SYT17

 

Full name: synaptotagmin 17 Alias Symbol: 
Type: protein-coding gene Cytoband: 16p12.3
Entrez ID: 51760 HGNC ID: HGNC:24119 Ensembl Gene: ENSG00000103528 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SYT17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SYT17 51760 205613_at 0.1863 0.8519
GSE20347 SYT17 51760 205613_at 0.3796 0.1017
GSE23400 SYT17 51760 205613_at 0.0237 0.7733
GSE26886 SYT17 51760 205613_at 0.4449 0.1853
GSE29001 SYT17 51760 205613_at -0.2012 0.6520
GSE38129 SYT17 51760 205613_at 0.3121 0.1347
GSE45670 SYT17 51760 205613_at 0.1052 0.7616
GSE53622 SYT17 51760 19346 0.2247 0.2007
GSE53624 SYT17 51760 19346 -0.2806 0.0348
GSE63941 SYT17 51760 205613_at 2.2648 0.0075
GSE77861 SYT17 51760 205613_at 0.0526 0.8557
GSE97050 SYT17 51760 A_23_P163697 0.2783 0.5294
SRP007169 SYT17 51760 RNAseq 0.4779 0.3420
SRP064894 SYT17 51760 RNAseq -0.3861 0.2750
SRP133303 SYT17 51760 RNAseq 0.8132 0.0406
SRP159526 SYT17 51760 RNAseq 0.4806 0.4044
SRP193095 SYT17 51760 RNAseq 0.3936 0.0580
SRP219564 SYT17 51760 RNAseq 0.8270 0.0364
TCGA SYT17 51760 RNAseq -0.1748 0.3965

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by SYT17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SYT17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SYT17 51760 5 3 22
GSE20123 SYT17 51760 5 2 23
GSE43470 SYT17 51760 3 3 37
GSE46452 SYT17 51760 38 1 20
GSE47630 SYT17 51760 11 6 23
GSE54993 SYT17 51760 3 5 62
GSE54994 SYT17 51760 3 10 40
GSE60625 SYT17 51760 4 0 7
GSE74703 SYT17 51760 3 2 31
GSE74704 SYT17 51760 2 1 17
TCGA SYT17 51760 20 12 64

Total number of gains: 97; Total number of losses: 45; Total Number of normals: 346.  


 

Somatic mutations of SYT17:

 

Generating mutation plots.

 

Highly correlated genes for SYT17:

 

Showing top 20/190 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SYT17ZKSCAN50.763698303
SYT17PTGES30.748497303
SYT17MBOAT10.724948303
SYT17ARID20.721776303
SYT17ACTR60.721374303
SYT17MRPL380.71678303
SYT17ELF20.71487303
SYT17PMF10.712244303
SYT17RNF1380.710105303
SYT17ITPRIPL20.708301505
SYT17PPP1CC0.701397303
SYT17VPS520.699361303
SYT17PRKCH0.695925303
SYT17SRP680.69585303
SYT17ZNF7650.692094303
SYT17MAGEA60.691803303
SYT17COMMD70.68696303
SYT17SYNGR20.686626303
SYT17CHCHD50.683025303
SYT17LSM40.679492303

For details and further investigation, click here