANGPTL6 | 83854 | 7 | 13 | 33 | |
| GSE60625 | ANGPTL6 | 83854 | 9 | 0 | 2 | |
| GSE74703 | ANGPTL6 | 83854 | 3 | 4 | 29 | |
| GSE74704 | ANGPTL6 | 83854 | 0 | 1 | 19 | |
| TCGA | ANGPTL6 | 83854 | 13 | 16 | 67 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ANGPTL6:
Generating mutation plots.
Highly correlated genes for ANGPTL6:
Showing top 20/122 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANGPTL6 | CACNB4 | 0.807545 | 3 | 0 | 3 |
| ANGPTL6 | FBXW5 | 0.803276 | 3 | 0 | 3 |
| ANGPTL6 | SLC15A3 | 0.78096 | 3 | 0 | 3 |
| ANGPTL6 | CR1L | 0.772367 | 3 | 0 | 3 |
| ANGPTL6 | MADCAM1 | 0.753393 | 3 | 0 | 3 |
| ANGPTL6 | ZNF414 | 0.749421 | 3 | 0 | 3 |
| ANGPTL6 | TTN | 0.744458 | 3 | 0 | 3 |
| ANGPTL6 | TTYH2 | 0.741594 | 3 | 0 | 3 |
| ANGPTL6 | ARSD | 0.736991 | 3 | 0 | 3 |
| ANGPTL6 | RASSF4 | 0.736336 | 3 | 0 | 3 |
| ANGPTL6 | FBXO10 | 0.735965 | 3 | 0 | 3 |
| ANGPTL6 | KRT33B | 0.727023 | 3 | 0 | 3 |
| ANGPTL6 | TMEM222 | 0.722709 | 3 | 0 | 3 |
| ANGPTL6 | COL23A1 | 0.716462 | 3 | 0 | 3 |
| ANGPTL6 | MS4A6A | 0.713807 | 3 | 0 | 3 |
| ANGPTL6 | SPI1 | 0.713575 | 3 | 0 | 3 |
| ANGPTL6 | SAMHD1 | 0.708927 | 3 | 0 | 3 |
| ANGPTL6 | SLAMF6 | 0.70843 | 3 | 0 | 3 |
| ANGPTL6 | ARHGAP44 | 0.704433 | 3 | 0 | 3 |
| ANGPTL6 | SH3KBP1 | 0.701161 | 3 | 0 | 3 |
For details and further investigation, click here
