| Full name: ring finger protein 1 | Alias Symbol: RNF1 | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 6015 | HGNC ID: HGNC:10018 | Ensembl Gene: ENSG00000204227 | OMIM ID: 602045 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RING1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RING1 | 6015 | 35685_at | 0.3460 | 0.3924 | |
| GSE20347 | RING1 | 6015 | 35685_at | 0.1289 | 0.1584 | |
| GSE23400 | RING1 | 6015 | 35685_at | 0.1048 | 0.0011 | |
| GSE26886 | RING1 | 6015 | 35685_at | 0.4193 | 0.0018 | |
| GSE29001 | RING1 | 6015 | 35685_at | 0.1254 | 0.3642 | |
| GSE38129 | RING1 | 6015 | 35685_at | 0.0878 | 0.1697 | |
| GSE45670 | RING1 | 6015 | 35685_at | 0.0526 | 0.6646 | |
| GSE53622 | RING1 | 6015 | 80618 | 0.0570 | 0.3037 | |
| GSE53624 | RING1 | 6015 | 80618 | 0.1805 | 0.0049 | |
| GSE63941 | RING1 | 6015 | 35685_at | -0.0527 | 0.8694 | |
| GSE77861 | RING1 | 6015 | 35685_at | -0.0114 | 0.9518 | |
| GSE97050 | RING1 | 6015 | A_24_P200694 | 0.1167 | 0.6032 | |
| SRP007169 | RING1 | 6015 | RNAseq | 0.1203 | 0.7233 | |
| SRP008496 | RING1 | 6015 | RNAseq | 0.2599 | 0.2801 | |
| SRP064894 | RING1 | 6015 | RNAseq | 0.3589 | 0.0501 | |
| SRP133303 | RING1 | 6015 | RNAseq | 0.1648 | 0.3623 | |
| SRP159526 | RING1 | 6015 | RNAseq | 0.3613 | 0.2641 | |
| SRP193095 | RING1 | 6015 | RNAseq | 0.3103 | 0.0037 | |
| SRP219564 | RING1 | 6015 | RNAseq | 0.2020 | 0.4633 | |
| TCGA | RING1 | 6015 | RNAseq | 0.1159 | 0.0318 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RING1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RING1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RING1 | 6015 | 5 | 0 | 25 | |
| GSE20123 | RING1 | 6015 | 5 | 0 | 25 | |
| GSE43470 | RING1 | 6015 | 4 | 1 | 38 | |
| GSE46452 | RING1 | 6015 | 2 | 9 | 48 | |
| GSE47630 | RING1 | 6015 | 8 | 4 | 28 | |
| GSE54993 | RING1 | 6015 | 3 | 1 | 66 | |
| GSE54994 | RING1 | 6015 | 11 | 4 | 38 | |
| GSE60625 | RING1 | 6015 | 1 | 0 | 10 | |
| GSE74703 | RING1 | 6015 | 4 | 0 | 32 | |
| GSE74704 | RING1 | 6015 | 2 | 0 | 18 | |
| TCGA | RING1 | 6015 | 15 | 16 | 65 |
Total number of gains: 60; Total number of losses: 35; Total Number of normals: 393.
Somatic mutations of RING1:
Generating mutation plots.
Highly correlated genes for RING1:
Showing top 20/486 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RING1 | HNRNPUL1 | 0.821635 | 3 | 0 | 3 |
| RING1 | ABHD16A | 0.797226 | 3 | 0 | 3 |
| RING1 | PPP1R37 | 0.776723 | 3 | 0 | 3 |
| RING1 | CCAR1 | 0.752115 | 3 | 0 | 3 |
| RING1 | NOP58 | 0.738487 | 3 | 0 | 3 |
| RING1 | SSBP4 | 0.737528 | 3 | 0 | 3 |
| RING1 | RNF2 | 0.729574 | 3 | 0 | 3 |
| RING1 | RCN1 | 0.729462 | 3 | 0 | 3 |
| RING1 | MDGA1 | 0.729314 | 3 | 0 | 3 |
| RING1 | PRR12 | 0.725871 | 3 | 0 | 3 |
| RING1 | POGLUT1 | 0.725075 | 3 | 0 | 3 |
| RING1 | ZNF628 | 0.724778 | 4 | 0 | 4 |
| RING1 | ZNF579 | 0.72359 | 3 | 0 | 3 |
| RING1 | USE1 | 0.721768 | 3 | 0 | 3 |
| RING1 | NMT1 | 0.705766 | 3 | 0 | 3 |
| RING1 | RAB15 | 0.705544 | 3 | 0 | 3 |
| RING1 | ZNF668 | 0.702355 | 4 | 0 | 4 |
| RING1 | MADD | 0.701911 | 4 | 0 | 4 |
| RING1 | DMAP1 | 0.699324 | 5 | 0 | 5 |
| RING1 | TAP1 | 0.696794 | 3 | 0 | 3 |
For details and further investigation, click here
