| Full name: katanin catalytic subunit A1 like 2 | Alias Symbol: MGC33211|DKFZP667C165 | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 83473 | HGNC ID: HGNC:25387 | Ensembl Gene: ENSG00000167216 | OMIM ID: 614697 |
| Drug and gene relationship at DGIdb | |||
Expression of KATNAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KATNAL2 | 83473 | 1554234_at | 0.0569 | 0.8680 | |
| GSE26886 | KATNAL2 | 83473 | 233644_at | 0.0773 | 0.6731 | |
| GSE45670 | KATNAL2 | 83473 | 1554234_at | 0.1751 | 0.3521 | |
| GSE53622 | KATNAL2 | 83473 | 56385 | -0.3437 | 0.0000 | |
| GSE53624 | KATNAL2 | 83473 | 56385 | -0.3416 | 0.0004 | |
| GSE63941 | KATNAL2 | 83473 | 1554234_at | -0.9095 | 0.0029 | |
| GSE77861 | KATNAL2 | 83473 | 233644_at | 0.0065 | 0.9638 | |
| GSE97050 | KATNAL2 | 83473 | A_33_P3209741 | -0.1058 | 0.6146 | |
| SRP064894 | KATNAL2 | 83473 | RNAseq | 0.4161 | 0.0695 | |
| SRP133303 | KATNAL2 | 83473 | RNAseq | -0.0018 | 0.9921 | |
| SRP159526 | KATNAL2 | 83473 | RNAseq | 0.8509 | 0.0607 | |
| SRP193095 | KATNAL2 | 83473 | RNAseq | 0.2258 | 0.1877 | |
| SRP219564 | KATNAL2 | 83473 | RNAseq | -0.2142 | 0.6602 | |
| TCGA | KATNAL2 | 83473 | RNAseq | 0.0260 | 0.9266 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KATNAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KATNAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KATNAL2 | 83473 | 1 | 8 | 21 | |
| GSE20123 | KATNAL2 | 83473 | 1 | 8 | 21 | |
| GSE43470 | KATNAL2 | 83473 | 0 | 5 | 38 | |
| GSE46452 | KATNAL2 | 83473 | 1 | 26 | 32 | |
| GSE47630 | KATNAL2 | 83473 | 5 | 20 | 15 | |
| GSE54993 | KATNAL2 | 83473 | 8 | 1 | 61 | |
| GSE54994 | KATNAL2 | 83473 | 2 | 15 | 36 | |
| GSE60625 | KATNAL2 | 83473 | 0 | 4 | 7 | |
| GSE74703 | KATNAL2 | 83473 | 0 | 4 | 32 | |
| GSE74704 | KATNAL2 | 83473 | 0 | 6 | 14 | |
| TCGA | KATNAL2 | 83473 | 15 | 39 | 42 |
Total number of gains: 33; Total number of losses: 136; Total Number of normals: 319.
Somatic mutations of KATNAL2:
Generating mutation plots.
Highly correlated genes for KATNAL2:
Showing top 20/109 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KATNAL2 | CHST10 | 0.796102 | 3 | 0 | 3 |
| KATNAL2 | ACR | 0.79287 | 3 | 0 | 3 |
| KATNAL2 | MAG | 0.789876 | 3 | 0 | 3 |
| KATNAL2 | NPPA | 0.783328 | 3 | 0 | 3 |
| KATNAL2 | KRTAP3-1 | 0.781508 | 3 | 0 | 3 |
| KATNAL2 | CYP17A1 | 0.745419 | 3 | 0 | 3 |
| KATNAL2 | MYOD1 | 0.743175 | 3 | 0 | 3 |
| KATNAL2 | KRTAP6-1 | 0.740479 | 3 | 0 | 3 |
| KATNAL2 | SPTBN4 | 0.737443 | 3 | 0 | 3 |
| KATNAL2 | SETDB2 | 0.736966 | 3 | 0 | 3 |
| KATNAL2 | SRPK3 | 0.736954 | 4 | 0 | 4 |
| KATNAL2 | PRG3 | 0.727457 | 3 | 0 | 3 |
| KATNAL2 | PSPN | 0.724993 | 3 | 0 | 3 |
| KATNAL2 | GDF7 | 0.719809 | 3 | 0 | 3 |
| KATNAL2 | TDGF1 | 0.718831 | 3 | 0 | 3 |
| KATNAL2 | CALML6 | 0.717689 | 3 | 0 | 3 |
| KATNAL2 | SHISA7 | 0.715856 | 3 | 0 | 3 |
| KATNAL2 | GPSM1 | 0.71443 | 4 | 0 | 4 |
| KATNAL2 | SNED1 | 0.71273 | 3 | 0 | 3 |
| KATNAL2 | SHH | 0.704086 | 3 | 0 | 3 |
For details and further investigation, click here
