| Full name: coiled-coil domain containing 80 | Alias Symbol: URB|SSG1|DRO1|CL2 | ||
| Type: protein-coding gene | Cytoband: 3q13.2 | ||
| Entrez ID: 151887 | HGNC ID: HGNC:30649 | Ensembl Gene: ENSG00000091986 | OMIM ID: 608298 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC80 | 151887 | 225242_s_at | -0.9514 | 0.3522 | |
| GSE26886 | CCDC80 | 151887 | 225241_at | 0.3745 | 0.1935 | |
| GSE45670 | CCDC80 | 151887 | 225242_s_at | -3.1363 | 0.0000 | |
| GSE53622 | CCDC80 | 151887 | 139749 | -1.0922 | 0.0000 | |
| GSE53624 | CCDC80 | 151887 | 139749 | -0.4950 | 0.0089 | |
| GSE63941 | CCDC80 | 151887 | 225242_s_at | -5.1420 | 0.0073 | |
| GSE77861 | CCDC80 | 151887 | 225241_at | 0.0125 | 0.9319 | |
| GSE97050 | CCDC80 | 151887 | A_23_P58082 | -0.4543 | 0.2665 | |
| SRP007169 | CCDC80 | 151887 | RNAseq | 3.5183 | 0.0000 | |
| SRP008496 | CCDC80 | 151887 | RNAseq | 4.0953 | 0.0000 | |
| SRP064894 | CCDC80 | 151887 | RNAseq | 0.6713 | 0.1519 | |
| SRP133303 | CCDC80 | 151887 | RNAseq | -0.7852 | 0.0357 | |
| SRP159526 | CCDC80 | 151887 | RNAseq | -0.3570 | 0.5163 | |
| SRP193095 | CCDC80 | 151887 | RNAseq | 1.5278 | 0.0000 | |
| SRP219564 | CCDC80 | 151887 | RNAseq | 0.8329 | 0.4382 | |
| TCGA | CCDC80 | 151887 | RNAseq | -0.3559 | 0.0037 |
Upregulated datasets: 3; Downregulated datasets: 3.
Survival by CCDC80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC80 | 151887 | 17 | 1 | 12 | |
| GSE20123 | CCDC80 | 151887 | 17 | 1 | 12 | |
| GSE43470 | CCDC80 | 151887 | 20 | 1 | 22 | |
| GSE46452 | CCDC80 | 151887 | 13 | 5 | 41 | |
| GSE47630 | CCDC80 | 151887 | 16 | 6 | 18 | |
| GSE54993 | CCDC80 | 151887 | 2 | 5 | 63 | |
| GSE54994 | CCDC80 | 151887 | 29 | 4 | 20 | |
| GSE60625 | CCDC80 | 151887 | 0 | 6 | 5 | |
| GSE74703 | CCDC80 | 151887 | 16 | 1 | 19 | |
| GSE74704 | CCDC80 | 151887 | 13 | 1 | 6 | |
| TCGA | CCDC80 | 151887 | 52 | 7 | 37 |
Total number of gains: 195; Total number of losses: 38; Total Number of normals: 255.
Somatic mutations of CCDC80:
Generating mutation plots.
Highly correlated genes for CCDC80:
Showing top 20/1044 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC80 | LINC01279 | 0.821275 | 5 | 0 | 4 |
| CCDC80 | OLFML3 | 0.796913 | 7 | 0 | 7 |
| CCDC80 | RUNX1T1 | 0.796238 | 6 | 0 | 6 |
| CCDC80 | KANK2 | 0.790582 | 7 | 0 | 7 |
| CCDC80 | LRRN4CL | 0.789254 | 7 | 0 | 7 |
| CCDC80 | SVEP1 | 0.78887 | 6 | 0 | 6 |
| CCDC80 | MSRB3 | 0.788105 | 6 | 0 | 6 |
| CCDC80 | TNFSF12 | 0.784689 | 3 | 0 | 3 |
| CCDC80 | RNASE1 | 0.784388 | 6 | 0 | 6 |
| CCDC80 | OLFML1 | 0.781241 | 7 | 0 | 7 |
| CCDC80 | SATB1 | 0.779796 | 3 | 0 | 3 |
| CCDC80 | LAMA2 | 0.778632 | 5 | 0 | 5 |
| CCDC80 | DDR2 | 0.778385 | 8 | 0 | 7 |
| CCDC80 | DIXDC1 | 0.774947 | 6 | 0 | 6 |
| CCDC80 | ZEB2 | 0.773854 | 7 | 0 | 7 |
| CCDC80 | MRGPRF | 0.769805 | 7 | 0 | 7 |
| CCDC80 | ITGBL1 | 0.769152 | 4 | 0 | 4 |
| CCDC80 | CNRIP1 | 0.768638 | 8 | 0 | 7 |
| CCDC80 | RNASE4 | 0.768405 | 4 | 0 | 4 |
| CCDC80 | F13A1 | 0.767967 | 6 | 0 | 6 |
For details and further investigation, click here
