| Full name: SLAM family member 6 | Alias Symbol: KALI|NTBA|KALIb|Ly108|SF2000|NTB-A|CD352 | ||
| Type: protein-coding gene | Cytoband: 1q23.2-q23.3 | ||
| Entrez ID: 114836 | HGNC ID: HGNC:21392 | Ensembl Gene: ENSG00000162739 | OMIM ID: 606446 |
| Drug and gene relationship at DGIdb | |||
Expression of SLAMF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLAMF6 | 114836 | 1552497_a_at | -0.1508 | 0.8396 | |
| GSE26886 | SLAMF6 | 114836 | 1552497_a_at | -0.1452 | 0.3337 | |
| GSE45670 | SLAMF6 | 114836 | 1552497_a_at | -0.1438 | 0.4140 | |
| GSE53622 | SLAMF6 | 114836 | 17976 | 0.0010 | 0.9964 | |
| GSE53624 | SLAMF6 | 114836 | 17976 | -0.5030 | 0.0029 | |
| GSE63941 | SLAMF6 | 114836 | 1552497_a_at | 0.2984 | 0.1266 | |
| GSE77861 | SLAMF6 | 114836 | 1552497_a_at | -0.0551 | 0.8119 | |
| GSE97050 | SLAMF6 | 114836 | A_24_P45451 | 1.4419 | 0.1623 | |
| SRP007169 | SLAMF6 | 114836 | RNAseq | 0.4982 | 0.5286 | |
| SRP064894 | SLAMF6 | 114836 | RNAseq | 0.2310 | 0.4991 | |
| SRP133303 | SLAMF6 | 114836 | RNAseq | -0.1069 | 0.5251 | |
| SRP159526 | SLAMF6 | 114836 | RNAseq | -1.1674 | 0.1461 | |
| SRP193095 | SLAMF6 | 114836 | RNAseq | -0.1027 | 0.5068 | |
| SRP219564 | SLAMF6 | 114836 | RNAseq | -0.1928 | 0.7165 | |
| TCGA | SLAMF6 | 114836 | RNAseq | -0.3150 | 0.2276 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLAMF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLAMF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLAMF6 | 114836 | 10 | 0 | 20 | |
| GSE20123 | SLAMF6 | 114836 | 10 | 0 | 20 | |
| GSE43470 | SLAMF6 | 114836 | 7 | 2 | 34 | |
| GSE46452 | SLAMF6 | 114836 | 2 | 1 | 56 | |
| GSE47630 | SLAMF6 | 114836 | 14 | 0 | 26 | |
| GSE54993 | SLAMF6 | 114836 | 0 | 5 | 65 | |
| GSE54994 | SLAMF6 | 114836 | 16 | 0 | 37 | |
| GSE60625 | SLAMF6 | 114836 | 0 | 0 | 11 | |
| GSE74703 | SLAMF6 | 114836 | 7 | 2 | 27 | |
| GSE74704 | SLAMF6 | 114836 | 4 | 0 | 16 | |
| TCGA | SLAMF6 | 114836 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 13; Total Number of normals: 361.
Somatic mutations of SLAMF6:
Generating mutation plots.
Highly correlated genes for SLAMF6:
Showing top 20/333 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLAMF6 | IRF8 | 0.818218 | 5 | 0 | 5 |
| SLAMF6 | CD53 | 0.815706 | 3 | 0 | 3 |
| SLAMF6 | CORO1A | 0.810813 | 5 | 0 | 5 |
| SLAMF6 | IKZF3 | 0.793085 | 5 | 0 | 5 |
| SLAMF6 | SNX20 | 0.784702 | 4 | 0 | 4 |
| SLAMF6 | PIK3CG | 0.781767 | 4 | 0 | 4 |
| SLAMF6 | IL10RA | 0.773464 | 4 | 0 | 4 |
| SLAMF6 | GIMAP7 | 0.768006 | 5 | 0 | 5 |
| SLAMF6 | HLA-DMA | 0.767196 | 5 | 0 | 5 |
| SLAMF6 | CD48 | 0.766925 | 5 | 0 | 4 |
| SLAMF6 | ZBTB33 | 0.765844 | 3 | 0 | 3 |
| SLAMF6 | CXCL13 | 0.761097 | 5 | 0 | 5 |
| SLAMF6 | MZB1 | 0.759284 | 3 | 0 | 3 |
| SLAMF6 | POU2AF1 | 0.755292 | 4 | 0 | 4 |
| SLAMF6 | SIT1 | 0.754231 | 4 | 0 | 4 |
| SLAMF6 | ITK | 0.753167 | 6 | 0 | 6 |
| SLAMF6 | CCR2 | 0.753138 | 4 | 0 | 4 |
| SLAMF6 | GIMAP5 | 0.743313 | 4 | 0 | 4 |
| SLAMF6 | CD52 | 0.738856 | 5 | 0 | 4 |
| SLAMF6 | PDE4B | 0.736332 | 3 | 0 | 3 |
For details and further investigation, click here
