| Full name: reticulocalbin 1 | Alias Symbol: Rcal|PIG20|FLJ37041 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 5954 | HGNC ID: HGNC:9934 | Ensembl Gene: ENSG00000049449 | OMIM ID: 602735 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RCN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCN1 | 5954 | 201063_at | 0.6807 | 0.2589 | |
| GSE20347 | RCN1 | 5954 | 201063_at | 0.7197 | 0.0005 | |
| GSE23400 | RCN1 | 5954 | 201063_at | 0.9857 | 0.0000 | |
| GSE26886 | RCN1 | 5954 | 201063_at | 1.5665 | 0.0001 | |
| GSE29001 | RCN1 | 5954 | 201063_at | 1.1472 | 0.0005 | |
| GSE38129 | RCN1 | 5954 | 201063_at | 0.7330 | 0.0003 | |
| GSE45670 | RCN1 | 5954 | 201063_at | 0.4082 | 0.1041 | |
| GSE53622 | RCN1 | 5954 | 80415 | 1.0041 | 0.0000 | |
| GSE53624 | RCN1 | 5954 | 80415 | 1.0213 | 0.0000 | |
| GSE63941 | RCN1 | 5954 | 201063_at | -2.4257 | 0.0001 | |
| GSE77861 | RCN1 | 5954 | 201063_at | 0.8698 | 0.0260 | |
| GSE97050 | RCN1 | 5954 | A_23_P203299 | 0.2513 | 0.4277 | |
| SRP007169 | RCN1 | 5954 | RNAseq | 1.6482 | 0.0000 | |
| SRP008496 | RCN1 | 5954 | RNAseq | 1.7744 | 0.0000 | |
| SRP064894 | RCN1 | 5954 | RNAseq | 0.9912 | 0.0000 | |
| SRP133303 | RCN1 | 5954 | RNAseq | 1.3287 | 0.0000 | |
| SRP159526 | RCN1 | 5954 | RNAseq | 0.9073 | 0.0002 | |
| SRP193095 | RCN1 | 5954 | RNAseq | 0.8148 | 0.0000 | |
| SRP219564 | RCN1 | 5954 | RNAseq | 1.2067 | 0.0037 | |
| TCGA | RCN1 | 5954 | RNAseq | 0.2342 | 0.0002 |
Upregulated datasets: 8; Downregulated datasets: 1.
Survival by RCN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCN1 | 5954 | 1 | 8 | 21 | |
| GSE20123 | RCN1 | 5954 | 1 | 7 | 22 | |
| GSE43470 | RCN1 | 5954 | 3 | 4 | 36 | |
| GSE46452 | RCN1 | 5954 | 8 | 5 | 46 | |
| GSE47630 | RCN1 | 5954 | 3 | 10 | 27 | |
| GSE54993 | RCN1 | 5954 | 3 | 0 | 67 | |
| GSE54994 | RCN1 | 5954 | 4 | 10 | 39 | |
| GSE60625 | RCN1 | 5954 | 0 | 0 | 11 | |
| GSE74703 | RCN1 | 5954 | 3 | 2 | 31 | |
| GSE74704 | RCN1 | 5954 | 0 | 6 | 14 | |
| TCGA | RCN1 | 5954 | 12 | 24 | 60 |
Total number of gains: 38; Total number of losses: 76; Total Number of normals: 374.
Somatic mutations of RCN1:
Generating mutation plots.
Highly correlated genes for RCN1:
Showing top 20/1485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCN1 | WDR81 | 0.827795 | 4 | 0 | 4 |
| RCN1 | PREX1 | 0.818155 | 3 | 0 | 3 |
| RCN1 | RAB34 | 0.806352 | 3 | 0 | 3 |
| RCN1 | FADS1 | 0.798776 | 3 | 0 | 3 |
| RCN1 | SETD7 | 0.7985 | 3 | 0 | 3 |
| RCN1 | CCL5 | 0.788749 | 3 | 0 | 3 |
| RCN1 | PDIA5 | 0.786114 | 3 | 0 | 3 |
| RCN1 | FCGR3A | 0.778875 | 3 | 0 | 3 |
| RCN1 | NHS | 0.773907 | 3 | 0 | 3 |
| RCN1 | SLC35B2 | 0.773103 | 3 | 0 | 3 |
| RCN1 | ELP2 | 0.771969 | 3 | 0 | 3 |
| RCN1 | FOXF1 | 0.771199 | 3 | 0 | 3 |
| RCN1 | B4GALT4 | 0.764179 | 3 | 0 | 3 |
| RCN1 | RNF166 | 0.761607 | 3 | 0 | 3 |
| RCN1 | C11orf96 | 0.761475 | 3 | 0 | 3 |
| RCN1 | C18orf54 | 0.760225 | 4 | 0 | 4 |
| RCN1 | ZNF25 | 0.75646 | 3 | 0 | 3 |
| RCN1 | PYCR2 | 0.748784 | 3 | 0 | 3 |
| RCN1 | ZAP70 | 0.746577 | 3 | 0 | 3 |
| RCN1 | RICTOR | 0.743911 | 4 | 0 | 4 |
For details and further investigation, click here
