| Full name: mediator complex subunit 11 | Alias Symbol: HSPC296|MGC88387 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 400569 | HGNC ID: HGNC:32687 | Ensembl Gene: ENSG00000161920 | OMIM ID: 612383 |
| Drug and gene relationship at DGIdb | |||
Expression of MED11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED11 | 400569 | 226958_s_at | -0.3363 | 0.1219 | |
| GSE26886 | MED11 | 400569 | 226958_s_at | 0.6872 | 0.0020 | |
| GSE45670 | MED11 | 400569 | 226958_s_at | -0.2278 | 0.0299 | |
| GSE53622 | MED11 | 400569 | 11469 | -0.2032 | 0.0004 | |
| GSE53624 | MED11 | 400569 | 11469 | -0.3375 | 0.0001 | |
| GSE63941 | MED11 | 400569 | 226958_s_at | 0.0985 | 0.8545 | |
| GSE77861 | MED11 | 400569 | 226958_s_at | -0.2686 | 0.1301 | |
| GSE97050 | MED11 | 400569 | A_23_P425587 | 0.0539 | 0.8190 | |
| SRP007169 | MED11 | 400569 | RNAseq | -0.6723 | 0.1168 | |
| SRP008496 | MED11 | 400569 | RNAseq | -0.5967 | 0.0519 | |
| SRP064894 | MED11 | 400569 | RNAseq | 0.1046 | 0.6432 | |
| SRP133303 | MED11 | 400569 | RNAseq | -0.4079 | 0.0476 | |
| SRP159526 | MED11 | 400569 | RNAseq | -0.6468 | 0.0004 | |
| SRP193095 | MED11 | 400569 | RNAseq | -0.5233 | 0.0000 | |
| SRP219564 | MED11 | 400569 | RNAseq | -0.0620 | 0.8436 | |
| TCGA | MED11 | 400569 | RNAseq | -0.1032 | 0.1759 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED11 | 400569 | 5 | 2 | 23 | |
| GSE20123 | MED11 | 400569 | 5 | 3 | 22 | |
| GSE43470 | MED11 | 400569 | 1 | 6 | 36 | |
| GSE46452 | MED11 | 400569 | 34 | 1 | 24 | |
| GSE47630 | MED11 | 400569 | 7 | 1 | 32 | |
| GSE54993 | MED11 | 400569 | 4 | 3 | 63 | |
| GSE54994 | MED11 | 400569 | 5 | 9 | 39 | |
| GSE60625 | MED11 | 400569 | 4 | 0 | 7 | |
| GSE74703 | MED11 | 400569 | 1 | 3 | 32 | |
| GSE74704 | MED11 | 400569 | 3 | 1 | 16 | |
| TCGA | MED11 | 400569 | 19 | 21 | 56 |
Total number of gains: 88; Total number of losses: 50; Total Number of normals: 350.
Somatic mutations of MED11:
Generating mutation plots.
Highly correlated genes for MED11:
Showing top 20/50 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED11 | SAMD13 | 0.719027 | 3 | 0 | 3 |
| MED11 | NINJ2 | 0.717102 | 3 | 0 | 3 |
| MED11 | UBXN6 | 0.703791 | 3 | 0 | 3 |
| MED11 | ZNF226 | 0.682947 | 4 | 0 | 3 |
| MED11 | ARFIP2 | 0.669606 | 3 | 0 | 3 |
| MED11 | ABCB1 | 0.665547 | 4 | 0 | 3 |
| MED11 | ACADS | 0.639657 | 4 | 0 | 3 |
| MED11 | APOM | 0.630433 | 4 | 0 | 3 |
| MED11 | GALK1 | 0.629649 | 5 | 0 | 4 |
| MED11 | PTGDS | 0.626449 | 5 | 0 | 3 |
| MED11 | ACSM5 | 0.620711 | 4 | 0 | 3 |
| MED11 | LENG1 | 0.62048 | 4 | 0 | 3 |
| MED11 | FBXL15 | 0.61653 | 4 | 0 | 3 |
| MED11 | CNTN4 | 0.610517 | 4 | 0 | 3 |
| MED11 | FAM184A | 0.609159 | 3 | 0 | 3 |
| MED11 | AP4B1 | 0.607648 | 5 | 0 | 4 |
| MED11 | TMEM243 | 0.604579 | 3 | 0 | 3 |
| MED11 | SWI5 | 0.591314 | 3 | 0 | 3 |
| MED11 | FOXO4 | 0.589032 | 4 | 0 | 3 |
| MED11 | P2RY14 | 0.58876 | 4 | 0 | 3 |
For details and further investigation, click here
