| Full name: asparaginase and isoaspartyl peptidase 1 | Alias Symbol: FLJ22316|ALP1|ALP | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 80150 | HGNC ID: HGNC:16448 | Ensembl Gene: ENSG00000162174 | OMIM ID: 609212 |
| Drug and gene relationship at DGIdb | |||
Expression of ASRGL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASRGL1 | 80150 | 218857_s_at | -0.2310 | 0.6832 | |
| GSE20347 | ASRGL1 | 80150 | 218857_s_at | 0.1751 | 0.2619 | |
| GSE23400 | ASRGL1 | 80150 | 218857_s_at | -0.0102 | 0.8445 | |
| GSE26886 | ASRGL1 | 80150 | 218857_s_at | 0.3256 | 0.2165 | |
| GSE29001 | ASRGL1 | 80150 | 218857_s_at | 0.1066 | 0.6112 | |
| GSE38129 | ASRGL1 | 80150 | 218857_s_at | 0.2268 | 0.1487 | |
| GSE45670 | ASRGL1 | 80150 | 218857_s_at | 0.0191 | 0.9551 | |
| GSE53622 | ASRGL1 | 80150 | 67553 | -0.1968 | 0.0887 | |
| GSE53624 | ASRGL1 | 80150 | 67553 | -0.1055 | 0.5179 | |
| GSE63941 | ASRGL1 | 80150 | 218857_s_at | 1.1948 | 0.1648 | |
| GSE77861 | ASRGL1 | 80150 | 218857_s_at | 0.0419 | 0.8202 | |
| GSE97050 | ASRGL1 | 80150 | A_23_P203391 | 0.0894 | 0.8049 | |
| SRP064894 | ASRGL1 | 80150 | RNAseq | 0.3670 | 0.4336 | |
| SRP133303 | ASRGL1 | 80150 | RNAseq | 0.3376 | 0.4134 | |
| SRP159526 | ASRGL1 | 80150 | RNAseq | 2.1163 | 0.0000 | |
| SRP219564 | ASRGL1 | 80150 | RNAseq | 0.4690 | 0.2717 | |
| TCGA | ASRGL1 | 80150 | RNAseq | -0.7805 | 0.0022 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ASRGL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASRGL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASRGL1 | 80150 | 6 | 5 | 19 | |
| GSE20123 | ASRGL1 | 80150 | 6 | 5 | 19 | |
| GSE43470 | ASRGL1 | 80150 | 2 | 6 | 35 | |
| GSE46452 | ASRGL1 | 80150 | 8 | 4 | 47 | |
| GSE47630 | ASRGL1 | 80150 | 3 | 7 | 30 | |
| GSE54993 | ASRGL1 | 80150 | 3 | 0 | 67 | |
| GSE54994 | ASRGL1 | 80150 | 4 | 5 | 44 | |
| GSE60625 | ASRGL1 | 80150 | 0 | 3 | 8 | |
| GSE74703 | ASRGL1 | 80150 | 2 | 3 | 31 | |
| GSE74704 | ASRGL1 | 80150 | 4 | 3 | 13 | |
| TCGA | ASRGL1 | 80150 | 15 | 10 | 71 |
Total number of gains: 53; Total number of losses: 51; Total Number of normals: 384.
Somatic mutations of ASRGL1:
Generating mutation plots.
Highly correlated genes for ASRGL1:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASRGL1 | TMEM63A | 0.786279 | 3 | 0 | 3 |
| ASRGL1 | MAG | 0.767616 | 3 | 0 | 3 |
| ASRGL1 | POLM | 0.753871 | 3 | 0 | 3 |
| ASRGL1 | SHD | 0.752633 | 3 | 0 | 3 |
| ASRGL1 | STX1B | 0.751733 | 3 | 0 | 3 |
| ASRGL1 | GPD1 | 0.734017 | 3 | 0 | 3 |
| ASRGL1 | SLC39A5 | 0.73382 | 3 | 0 | 3 |
| ASRGL1 | TSPAN11 | 0.729701 | 3 | 0 | 3 |
| ASRGL1 | SMOC1 | 0.708229 | 3 | 0 | 3 |
| ASRGL1 | LRRN4 | 0.703206 | 3 | 0 | 3 |
| ASRGL1 | KCNH3 | 0.698793 | 3 | 0 | 3 |
| ASRGL1 | PRODH2 | 0.697397 | 3 | 0 | 3 |
| ASRGL1 | RFPL1S | 0.695603 | 3 | 0 | 3 |
| ASRGL1 | ZNF843 | 0.690635 | 3 | 0 | 3 |
| ASRGL1 | SPACA1 | 0.687597 | 3 | 0 | 3 |
| ASRGL1 | ALPL | 0.687286 | 3 | 0 | 3 |
| ASRGL1 | ABCA4 | 0.684285 | 3 | 0 | 3 |
| ASRGL1 | GNB3 | 0.678786 | 3 | 0 | 3 |
| ASRGL1 | CDH22 | 0.676442 | 4 | 0 | 3 |
| ASRGL1 | FTHL17 | 0.672575 | 3 | 0 | 3 |
For details and further investigation, click here
