| Full name: coilin | Alias Symbol: CLN80|p80-coilin | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 8161 | HGNC ID: HGNC:2184 | Ensembl Gene: ENSG00000121058 | OMIM ID: 600272 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COIL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COIL | 8161 | 203654_s_at | 0.0534 | 0.8802 | |
| GSE20347 | COIL | 8161 | 203654_s_at | 0.2041 | 0.1339 | |
| GSE23400 | COIL | 8161 | 203654_s_at | 0.2542 | 0.0002 | |
| GSE26886 | COIL | 8161 | 203654_s_at | -0.3685 | 0.1954 | |
| GSE29001 | COIL | 8161 | 203654_s_at | 0.3406 | 0.1102 | |
| GSE38129 | COIL | 8161 | 203654_s_at | 0.3412 | 0.0040 | |
| GSE45670 | COIL | 8161 | 203654_s_at | 0.0954 | 0.4462 | |
| GSE53622 | COIL | 8161 | 76950 | 0.0657 | 0.2439 | |
| GSE53624 | COIL | 8161 | 76950 | 0.1191 | 0.0214 | |
| GSE63941 | COIL | 8161 | 203654_s_at | 0.1521 | 0.6567 | |
| GSE77861 | COIL | 8161 | 203654_s_at | 0.1388 | 0.6575 | |
| GSE97050 | COIL | 8161 | A_33_P3315410 | 0.0120 | 0.9650 | |
| SRP007169 | COIL | 8161 | RNAseq | 0.6491 | 0.1635 | |
| SRP008496 | COIL | 8161 | RNAseq | 0.6416 | 0.0471 | |
| SRP064894 | COIL | 8161 | RNAseq | 0.0703 | 0.5989 | |
| SRP133303 | COIL | 8161 | RNAseq | 0.4163 | 0.0488 | |
| SRP159526 | COIL | 8161 | RNAseq | 0.2294 | 0.1703 | |
| SRP193095 | COIL | 8161 | RNAseq | -0.1177 | 0.1329 | |
| SRP219564 | COIL | 8161 | RNAseq | 0.3558 | 0.3847 | |
| TCGA | COIL | 8161 | RNAseq | 0.1607 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COIL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COIL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COIL | 8161 | 5 | 1 | 24 | |
| GSE20123 | COIL | 8161 | 5 | 1 | 24 | |
| GSE43470 | COIL | 8161 | 3 | 1 | 39 | |
| GSE46452 | COIL | 8161 | 32 | 0 | 27 | |
| GSE47630 | COIL | 8161 | 7 | 1 | 32 | |
| GSE54993 | COIL | 8161 | 2 | 4 | 64 | |
| GSE54994 | COIL | 8161 | 8 | 5 | 40 | |
| GSE60625 | COIL | 8161 | 4 | 0 | 7 | |
| GSE74703 | COIL | 8161 | 3 | 1 | 32 | |
| GSE74704 | COIL | 8161 | 4 | 1 | 15 | |
| TCGA | COIL | 8161 | 27 | 6 | 63 |
Total number of gains: 100; Total number of losses: 21; Total Number of normals: 367.
Somatic mutations of COIL:
Generating mutation plots.
Highly correlated genes for COIL:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COIL | ZNF564 | 0.823792 | 3 | 0 | 3 |
| COIL | ZNF700 | 0.770843 | 3 | 0 | 3 |
| COIL | MBOAT1 | 0.766022 | 3 | 0 | 3 |
| COIL | LRIG3 | 0.765186 | 3 | 0 | 3 |
| COIL | RWDD4 | 0.764276 | 3 | 0 | 3 |
| COIL | METTL14 | 0.755962 | 3 | 0 | 3 |
| COIL | NAA30 | 0.743412 | 3 | 0 | 3 |
| COIL | TET2 | 0.738851 | 4 | 0 | 3 |
| COIL | NCOA2 | 0.737729 | 3 | 0 | 3 |
| COIL | RCOR3 | 0.735582 | 3 | 0 | 3 |
| COIL | PAN3 | 0.729535 | 3 | 0 | 3 |
| COIL | MRPS18A | 0.72393 | 3 | 0 | 3 |
| COIL | LETMD1 | 0.717691 | 3 | 0 | 3 |
| COIL | ELF2 | 0.713536 | 3 | 0 | 3 |
| COIL | DZIP3 | 0.712557 | 3 | 0 | 3 |
| COIL | MRPL10 | 0.711764 | 4 | 0 | 4 |
| COIL | AGTPBP1 | 0.710492 | 3 | 0 | 3 |
| COIL | HCCS | 0.70997 | 3 | 0 | 3 |
| COIL | ANKRD28 | 0.708832 | 3 | 0 | 3 |
| COIL | WIPI2 | 0.707184 | 3 | 0 | 3 |
For details and further investigation, click here
