| Full name: membrane bound O-acyltransferase domain containing 1 | Alias Symbol: MGC44669|dJ434O11.1|LPEAT1 | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 154141 | HGNC ID: HGNC:21579 | Ensembl Gene: ENSG00000172197 | OMIM ID: 611732 |
| Drug and gene relationship at DGIdb | |||
Expression of MBOAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MBOAT1 | 154141 | 227379_at | 0.0669 | 0.9684 | |
| GSE26886 | MBOAT1 | 154141 | 227379_at | -0.8997 | 0.0233 | |
| GSE45670 | MBOAT1 | 154141 | 227379_at | -0.3035 | 0.2356 | |
| GSE63941 | MBOAT1 | 154141 | 227379_at | 1.9274 | 0.0217 | |
| GSE77861 | MBOAT1 | 154141 | 227379_at | -0.0298 | 0.9599 | |
| GSE97050 | MBOAT1 | 154141 | A_23_P408996 | -0.2566 | 0.3624 | |
| SRP007169 | MBOAT1 | 154141 | RNAseq | 0.3883 | 0.3570 | |
| SRP064894 | MBOAT1 | 154141 | RNAseq | -0.4364 | 0.0614 | |
| SRP133303 | MBOAT1 | 154141 | RNAseq | -0.0045 | 0.9911 | |
| SRP159526 | MBOAT1 | 154141 | RNAseq | -0.0499 | 0.9138 | |
| SRP193095 | MBOAT1 | 154141 | RNAseq | -0.5484 | 0.0105 | |
| SRP219564 | MBOAT1 | 154141 | RNAseq | 0.0376 | 0.9127 | |
| TCGA | MBOAT1 | 154141 | RNAseq | -0.2807 | 0.0046 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MBOAT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MBOAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MBOAT1 | 154141 | 4 | 4 | 22 | |
| GSE20123 | MBOAT1 | 154141 | 4 | 4 | 22 | |
| GSE43470 | MBOAT1 | 154141 | 10 | 0 | 33 | |
| GSE46452 | MBOAT1 | 154141 | 3 | 9 | 47 | |
| GSE47630 | MBOAT1 | 154141 | 10 | 4 | 26 | |
| GSE54993 | MBOAT1 | 154141 | 1 | 1 | 68 | |
| GSE54994 | MBOAT1 | 154141 | 12 | 3 | 38 | |
| GSE60625 | MBOAT1 | 154141 | 0 | 1 | 10 | |
| GSE74703 | MBOAT1 | 154141 | 9 | 0 | 27 | |
| GSE74704 | MBOAT1 | 154141 | 1 | 1 | 18 | |
| TCGA | MBOAT1 | 154141 | 18 | 23 | 55 |
Total number of gains: 72; Total number of losses: 50; Total Number of normals: 366.
Somatic mutations of MBOAT1:
Generating mutation plots.
Highly correlated genes for MBOAT1:
Showing top 20/293 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MBOAT1 | TBCC | 0.790243 | 3 | 0 | 3 |
| MBOAT1 | YIPF3 | 0.77332 | 3 | 0 | 3 |
| MBOAT1 | SLC25A10 | 0.7724 | 3 | 0 | 3 |
| MBOAT1 | PUS7L | 0.768273 | 3 | 0 | 3 |
| MBOAT1 | TRAPPC2 | 0.767527 | 3 | 0 | 3 |
| MBOAT1 | COIL | 0.766022 | 3 | 0 | 3 |
| MBOAT1 | GPANK1 | 0.765775 | 3 | 0 | 3 |
| MBOAT1 | KDM6A | 0.754465 | 3 | 0 | 3 |
| MBOAT1 | ZNF506 | 0.745715 | 3 | 0 | 3 |
| MBOAT1 | ASPSCR1 | 0.73917 | 3 | 0 | 3 |
| MBOAT1 | ERCC6 | 0.728965 | 3 | 0 | 3 |
| MBOAT1 | PPP2R1A | 0.72859 | 3 | 0 | 3 |
| MBOAT1 | ZNF398 | 0.727514 | 3 | 0 | 3 |
| MBOAT1 | SYT17 | 0.724948 | 3 | 0 | 3 |
| MBOAT1 | BLOC1S1 | 0.723016 | 3 | 0 | 3 |
| MBOAT1 | PTGES3 | 0.717257 | 3 | 0 | 3 |
| MBOAT1 | ZNF740 | 0.715868 | 3 | 0 | 3 |
| MBOAT1 | ZNF416 | 0.714418 | 3 | 0 | 3 |
| MBOAT1 | TRAPPC8 | 0.710186 | 3 | 0 | 3 |
| MBOAT1 | ZNF184 | 0.705801 | 3 | 0 | 3 |
For details and further investigation, click here
