| Full name: pseudouridine synthase 7 like | Alias Symbol: DKFZP434G1415 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 83448 | HGNC ID: HGNC:25276 | Ensembl Gene: ENSG00000129317 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PUS7L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PUS7L | 83448 | 221025_x_at | 0.1112 | 0.8573 | |
| GSE20347 | PUS7L | 83448 | 221025_x_at | 0.1598 | 0.1027 | |
| GSE23400 | PUS7L | 83448 | 221025_x_at | 0.0055 | 0.8990 | |
| GSE26886 | PUS7L | 83448 | 221025_x_at | -0.9230 | 0.0000 | |
| GSE29001 | PUS7L | 83448 | 221025_x_at | 0.1656 | 0.5030 | |
| GSE38129 | PUS7L | 83448 | 221025_x_at | 0.1879 | 0.0638 | |
| GSE45670 | PUS7L | 83448 | 221025_x_at | 0.3135 | 0.0080 | |
| GSE53622 | PUS7L | 83448 | 42810 | -0.1486 | 0.0476 | |
| GSE53624 | PUS7L | 83448 | 42810 | -0.0724 | 0.4490 | |
| GSE63941 | PUS7L | 83448 | 221025_x_at | -0.3006 | 0.4942 | |
| GSE77861 | PUS7L | 83448 | 221025_x_at | 0.0626 | 0.7644 | |
| GSE97050 | PUS7L | 83448 | A_24_P167496 | 0.0370 | 0.8863 | |
| SRP007169 | PUS7L | 83448 | RNAseq | 0.7145 | 0.0964 | |
| SRP008496 | PUS7L | 83448 | RNAseq | 0.3673 | 0.1828 | |
| SRP064894 | PUS7L | 83448 | RNAseq | -0.2088 | 0.3346 | |
| SRP133303 | PUS7L | 83448 | RNAseq | 0.3001 | 0.0393 | |
| SRP159526 | PUS7L | 83448 | RNAseq | -0.3123 | 0.0923 | |
| SRP193095 | PUS7L | 83448 | RNAseq | -0.0540 | 0.4803 | |
| SRP219564 | PUS7L | 83448 | RNAseq | -0.2738 | 0.4740 | |
| TCGA | PUS7L | 83448 | RNAseq | -0.0282 | 0.6710 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PUS7L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PUS7L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PUS7L | 83448 | 4 | 1 | 25 | |
| GSE20123 | PUS7L | 83448 | 4 | 1 | 25 | |
| GSE43470 | PUS7L | 83448 | 3 | 3 | 37 | |
| GSE46452 | PUS7L | 83448 | 8 | 1 | 50 | |
| GSE47630 | PUS7L | 83448 | 11 | 2 | 27 | |
| GSE54993 | PUS7L | 83448 | 0 | 6 | 64 | |
| GSE54994 | PUS7L | 83448 | 7 | 1 | 45 | |
| GSE60625 | PUS7L | 83448 | 0 | 0 | 11 | |
| GSE74703 | PUS7L | 83448 | 3 | 2 | 31 | |
| GSE74704 | PUS7L | 83448 | 2 | 1 | 17 | |
| TCGA | PUS7L | 83448 | 16 | 13 | 67 |
Total number of gains: 58; Total number of losses: 31; Total Number of normals: 399.
Somatic mutations of PUS7L:
Generating mutation plots.
Highly correlated genes for PUS7L:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PUS7L | ZNF416 | 0.807404 | 3 | 0 | 3 |
| PUS7L | ITPRIPL2 | 0.789357 | 3 | 0 | 3 |
| PUS7L | MKRN1 | 0.785971 | 3 | 0 | 3 |
| PUS7L | C1orf174 | 0.782124 | 3 | 0 | 3 |
| PUS7L | ZNF304 | 0.778175 | 3 | 0 | 3 |
| PUS7L | ZNF641 | 0.778094 | 3 | 0 | 3 |
| PUS7L | ZNF564 | 0.773758 | 3 | 0 | 3 |
| PUS7L | CNOT10 | 0.771373 | 3 | 0 | 3 |
| PUS7L | EXOC4 | 0.76935 | 3 | 0 | 3 |
| PUS7L | MBOAT1 | 0.768273 | 3 | 0 | 3 |
| PUS7L | C2CD2 | 0.764097 | 3 | 0 | 3 |
| PUS7L | RNF149 | 0.761025 | 3 | 0 | 3 |
| PUS7L | NIPSNAP3A | 0.760166 | 3 | 0 | 3 |
| PUS7L | GNPTAB | 0.755795 | 3 | 0 | 3 |
| PUS7L | B3GNT2 | 0.755374 | 3 | 0 | 3 |
| PUS7L | MRPL35 | 0.754137 | 3 | 0 | 3 |
| PUS7L | RCAN3 | 0.749893 | 3 | 0 | 3 |
| PUS7L | UBE2H | 0.748978 | 3 | 0 | 3 |
| PUS7L | ZNF436 | 0.748837 | 3 | 0 | 3 |
| PUS7L | C3orf38 | 0.746233 | 3 | 0 | 3 |
For details and further investigation, click here
