| Full name: Enah/Vasp-like | Alias Symbol: RNB6 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 51466 | HGNC ID: HGNC:20234 | Ensembl Gene: ENSG00000196405 | OMIM ID: 616912 |
| Drug and gene relationship at DGIdb | |||
Expression of EVL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EVL | 51466 | 217838_s_at | 0.4843 | 0.4460 | |
| GSE20347 | EVL | 51466 | 217838_s_at | 0.3495 | 0.0310 | |
| GSE23400 | EVL | 51466 | 217838_s_at | 0.5135 | 0.0000 | |
| GSE26886 | EVL | 51466 | 217838_s_at | 0.7092 | 0.0540 | |
| GSE29001 | EVL | 51466 | 217838_s_at | 0.3702 | 0.1410 | |
| GSE38129 | EVL | 51466 | 217838_s_at | 0.2484 | 0.2314 | |
| GSE45670 | EVL | 51466 | 217838_s_at | 0.1077 | 0.5639 | |
| GSE63941 | EVL | 51466 | 217838_s_at | -1.1136 | 0.0809 | |
| GSE77861 | EVL | 51466 | 217838_s_at | 0.5043 | 0.2261 | |
| GSE97050 | EVL | 51466 | A_23_P140427 | 0.3904 | 0.1894 | |
| SRP007169 | EVL | 51466 | RNAseq | 2.2508 | 0.0063 | |
| SRP008496 | EVL | 51466 | RNAseq | 2.7052 | 0.0001 | |
| SRP064894 | EVL | 51466 | RNAseq | 0.7460 | 0.0008 | |
| SRP133303 | EVL | 51466 | RNAseq | 0.0186 | 0.9228 | |
| SRP159526 | EVL | 51466 | RNAseq | 0.0453 | 0.8999 | |
| SRP193095 | EVL | 51466 | RNAseq | 0.0952 | 0.6038 | |
| SRP219564 | EVL | 51466 | RNAseq | 0.1861 | 0.5744 | |
| TCGA | EVL | 51466 | RNAseq | -0.0325 | 0.5872 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by EVL expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EVL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EVL | 51466 | 9 | 5 | 16 | |
| GSE20123 | EVL | 51466 | 9 | 4 | 17 | |
| GSE43470 | EVL | 51466 | 7 | 4 | 32 | |
| GSE46452 | EVL | 51466 | 17 | 3 | 39 | |
| GSE47630 | EVL | 51466 | 11 | 8 | 21 | |
| GSE54993 | EVL | 51466 | 3 | 8 | 59 | |
| GSE54994 | EVL | 51466 | 21 | 4 | 28 | |
| GSE60625 | EVL | 51466 | 0 | 2 | 9 | |
| GSE74703 | EVL | 51466 | 6 | 3 | 27 | |
| GSE74704 | EVL | 51466 | 5 | 3 | 12 | |
| TCGA | EVL | 51466 | 31 | 18 | 47 |
Total number of gains: 119; Total number of losses: 62; Total Number of normals: 307.
Somatic mutations of EVL:
Generating mutation plots.
Highly correlated genes for EVL:
Showing top 20/769 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EVL | AP3B2 | 0.836188 | 3 | 0 | 3 |
| EVL | OAF | 0.796009 | 3 | 0 | 3 |
| EVL | ZDHHC14 | 0.782561 | 3 | 0 | 3 |
| EVL | IL6R | 0.770207 | 3 | 0 | 3 |
| EVL | SLC41A2 | 0.768585 | 3 | 0 | 3 |
| EVL | SNAPC4 | 0.763765 | 3 | 0 | 3 |
| EVL | SRSF1 | 0.758161 | 3 | 0 | 3 |
| EVL | CRTC2 | 0.752593 | 3 | 0 | 3 |
| EVL | PMS1 | 0.751386 | 3 | 0 | 3 |
| EVL | ACAP1 | 0.751027 | 3 | 0 | 3 |
| EVL | CLPTM1L | 0.747139 | 3 | 0 | 3 |
| EVL | THEM4 | 0.739539 | 3 | 0 | 3 |
| EVL | DUSP23 | 0.739148 | 3 | 0 | 3 |
| EVL | ZNF280C | 0.738858 | 3 | 0 | 3 |
| EVL | TP53I13 | 0.734593 | 4 | 0 | 3 |
| EVL | PDGFB | 0.729013 | 3 | 0 | 3 |
| EVL | CCDC97 | 0.725218 | 3 | 0 | 3 |
| EVL | TMTC4 | 0.71806 | 4 | 0 | 4 |
| EVL | RICTOR | 0.71791 | 3 | 0 | 3 |
| EVL | KLHL5 | 0.717173 | 3 | 0 | 3 |
For details and further investigation, click here
