| Full name: galactokinase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 2584 | HGNC ID: HGNC:4118 | Ensembl Gene: ENSG00000108479 | OMIM ID: 604313 |
| Drug and gene relationship at DGIdb | |||
Expression of GALK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALK1 | 2584 | 204374_s_at | -0.3471 | 0.3813 | |
| GSE20347 | GALK1 | 2584 | 204374_s_at | -0.4365 | 0.0000 | |
| GSE23400 | GALK1 | 2584 | 204374_s_at | -0.2449 | 0.0000 | |
| GSE26886 | GALK1 | 2584 | 229458_s_at | 0.0511 | 0.7797 | |
| GSE29001 | GALK1 | 2584 | 204374_s_at | -0.1645 | 0.1269 | |
| GSE38129 | GALK1 | 2584 | 204374_s_at | -0.2794 | 0.0061 | |
| GSE45670 | GALK1 | 2584 | 204374_s_at | -0.0081 | 0.9692 | |
| GSE53622 | GALK1 | 2584 | 106944 | -0.2459 | 0.0214 | |
| GSE53624 | GALK1 | 2584 | 106944 | -0.2688 | 0.0050 | |
| GSE63941 | GALK1 | 2584 | 204374_s_at | 0.7040 | 0.0347 | |
| GSE77861 | GALK1 | 2584 | 229458_s_at | -0.2805 | 0.0065 | |
| GSE97050 | GALK1 | 2584 | A_33_P3375910 | -0.0555 | 0.7743 | |
| SRP007169 | GALK1 | 2584 | RNAseq | -1.6935 | 0.0000 | |
| SRP008496 | GALK1 | 2584 | RNAseq | -1.5235 | 0.0000 | |
| SRP064894 | GALK1 | 2584 | RNAseq | 0.5704 | 0.0626 | |
| SRP133303 | GALK1 | 2584 | RNAseq | -0.3529 | 0.0318 | |
| SRP159526 | GALK1 | 2584 | RNAseq | -0.2827 | 0.0852 | |
| SRP193095 | GALK1 | 2584 | RNAseq | -0.6612 | 0.0000 | |
| SRP219564 | GALK1 | 2584 | RNAseq | -0.5820 | 0.0869 | |
| TCGA | GALK1 | 2584 | RNAseq | 0.1473 | 0.0565 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GALK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALK1 | 2584 | 7 | 2 | 21 | |
| GSE20123 | GALK1 | 2584 | 7 | 2 | 21 | |
| GSE43470 | GALK1 | 2584 | 5 | 3 | 35 | |
| GSE46452 | GALK1 | 2584 | 34 | 0 | 25 | |
| GSE47630 | GALK1 | 2584 | 8 | 1 | 31 | |
| GSE54993 | GALK1 | 2584 | 2 | 5 | 63 | |
| GSE54994 | GALK1 | 2584 | 10 | 4 | 39 | |
| GSE60625 | GALK1 | 2584 | 6 | 0 | 5 | |
| GSE74703 | GALK1 | 2584 | 5 | 1 | 30 | |
| GSE74704 | GALK1 | 2584 | 5 | 1 | 14 | |
| TCGA | GALK1 | 2584 | 32 | 9 | 55 |
Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.
Somatic mutations of GALK1:
Generating mutation plots.
Highly correlated genes for GALK1:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALK1 | C3orf35 | 0.78597 | 3 | 0 | 3 |
| GALK1 | UBXN6 | 0.735801 | 3 | 0 | 3 |
| GALK1 | CTSE | 0.733908 | 3 | 0 | 3 |
| GALK1 | ADAMTS17 | 0.720723 | 3 | 0 | 3 |
| GALK1 | BCL2L15 | 0.718947 | 4 | 0 | 3 |
| GALK1 | FXYD2 | 0.717959 | 3 | 0 | 3 |
| GALK1 | AP4B1 | 0.698642 | 4 | 0 | 4 |
| GALK1 | FGF17 | 0.698335 | 3 | 0 | 3 |
| GALK1 | NLRP6 | 0.697038 | 4 | 0 | 3 |
| GALK1 | FAM3D | 0.695415 | 3 | 0 | 3 |
| GALK1 | ASPDH | 0.685448 | 3 | 0 | 3 |
| GALK1 | GALNT5 | 0.684678 | 3 | 0 | 3 |
| GALK1 | CYP4Z1 | 0.678175 | 3 | 0 | 3 |
| GALK1 | CD200R1 | 0.677007 | 3 | 0 | 3 |
| GALK1 | DLK2 | 0.672146 | 4 | 0 | 3 |
| GALK1 | ST3GAL3 | 0.667325 | 3 | 0 | 3 |
| GALK1 | ODF4 | 0.662691 | 4 | 0 | 3 |
| GALK1 | CYB5D2 | 0.658427 | 3 | 0 | 3 |
| GALK1 | SPNS3 | 0.652628 | 5 | 0 | 4 |
| GALK1 | TMEM101 | 0.652196 | 5 | 0 | 5 |
For details and further investigation, click here
