| Full name: zinc finger protein 740 | Alias Symbol: Zfp740 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 283337 | HGNC ID: HGNC:27465 | Ensembl Gene: ENSG00000139651 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF740:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF740 | 283337 | 227331_at | 0.2491 | 0.5204 | |
| GSE26886 | ZNF740 | 283337 | 227331_at | -0.3893 | 0.0081 | |
| GSE45670 | ZNF740 | 283337 | 227331_at | -0.0911 | 0.3636 | |
| GSE53622 | ZNF740 | 283337 | 20969 | 0.1627 | 0.0885 | |
| GSE53624 | ZNF740 | 283337 | 20969 | 0.4149 | 0.0000 | |
| GSE63941 | ZNF740 | 283337 | 227331_at | 0.6130 | 0.0313 | |
| GSE77861 | ZNF740 | 283337 | 227331_at | 0.0568 | 0.7530 | |
| GSE97050 | ZNF740 | 283337 | A_33_P3334108 | -0.0090 | 0.9769 | |
| SRP007169 | ZNF740 | 283337 | RNAseq | 1.0975 | 0.0033 | |
| SRP008496 | ZNF740 | 283337 | RNAseq | 0.6624 | 0.0290 | |
| SRP064894 | ZNF740 | 283337 | RNAseq | 0.0271 | 0.8175 | |
| SRP133303 | ZNF740 | 283337 | RNAseq | -0.0783 | 0.4997 | |
| SRP159526 | ZNF740 | 283337 | RNAseq | 0.0639 | 0.8002 | |
| SRP193095 | ZNF740 | 283337 | RNAseq | -0.0247 | 0.7594 | |
| SRP219564 | ZNF740 | 283337 | RNAseq | 0.0421 | 0.8593 | |
| TCGA | ZNF740 | 283337 | RNAseq | -0.0215 | 0.7083 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF740 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF740:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF740 | 283337 | 8 | 1 | 21 | |
| GSE20123 | ZNF740 | 283337 | 8 | 1 | 21 | |
| GSE43470 | ZNF740 | 283337 | 3 | 0 | 40 | |
| GSE46452 | ZNF740 | 283337 | 7 | 1 | 51 | |
| GSE47630 | ZNF740 | 283337 | 10 | 2 | 28 | |
| GSE54993 | ZNF740 | 283337 | 0 | 5 | 65 | |
| GSE54994 | ZNF740 | 283337 | 4 | 1 | 48 | |
| GSE60625 | ZNF740 | 283337 | 0 | 0 | 11 | |
| GSE74703 | ZNF740 | 283337 | 3 | 0 | 33 | |
| GSE74704 | ZNF740 | 283337 | 5 | 1 | 14 | |
| TCGA | ZNF740 | 283337 | 13 | 11 | 72 |
Total number of gains: 61; Total number of losses: 23; Total Number of normals: 404.
Somatic mutations of ZNF740:
Generating mutation plots.
Highly correlated genes for ZNF740:
Showing top 20/419 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF740 | KDM4A | 0.811678 | 3 | 0 | 3 |
| ZNF740 | AKT1S1 | 0.790478 | 3 | 0 | 3 |
| ZNF740 | UBR7 | 0.772379 | 3 | 0 | 3 |
| ZNF740 | RBM8A | 0.769206 | 3 | 0 | 3 |
| ZNF740 | C1orf174 | 0.76876 | 3 | 0 | 3 |
| ZNF740 | VDAC2 | 0.758468 | 3 | 0 | 3 |
| ZNF740 | IKZF5 | 0.753986 | 3 | 0 | 3 |
| ZNF740 | LSM14A | 0.74961 | 3 | 0 | 3 |
| ZNF740 | ZNF3 | 0.742929 | 3 | 0 | 3 |
| ZNF740 | DTX4 | 0.737925 | 3 | 0 | 3 |
| ZNF740 | POLR3C | 0.731385 | 3 | 0 | 3 |
| ZNF740 | NDUFV1 | 0.73014 | 4 | 0 | 4 |
| ZNF740 | C5orf51 | 0.730117 | 3 | 0 | 3 |
| ZNF740 | FARSA | 0.72545 | 4 | 0 | 4 |
| ZNF740 | ZCCHC8 | 0.723384 | 3 | 0 | 3 |
| ZNF740 | XRCC6 | 0.723233 | 3 | 0 | 3 |
| ZNF740 | ZFYVE27 | 0.723078 | 3 | 0 | 3 |
| ZNF740 | CDK10 | 0.720873 | 3 | 0 | 3 |
| ZNF740 | SURF1 | 0.718919 | 3 | 0 | 3 |
| ZNF740 | ATG4C | 0.718364 | 4 | 0 | 3 |
For details and further investigation, click here
