| Full name: MAM domain containing glycosylphosphatidylinositol anchor 1 | Alias Symbol: GPIM|MAMDC3 | ||
| Type: protein-coding gene | Cytoband: 6p21.2 | ||
| Entrez ID: 266727 | HGNC ID: HGNC:19267 | Ensembl Gene: ENSG00000112139 | OMIM ID: 609626 |
| Drug and gene relationship at DGIdb | |||
Expression of MDGA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MDGA1 | 266727 | 232237_at | 0.1324 | 0.6876 | |
| GSE26886 | MDGA1 | 266727 | 232237_at | 0.2322 | 0.1086 | |
| GSE45670 | MDGA1 | 266727 | 232237_at | 0.2403 | 0.1604 | |
| GSE53622 | MDGA1 | 266727 | 16432 | 0.1469 | 0.6085 | |
| GSE53624 | MDGA1 | 266727 | 16432 | 0.5996 | 0.0003 | |
| GSE63941 | MDGA1 | 266727 | 232237_at | -0.5680 | 0.0058 | |
| GSE77861 | MDGA1 | 266727 | 232237_at | 0.1969 | 0.5027 | |
| GSE97050 | MDGA1 | 266727 | A_33_P3421867 | -0.0099 | 0.9714 | |
| SRP007169 | MDGA1 | 266727 | RNAseq | 2.0750 | 0.0199 | |
| SRP064894 | MDGA1 | 266727 | RNAseq | 0.4617 | 0.2494 | |
| SRP133303 | MDGA1 | 266727 | RNAseq | 0.6435 | 0.0210 | |
| SRP159526 | MDGA1 | 266727 | RNAseq | 1.6410 | 0.0158 | |
| SRP193095 | MDGA1 | 266727 | RNAseq | 1.6678 | 0.0000 | |
| SRP219564 | MDGA1 | 266727 | RNAseq | 0.5334 | 0.3664 | |
| TCGA | MDGA1 | 266727 | RNAseq | 0.0480 | 0.8189 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MDGA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MDGA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MDGA1 | 266727 | 6 | 0 | 24 | |
| GSE20123 | MDGA1 | 266727 | 6 | 0 | 24 | |
| GSE43470 | MDGA1 | 266727 | 6 | 1 | 36 | |
| GSE46452 | MDGA1 | 266727 | 2 | 9 | 48 | |
| GSE47630 | MDGA1 | 266727 | 8 | 4 | 28 | |
| GSE54993 | MDGA1 | 266727 | 3 | 1 | 66 | |
| GSE54994 | MDGA1 | 266727 | 11 | 4 | 38 | |
| GSE60625 | MDGA1 | 266727 | 0 | 1 | 10 | |
| GSE74703 | MDGA1 | 266727 | 6 | 0 | 30 | |
| GSE74704 | MDGA1 | 266727 | 3 | 0 | 17 | |
| TCGA | MDGA1 | 266727 | 16 | 14 | 66 |
Total number of gains: 67; Total number of losses: 34; Total Number of normals: 387.
Somatic mutations of MDGA1:
Generating mutation plots.
Highly correlated genes for MDGA1:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MDGA1 | RING1 | 0.729314 | 3 | 0 | 3 |
| MDGA1 | TMEM155 | 0.708956 | 3 | 0 | 3 |
| MDGA1 | SLC10A3 | 0.700842 | 3 | 0 | 3 |
| MDGA1 | EVL | 0.69957 | 3 | 0 | 3 |
| MDGA1 | SERPING1 | 0.67195 | 3 | 0 | 3 |
| MDGA1 | GAS6 | 0.670911 | 4 | 0 | 3 |
| MDGA1 | EDNRB | 0.6693 | 3 | 0 | 3 |
| MDGA1 | C1orf35 | 0.662886 | 3 | 0 | 3 |
| MDGA1 | CCDC80 | 0.659467 | 3 | 0 | 3 |
| MDGA1 | RCN1 | 0.658698 | 4 | 0 | 3 |
| MDGA1 | VEGFB | 0.654165 | 3 | 0 | 3 |
| MDGA1 | HSD11B1 | 0.653925 | 3 | 0 | 3 |
| MDGA1 | GORASP2 | 0.649689 | 4 | 0 | 3 |
| MDGA1 | CCNE1 | 0.64831 | 3 | 0 | 3 |
| MDGA1 | PLEKHA4 | 0.645355 | 4 | 0 | 4 |
| MDGA1 | HABP4 | 0.645216 | 3 | 0 | 3 |
| MDGA1 | CCDC102B | 0.638757 | 3 | 0 | 3 |
| MDGA1 | FAM160B1 | 0.634761 | 3 | 0 | 3 |
| MDGA1 | GNG11 | 0.632001 | 3 | 0 | 3 |
| MDGA1 | FAM160A2 | 0.630387 | 3 | 0 | 3 |
For details and further investigation, click here
