| Full name: growth arrest specific 6 | Alias Symbol: AXSF|FLJ34709|DKFZp666G247 | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 2621 | HGNC ID: HGNC:4168 | Ensembl Gene: ENSG00000183087 | OMIM ID: 600441 |
| Drug and gene relationship at DGIdb | |||
Expression of GAS6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GAS6 | 2621 | 1598_g_at | -0.1136 | 0.9460 | |
| GSE20347 | GAS6 | 2621 | 1598_g_at | 0.4005 | 0.2059 | |
| GSE23400 | GAS6 | 2621 | 1598_g_at | -0.1842 | 0.0487 | |
| GSE26886 | GAS6 | 2621 | 1598_g_at | 0.3572 | 0.2222 | |
| GSE29001 | GAS6 | 2621 | 1598_g_at | -0.1257 | 0.6378 | |
| GSE38129 | GAS6 | 2621 | 1598_g_at | -0.0668 | 0.8297 | |
| GSE45670 | GAS6 | 2621 | 1598_g_at | -0.8008 | 0.0001 | |
| GSE53622 | GAS6 | 2621 | 94662 | -0.3596 | 0.0050 | |
| GSE53624 | GAS6 | 2621 | 94662 | -0.3069 | 0.0047 | |
| GSE63941 | GAS6 | 2621 | 1598_g_at | -2.4803 | 0.0016 | |
| GSE77861 | GAS6 | 2621 | 1598_g_at | 0.0699 | 0.8002 | |
| GSE97050 | GAS6 | 2621 | A_23_P146922 | -0.2232 | 0.4077 | |
| SRP007169 | GAS6 | 2621 | RNAseq | -0.3871 | 0.4310 | |
| SRP008496 | GAS6 | 2621 | RNAseq | 0.0423 | 0.9063 | |
| SRP064894 | GAS6 | 2621 | RNAseq | -0.1058 | 0.7589 | |
| SRP133303 | GAS6 | 2621 | RNAseq | -0.7378 | 0.0436 | |
| SRP159526 | GAS6 | 2621 | RNAseq | -0.3164 | 0.1106 | |
| SRP193095 | GAS6 | 2621 | RNAseq | -0.0138 | 0.9376 | |
| TCGA | GAS6 | 2621 | RNAseq | -0.3007 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GAS6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GAS6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GAS6 | 2621 | 6 | 12 | 12 | |
| GSE20123 | GAS6 | 2621 | 6 | 11 | 13 | |
| GSE43470 | GAS6 | 2621 | 4 | 13 | 26 | |
| GSE46452 | GAS6 | 2621 | 3 | 31 | 25 | |
| GSE47630 | GAS6 | 2621 | 3 | 26 | 11 | |
| GSE54993 | GAS6 | 2621 | 12 | 3 | 55 | |
| GSE54994 | GAS6 | 2621 | 9 | 10 | 34 | |
| GSE60625 | GAS6 | 2621 | 0 | 3 | 8 | |
| GSE74703 | GAS6 | 2621 | 3 | 10 | 23 | |
| GSE74704 | GAS6 | 2621 | 4 | 9 | 7 | |
| TCGA | GAS6 | 2621 | 19 | 32 | 45 |
Total number of gains: 69; Total number of losses: 160; Total Number of normals: 259.
Somatic mutations of GAS6:
Generating mutation plots.
Highly correlated genes for GAS6:
Showing top 20/731 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GAS6 | ACSF2 | 0.765082 | 3 | 0 | 3 |
| GAS6 | DPP7 | 0.760611 | 3 | 0 | 3 |
| GAS6 | FIBIN | 0.755168 | 3 | 0 | 3 |
| GAS6 | SNX27 | 0.754297 | 3 | 0 | 3 |
| GAS6 | TMEM181 | 0.747842 | 3 | 0 | 3 |
| GAS6 | GLIS3 | 0.739254 | 3 | 0 | 3 |
| GAS6 | C11orf68 | 0.737354 | 3 | 0 | 3 |
| GAS6 | SHISA5 | 0.736328 | 3 | 0 | 3 |
| GAS6 | SLC30A4 | 0.733748 | 3 | 0 | 3 |
| GAS6 | ING1 | 0.733729 | 4 | 0 | 4 |
| GAS6 | TRPV2 | 0.732305 | 4 | 0 | 4 |
| GAS6 | NEU3 | 0.731816 | 3 | 0 | 3 |
| GAS6 | DHRSX | 0.72774 | 3 | 0 | 3 |
| GAS6 | CHIC1 | 0.722817 | 3 | 0 | 3 |
| GAS6 | CHAMP1 | 0.720727 | 3 | 0 | 3 |
| GAS6 | RAB11FIP5 | 0.718684 | 4 | 0 | 4 |
| GAS6 | TRIM56 | 0.718329 | 3 | 0 | 3 |
| GAS6 | TMOD2 | 0.715098 | 4 | 0 | 4 |
| GAS6 | OAF | 0.712494 | 3 | 0 | 3 |
| GAS6 | FAM161B | 0.711555 | 3 | 0 | 3 |
For details and further investigation, click here
