| Full name: membrane spanning 4-domains A7 | Alias Symbol: CD20L4|CFFM4|MS4A8 | ||
| Type: protein-coding gene | Cytoband: 11q12 | ||
| Entrez ID: 58475 | HGNC ID: HGNC:13378 | Ensembl Gene: | OMIM ID: 606502 |
| Drug and gene relationship at DGIdb | |||
Expression of MS4A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MS4A7 | 58475 | 223343_at | 0.0995 | 0.9307 | |
| GSE26886 | MS4A7 | 58475 | 223344_s_at | 0.0170 | 0.9261 | |
| GSE45670 | MS4A7 | 58475 | 223343_at | -0.5736 | 0.2962 | |
| GSE53622 | MS4A7 | 58475 | 13978 | 0.2176 | 0.0560 | |
| GSE53624 | MS4A7 | 58475 | 13978 | 0.1677 | 0.1453 | |
| GSE63941 | MS4A7 | 58475 | 223344_s_at | 0.2015 | 0.2456 | |
| GSE77861 | MS4A7 | 58475 | 223344_s_at | -0.0958 | 0.6077 | |
| GSE97050 | MS4A7 | 58475 | A_33_P3352098 | 0.1163 | 0.6016 | |
| SRP007169 | MS4A7 | 58475 | RNAseq | 2.2872 | 0.0019 | |
| SRP008496 | MS4A7 | 58475 | RNAseq | 2.1823 | 0.0000 | |
| SRP064894 | MS4A7 | 58475 | RNAseq | 1.0418 | 0.0054 | |
| SRP133303 | MS4A7 | 58475 | RNAseq | 0.5464 | 0.1136 | |
| SRP159526 | MS4A7 | 58475 | RNAseq | 0.8150 | 0.2427 | |
| SRP193095 | MS4A7 | 58475 | RNAseq | 0.8923 | 0.0012 | |
| SRP219564 | MS4A7 | 58475 | RNAseq | 1.3045 | 0.0640 | |
| TCGA | MS4A7 | 58475 | RNAseq | -0.0601 | 0.6923 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MS4A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MS4A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MS4A7 | 58475 | 2 | 4 | 24 | |
| GSE20123 | MS4A7 | 58475 | 2 | 4 | 24 | |
| GSE43470 | MS4A7 | 58475 | 2 | 5 | 36 | |
| GSE46452 | MS4A7 | 58475 | 8 | 4 | 47 | |
| GSE47630 | MS4A7 | 58475 | 3 | 8 | 29 | |
| GSE54993 | MS4A7 | 58475 | 3 | 0 | 67 | |
| GSE54994 | MS4A7 | 58475 | 5 | 5 | 43 | |
| GSE60625 | MS4A7 | 58475 | 0 | 3 | 8 | |
| GSE74703 | MS4A7 | 58475 | 2 | 3 | 31 | |
| GSE74704 | MS4A7 | 58475 | 2 | 3 | 15 | |
| TCGA | MS4A7 | 58475 | 14 | 10 | 72 |
Total number of gains: 43; Total number of losses: 49; Total Number of normals: 396.
Somatic mutations of MS4A7:
Generating mutation plots.
Highly correlated genes for MS4A7:
Showing top 20/143 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MS4A7 | CMKLR1 | 0.902408 | 3 | 0 | 3 |
| MS4A7 | LAPTM5 | 0.821069 | 3 | 0 | 3 |
| MS4A7 | CYBB | 0.782414 | 4 | 0 | 4 |
| MS4A7 | C1QA | 0.774921 | 4 | 0 | 4 |
| MS4A7 | SLC7A7 | 0.759685 | 4 | 0 | 4 |
| MS4A7 | MPEG1 | 0.732198 | 4 | 0 | 3 |
| MS4A7 | GIMAP2 | 0.732151 | 4 | 0 | 4 |
| MS4A7 | C1QB | 0.720529 | 5 | 0 | 4 |
| MS4A7 | CCR1 | 0.718696 | 4 | 0 | 4 |
| MS4A7 | GIMAP4 | 0.71751 | 4 | 0 | 4 |
| MS4A7 | GPR34 | 0.697148 | 5 | 0 | 5 |
| MS4A7 | RNASE6 | 0.695576 | 4 | 0 | 4 |
| MS4A7 | ITGAM | 0.693136 | 4 | 0 | 4 |
| MS4A7 | EVI2A | 0.689542 | 4 | 0 | 3 |
| MS4A7 | FYN | 0.687984 | 3 | 0 | 3 |
| MS4A7 | FCER1G | 0.687907 | 6 | 0 | 5 |
| MS4A7 | IRF8 | 0.682622 | 4 | 0 | 4 |
| MS4A7 | GIMAP1 | 0.681568 | 4 | 0 | 4 |
| MS4A7 | TLR4 | 0.679537 | 3 | 0 | 3 |
| MS4A7 | BTN2A2 | 0.678757 | 3 | 0 | 3 |
For details and further investigation, click here
