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Multi-Omics Database of ESCC

 

ARFIP2

 

Full name: ADP ribosylation factor interacting protein 2 Alias Symbol: POR1
Type: protein-coding gene Cytoband: 11p15.4
Entrez ID: 23647 HGNC ID: HGNC:17160 Ensembl Gene: ENSG00000132254 OMIM ID: 601638
Drug and gene relationship at DGIdb

 

Expression of ARFIP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ARFIP2 23647 202109_at -0.0929 0.8162
GSE20347 ARFIP2 23647 202109_at -0.3045 0.0325
GSE23400 ARFIP2 23647 202109_at -0.0248 0.6577
GSE26886 ARFIP2 23647 202109_at 0.5550 0.0001
GSE29001 ARFIP2 23647 202109_at -0.2788 0.2079
GSE38129 ARFIP2 23647 202109_at -0.1738 0.1442
GSE45670 ARFIP2 23647 202109_at 0.0200 0.8991
GSE53622 ARFIP2 23647 45509 -0.1428 0.0424
GSE53624 ARFIP2 23647 45509 -0.2640 0.0001
GSE63941 ARFIP2 23647 202109_at 0.6426 0.0636
GSE77861 ARFIP2 23647 202109_at -0.0046 0.9883
GSE97050 ARFIP2 23647 A_23_P139228 0.1989 0.3580
SRP007169 ARFIP2 23647 RNAseq -0.7713 0.0509
SRP008496 ARFIP2 23647 RNAseq -0.4876 0.0567
SRP064894 ARFIP2 23647 RNAseq -0.4075 0.0325
SRP133303 ARFIP2 23647 RNAseq -0.2321 0.1063
SRP159526 ARFIP2 23647 RNAseq -0.4883 0.0363
SRP193095 ARFIP2 23647 RNAseq -0.3696 0.0000
SRP219564 ARFIP2 23647 RNAseq 0.0015 0.9964
TCGA ARFIP2 23647 RNAseq -0.2315 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ARFIP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ARFIP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ARFIP2 23647 1 11 18
GSE20123 ARFIP2 23647 1 11 18
GSE43470 ARFIP2 23647 1 8 34
GSE46452 ARFIP2 23647 7 8 44
GSE47630 ARFIP2 23647 2 12 26
GSE54993 ARFIP2 23647 3 1 66
GSE54994 ARFIP2 23647 2 12 39
GSE60625 ARFIP2 23647 0 0 11
GSE74703 ARFIP2 23647 1 6 29
GSE74704 ARFIP2 23647 0 8 12
TCGA ARFIP2 23647 8 39 49

Total number of gains: 26; Total number of losses: 116; Total Number of normals: 346.  

 

Somatic mutations of ARFIP2:

 

Generating mutation plots.

 

Highly correlated genes for ARFIP2:

 

Showing top 20/81 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ARFIP2MGAT5B0.795857303
ARFIP2FFAR10.770273303
ARFIP2VCX20.721827303
ARFIP2DRD40.704448303
ARFIP2CABP10.684832404
ARFIP2SCN2B0.683985303
ARFIP2MOGAT30.678246303
ARFIP2ATXN7L20.673219404
ARFIP2MED110.669606303
ARFIP2RIN10.665123403
ARFIP2MICALL10.657238303
ARFIP2ASGR20.652924303
ARFIP2HMGCLL10.649252303
ARFIP2FASTK0.645382404
ARFIP2KAT80.643544504
ARFIP2PEX11G0.63516503
ARFIP2SIRT60.632647503
ARFIP2TRIM410.627788403
ARFIP2OR12D20.626828303
ARFIP2NUDT220.624474604

For details and further investigation, click here